Ajwain dry extract 91745-13-0 MANUFACTURER EXPORTER MEDIOCON INC

 

Ajwain dry extract  Manufactured by Mediocon INC

 

·   Name: Ajwain dry extract 

 

·    CAS No :   91745-13-0

 

·   MolecularWeight: NA

 

Molecular    formula : NA​

·    Synonyms :   ( ( Trachyspermum ammi L. Sprague )   

 

·    Appearance:   a light brownish-green to a darker brownish-green color powder.

 

·   Solubility:   1. Ajwain dry extract  Manufactured by Mediocon INCis slightly soluble in water,  more soluble in ethanol.

 

 

·   Use:

 

Pharmaceutical Applications:

1. Digestive issues: Ajwain dry extract  Manufactured by Mediocon INCis used to treat digestive issues, such as indigestion, bloating, and gas.

2. Respiratory problems: Ajwain dry extract  Manufactured by Mediocon INCis used to treat respiratory problems, such as bronchitis, asthma, and coughs.

3. Pain relief: Ajwain dry extract  Manufactured by Mediocon INCis used as a natural pain reliever for headaches, muscle aches, and joint pain.

4. Antimicrobial properties: Ajwain dry extract  Manufactured by Mediocon INCis used to treat microbial infections, such as bacterial, viral, and fungal infections.

 

Food and Beverage Applications:

1. Spice blends: Ajwain dry extract  Manufactured by Mediocon INCis used in spice blends to add flavor and aroma to various dishes.

2. Beverages: Ajwain dry extract  Manufactured by Mediocon INCis used in beverages, such as teas, coffees, and juices, to add flavor and health benefits.

3. Baked goods: Ajwain dry extract  Manufactured by Mediocon INCis used in baked goods, such as bread, cakes, and cookies, to add flavor and aroma.

 

Cosmetic Applications:

1. Skin care: Ajwain dry extract  Manufactured by Mediocon INCis used in skin care products to treat acne, reduce inflammation, and improve skin texture.

2. Hair care: Ajwain dry extract  Manufactured by Mediocon INCis used in hair care products to treat dandruff, reduce hair loss, and improve hair texture.

3. Oral care: Ajwain dry extract  Manufactured by Mediocon INCis used in oral care products to treat gum inflammation, reduce plaque, and freshen breath.

 

Other Applications:

1. Agriculture: Ajwain dry extract  Manufactured by Mediocon INCis used in agriculture as a natural pesticide and fungicide.

2. Veterinary medicine: Ajwain dry extract  Manufactured by Mediocon INCis used in veterinary medicine to treat digestive issues, respiratory problems, and skin infections in animals.

3. Insect repellent: Ajwain dry extract  Manufactured by Mediocon INCis used as a natural insect repellent to repel mosquitoes, flies, and other insects.

 

·      How is Ajwain dry extract  Manufactured by Mediocon INCsynthesized?

Step 1: Harvesting and Cleaning:

1. Harvesting: Fresh ajwain seeds or leaves are harvested from the Trachyspermum ammi plant.

2. Cleaning: The harvested seeds or leaves are cleaned to remove any dirt, debris, or impurities.

 

Step 2: Drying:

1. Drying: The cleaned seeds or leaves are dried to remove excess moisture.

2. Drying methods: Various drying methods can be used, such as air drying, oven drying, or freeze-drying.

 

Step 3: Extraction:

1. Solvent selection: A suitable solvent, such as ethanol, methanol, or water, is selected for extraction.

2. Extraction methods: Various extraction methods can be used, such as maceration, percolation, or Soxhlet extraction.

3. Extraction conditions: The extraction conditions, such as temperature, pressure, and time, are optimized to maximize the yield of bioactive compounds.

 

Step 4: Filtration and Concentration:

1. Filtration: The extracted solution is filtered to remove any impurities or sediment.

2. Concentration: The filtered solution is concentrated using various methods, such as evaporation, distillation, or freeze-drying.

 

Step 5: Drying and Powderization:

1. Drying: The concentrated solution is dried to produce a dry extract.

2. Powderization: The dry extract is powderized to produce a uniform powder.

 

Step 6: Quality Control and Packaging:

1. Quality control: The final product is tested for quality, purity, and potency.

2. Packaging: The Ajwain dry extract  Manufactured by Mediocon INCis packaged in airtight containers to maintain its quality and shelf-life.

Manufacturing Process Variations:

1. Variations in extraction methods: Different extraction methods, such as ultrasonic-assisted extraction or microwave-assisted extraction, can be used to optimize the extraction process.

2. Variations in solvent selection: Different solvents, such as glycerin or propylene glycol, can be used to optimize the extraction process.

3. Variations in drying methods: Different drying methods, such as spray drying or freeze-drying, can be used to optimize the drying process..

 

·         How Ajwain dry extract  Manufactured by Mediocon INCDosage Forms are prepared?

 

Tablet Dosage Form:

1. Weighing and mixing: Ajwain dry extract  Manufactured by Mediocon INCis weighed and mixed with other ingredients, such as binders, fillers, and lubricants.

2. Granulation: The mixture is granulated to form a uniform powder.

3. Tablet compression: The granules are compressed into tablets using a tablet press.

 

Capsule Dosage Form:

1. Weighing and mixing: Ajwain dry extract  Manufactured by Mediocon INCis weighed and mixed with other ingredients, such as fillers and lubricants.

2. Filling: The mixture is filled into empty capsules.

3. Sealing: The capsules are sealed using a capsule sealing machine.

 

Powder Dosage Form:

1. Weighing and mixing: Ajwain dry extract  Manufactured by Mediocon INCis weighed and mixed with other ingredients, such as fillers and lubricants.

2. Sifting: The mixture is sifted to form a uniform powder.

3. Packaging: The powder is packaged in airtight containers.

 

Liquid Dosage Form:

1. Weighing and mixing: Ajwain dry extract  Manufactured by Mediocon INCis weighed and mixed with a solvent, such as water or ethanol.

2. Dissolution: The mixture is stirred until the Ajwain dry extract  Manufactured by Mediocon INCis fully dissolved.

3. Filtration: The solution is filtered to remove any impurities.

4. Packaging: The solution is packaged in airtight containers.

 

Semi-Solid Dosage Form:

1. Weighing and mixing: Ajwain dry extract  Manufactured by Mediocon INCis weighed and mixed with a base, such as petroleum jelly or beeswax.

2. Melting: The mixture is melted until the base is fully dissolved.

3. Cooling: The mixture is cooled until it solidifies.

4. Packaging: The semi-solid mixture is packaged in airtight containers.

 

Quality Control:

1. Weight variation: The weight of each dosage unit is checked to ensure it is within the acceptable range.

2. Content uniformity: The content of each dosage unit is checked to ensure it is within the acceptable range.

3. Dissolution: The dissolution rate of each dosage unit is checked to ensure it meets the required standards.

4. Microbial contamination: The dosage units are checked for microbial contamination to ensure they meet the required standards.

 

·         What are the appropriate Dosage forms of Ajwain dry extract?

Oral Dosage Forms:

1. Tablets: Ajwain dry extract  Manufactured by Mediocon INCcan be formulated into tablets for oral administration.

2. Capsules: Ajwain dry extract  Manufactured by Mediocon INCcan be filled into capsules for oral administration.

3. Powder: Ajwain dry extract  Manufactured by Mediocon INCcan be packaged as a powder for oral administration, often mixed with water or other liquids.

4. Liquid extract: Ajwain dry extract  Manufactured by Mediocon INCcan be dissolved in a solvent, such as water or ethanol, to create a liquid extract.

 

Topical Dosage Forms:

1. Creams: Ajwain dry extract  Manufactured by Mediocon INCcan be formulated into creams for topical application.

2. Ointments: Ajwain dry extract  Manufactured by Mediocon INCcan be formulated into ointments for topical application.

3. Gels: Ajwain dry extract  Manufactured by Mediocon INCcan be formulated into gels for topical application.

4. Pastes: Ajwain dry extract  Manufactured by Mediocon INCcan be formulated into pastes for topical application.

 

Parenteral Dosage Forms:

1. Injectable solutions: Ajwain dry extract  Manufactured by Mediocon INCcan be formulated into injectable solutions for parenteral administration.

2. Injectable suspensions: Ajwain dry extract  Manufactured by Mediocon INCcan be formulated into injectable suspensions for parenteral administration.

 

Other Dosage Forms:

1. Suppositories: Ajwain dry extract  Manufactured by Mediocon INCcan be formulated into suppositories for rectal administration.

2. Pessaries: Ajwain dry extract  Manufactured by Mediocon INCcan be formulated into pessaries for vaginal administration.

Considerations:

1. Bioavailability: The dosage form should ensure optimal bioavailability of the active compounds.

2. Stability: The dosage form should ensure stability of the active compounds during storage and administration.

3. Patient compliance: The dosage form should be convenient and easy to administer to ensure patient compliance.

4. Regulatory requirements: The dosage form should comply with regulatory requirements, such as Good Manufacturing Practice (GMP) guidelines.

 

·         When should Ajwain dry extract  Manufactured by Mediocon INCbe taken?

For Digestive Issues:

1. Before meals: Take Ajwain dry extract  Manufactured by Mediocon INC30 minutes to 1 hour before meals to help stimulate digestion and relieve symptoms of indigestion and bloating.

2. After meals: Take Ajwain dry extract  Manufactured by Mediocon INC1-2 hours after meals to help alleviate symptoms of indigestion, bloating, and gas.

 

For Respiratory Issues:

1. Morning and evening: Take Ajwain dry extract  Manufactured by Mediocon INCin the morning and evening to help relieve symptoms of bronchitis, asthma, and coughs.

2. As needed: Take Ajwain dry extract  Manufactured by Mediocon INCas needed to help relieve acute respiratory symptoms, such as coughing or wheezing.

 

For General Health and Wellness:

1. Morning: Take Ajwain dry extract  Manufactured by Mediocon INCin the morning to help boost energy and vitality.

2. Before bedtime: Take Ajwain dry extract  Manufactured by Mediocon INCbefore bedtime to help promote relaxation and improve sleep quality.

 

Special Considerations:

1. Pregnancy and breastfeeding: Consult with a healthcare professional before taking Ajwain dry extract  Manufactured by Mediocon INCduring pregnancy or breastfeeding.

2. Children: Consult with a healthcare professional before giving Ajwain dry extract  Manufactured by Mediocon INCto children.

3. Surgery: Stop taking Ajwain dry extract  Manufactured by Mediocon INCat least 2 weeks before surgery to avoid any potential interactions with anesthetics or other medications.

 

Dosage:

1. Start with a low dose: Begin with a low dose (250-500 mg) and gradually increase as needed and under the guidance of a healthcare professional.

2. Follow the recommended dosage: Follow the recommended dosage on the label or as instructed by a healthcare professional.

 

·      What are the effects And Side effects of Ajwain Dry extract?

Positive Effects:

1. Digestive aid: Ajwain dry extract  Manufactured by Mediocon INCmay help alleviate digestive issues, such as bloating, gas, and indigestion.

2. Antimicrobial properties: Ajwain dry extract  Manufactured by Mediocon INChas antimicrobial properties, which may help prevent infections and promote wound healing.

3. Anti-inflammatory effects: Ajwain dry extract  Manufactured by Mediocon INCmay help reduce inflammation and alleviate symptoms associated with conditions like arthritis.

4. Antioxidant properties: Ajwain dry extract  Manufactured by Mediocon INChas antioxidant properties, which may help protect against cell damage and oxidative stress.

 

Negative Effects:

1. Gastrointestinal upset: Consuming large amounts of Ajwain dry extract  Manufactured by Mediocon INCcan cause gastrointestinal upset, including nausea, vomiting, and diarrhea.

2. Allergic reactions: Some individuals may be allergic to Ajwain and experience symptoms like hives, itching, and swelling.

3. Interaction with medications: Ajwain dry extract  Manufactured by Mediocon INCmay interact with certain medications, such as blood thinners, diabetes medications, and blood pressure medications.

4. Pregnancy and breastfeeding: Ajwain dry extract  Manufactured by Mediocon INCmay stimulate uterine contractions and affect milk production, so it's recommended to consult a healthcare professional before using it during pregnancy or breastfeeding.

 

Side Effects:

1. Digestive issues: Ajwain dry extract  Manufactured by Mediocon INCcan cause digestive issues, such as bloating, gas, and stomach cramps, especially when consumed in excess.

2. Skin irritation: Ajwain dry extract  Manufactured by Mediocon INCcan cause skin irritation, such as redness, itching, and rashes, especially when applied topically.

3. Respiratory issues: Ajwain dry extract  Manufactured by Mediocon INCcan cause respiratory issues, such as coughing, wheezing, and shortness of breath, especially in individuals with pre-existing respiratory conditions.

4. Cardiovascular effects: Ajwain dry extract  Manufactured by Mediocon INCmay lower blood pressure and heart rate, which can be beneficial for some individuals but may also cause issues for those with pre-existing cardiovascular conditions.

 

Contraindications:

1. Pregnancy and breastfeeding: Ajwain dry extract  Manufactured by Mediocon INCmay stimulate uterine contractions and affect milk production, so it's recommended to consult a healthcare professional before using it during pregnancy or breastfeeding.

2. Surgery: Ajwain dry extract  Manufactured by Mediocon INCmay increase the risk of bleeding during surgery, so it's recommended to stop using it at least 2 weeks before surgery.

3. Kidney or liver disease: Individuals with kidney or liver disease should consult with a healthcare professional before using Ajwain dry extract, as it may exacerbate these conditions.

 

Precautions:

1. Start with a low dose: Begin with a low dose (250-500 mg) and gradually increase as needed and under the guidance of a healthcare professional.

2. Monitor blood sugar levels: Individuals with diabetes should monitor their blood sugar levels closely while using Ajwain dry extract, as it may affect blood sugar control.

3. Consult with a healthcare professional: Consult with a healthcare professional before using Ajwain dry extract, especially if you have any underlying health conditions or are taking medications.

 

·      How is Ajwain dry extract  Manufactured by Mediocon INCtested qualitatively?

Organoleptic Tests:

1. Visual inspection: Check the color, texture, and appearance of the extract.

2. Odor: Check the characteristic odor of the extract.

3. Taste: Check the characteristic taste of the extract.

 

Chemical Tests:

1. Solubility test: Check the solubility of the extract in different solvents, such as water, ethanol, or chloroform.

2. pH test: Check the pH of the extract using pH paper or a pH meter.

3. Alkaloid test: Check for the presence of alkaloids using tests such as the Dragendorff's test or the Mayer's test.

 

Chromatographic Tests:

1. Thin Layer Chromatography (TLC): Separate and identify the components of the extract using TLC.

2. High-Performance Liquid Chromatography (HPLC): Separate and quantify the components of the extract using HPLC.

 

Spectroscopic Tests:

1. Infrared (IR) spectroscopy: Identify the functional groups present in the extract using IR spectroscopy.

2. Nuclear Magnetic Resonance (NMR) spectroscopy: Identify the structure of the components present in the extract using NMR spectroscopy.

 

Microbiological Tests:

1. Total bacterial count: Check the total bacterial count of the extract using microbiological tests.

2. Total fungal count: Check the total fungal count of the extract using microbiological tests.

 

Other Tests:

1. Moisture content: Check the moisture content of the extract using methods such as the Karl Fischer titration.

2. Ash content: Check the ash content of the extract using methods such as the ignition method.

 

·         Which tests are performed on Ajwain dry extract?

Physical Tests:

1. Appearance: Visual inspection to check the color, texture, and appearance.

2. Odor: Organoleptic evaluation to check the characteristic odor.

3. Taste: Organoleptic evaluation to check the characteristic taste.

4. Moisture content: Karl Fischer titration or loss on drying to check the moisture content.

5. Ash content: Ignition method to check the ash content.

Chemical Tests:

1. pH: pH meter or pH paper to check the pH.

2. Solubility: Solubility test to check the solubility in different solvents.

3. Alkaloid content: Tests such as Dragendorff's test or Mayer's test to check the alkaloid content.

4. Thymol content: High-Performance Liquid Chromatography (HPLC) or Gas Chromatography (GC) to check the thymol content.

 

Chromatographic Tests:

1. Thin Layer Chromatography (TLC): TLC to separate and identify the components.

2. High-Performance Liquid Chromatography (HPLC): HPLC to separate and quantify the components.

3. Gas Chromatography (GC): GC to separate and quantify the components.

 

Spectroscopic Tests:

1. Infrared (IR) spectroscopy: IR spectroscopy to identify the functional groups.

2. Nuclear Magnetic Resonance (NMR) spectroscopy: NMR spectroscopy to identify the structure of the components.

Microbiological Tests:

1. Total bacterial count: Microbiological tests to check the total bacterial count.

2. Total fungal count: Microbiological tests to check the total fungal count.

3. Pathogen testing: Microbiological tests to check for pathogens such as E. coli, Salmonella, and Staphylococcus aureus.

Heavy Metal Tests:

1. Lead: Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) to check the lead content.

2. Mercury: AAS or ICP-MS to check the mercury content.

3. Arsenic: AAS or ICP-MS to check the arsenic content.

4. Cadmium: AAS or ICP-MS to check the cadmium content.

Pesticide Residue Tests:

1. Gas Chromatography-Mass Spectrometry (GC-MS): GC-MS to check for pesticide residues.

2. Liquid Chromatography-Mass Spectrometry (LC-MS): LC-MS to check for pesticide residues.

 

·         What are the challenges in Manufacturing of Ajwain dry extract?

 

Raw Material Challenges:

1. Quality and consistency: Ensuring consistent quality and supply of raw materials, such as Ajwain seeds or leaves.

2. Contamination: Risk of contamination with heavy metals, pesticides, or other impurities.

3. Seasonal availability: Ajwain seeds or leaves may be available only during certain seasons, affecting production.

 

Extraction Challenges:

1. Optimizing extraction conditions: Finding the optimal extraction conditions, such as solvent, temperature, and time, to maximize yield and quality.

2. Scalability: Scaling up extraction processes while maintaining quality and consistency.

3. Solvent selection: Choosing the right solvent that is safe, efficient, and environmentally friendly.

 

Drying Challenges:

1. Moisture control: Controlling moisture levels during drying to prevent degradation or contamination.

2. Temperature control: Maintaining optimal drying temperatures to preserve bioactive compounds.

3. Equipment selection: Choosing the right drying equipment that can handle the specific requirements of Ajwain dry extract.

 

Quality Control Challenges:

1. Standardization: Standardizing the extract to ensure consistent quality and bioactive compound content.

2. Testing and validation: Conducting thorough testing and validation to ensure compliance with regulatory requirements.

3. Stability testing: Conducting stability testing to ensure the extract remains stable and effective over time.

 

Regulatory Challenges:

1. Compliance with regulations: Ensuring compliance with local and international regulations, such as Good Manufacturing Practice (GMP) guidelines.

2. Labeling and claims: Ensuring accurate labeling and claims that comply with regulatory requirements.

3. Import and export regulations: Navigating import and export regulations for raw materials and finished products.

 

Equipment and Maintenance Challenges:

1. Equipment selection and maintenance: Choosing the right equipment and maintaining it properly to ensure efficient and safe production.

2. Cleaning and sanitation: Ensuring proper cleaning and sanitation of equipment to prevent contamination.

3. Energy efficiency: Optimizing energy efficiency to reduce costs and environmental impact.

 

Supply Chain Challenges:

1. Raw material sourcing: Ensuring a reliable and sustainable supply of raw materials.

2. Transportation and storage: Ensuring proper transportation and storage of raw materials and finished products.

3. Inventory management: Managing inventory levels to ensure timely delivery and minimize waste.

 

·         What are the challenges in manufacturing of Ajwain dry extract  Manufactured by Mediocon INCDosage forms?

Tablet Dosage Form Challenges:

1. Flowability and compressibility: Ensuring the Ajwain dry extract  Manufactured by Mediocon INCpowder flows well and can be compressed into tablets.

2. Binding and disintegration: Ensuring the tablets have sufficient binding properties to hold together, yet disintegrate properly in the body.

3. Content uniformity: Ensuring the Ajwain dry extract  Manufactured by Mediocon INCis evenly distributed throughout the tablet.

4. Hardness and friability: Ensuring the tablets have the right hardness and friability to withstand handling and storage.

 

Capsule Dosage Form Challenges:

1. Fill weight and volume: Ensuring the correct fill weight and volume of Ajwain dry extract  Manufactured by Mediocon INCin each capsule.

2. Moisture content: Ensuring the moisture content of the Ajwain dry extract  Manufactured by Mediocon INCis within acceptable limits to prevent degradation.

3. Capsule shell integrity: Ensuring the capsule shell remains intact and does not leak or burst during storage or handling.

4. Content uniformity: Ensuring the Ajwain dry extract  Manufactured by Mediocon INCis evenly distributed throughout the capsule.

 

Powder Dosage Form Challenges:

1. Flowability and dusting: Ensuring the Ajwain dry extract  Manufactured by Mediocon INCpowder flows well and does not create excessive dust.

2. Sifting and segregation: Ensuring the powder is sifted and segregated properly to prevent clogging and uneven distribution.

3. Moisture content: Ensuring the moisture content of the Ajwain dry extract  Manufactured by Mediocon INCis within acceptable limits to prevent degradation.

4. Packaging and storage: Ensuring the powder is packaged and stored properly to prevent contamination and degradation.

 

Liquid Dosage Form Challenges:

1. Solubility and stability: Ensuring the Ajwain dry extract  Manufactured by Mediocon INCis soluble and stable in the liquid dosage form.

2. Preservation and antimicrobial activity: Ensuring the liquid dosage form has sufficient preservation and antimicrobial activity to prevent contamination.

3. pH and buffering: Ensuring the pH and buffering capacity of the liquid dosage form are within acceptable limits.

4. Packaging and storage: Ensuring the liquid dosage form is packaged and stored properly to prevent contamination and degradation.

 

Semi-Solid Dosage Form Challenges:

1. Rheology and texture: Ensuring the semi-solid dosage form has the right rheology and texture for application and absorption.

2. Stability and degradation: Ensuring the semi-solid dosage form is stable and does not degrade over time.

3. Preservation and antimicrobial activity: Ensuring the semi-solid dosage form has sufficient preservation and antimicrobial activity to prevent contamination.

4. Packaging and storage: Ensuring the semi-solid dosage form is packaged and stored properly to prevent contamination and degradation.

 

 

·         What is the Packing for Ajwain dry extract  Manufactured by Mediocon INC?

Primary Packaging:

1. HDPE (High-Density Polyethylene) drums: HDPE drums are commonly used for packing Ajwain dry extract  Manufactured by Mediocon INCdue to their durability and resistance to moisture.

2. Aluminum or stainless steel containers: Aluminum or stainless steel containers are also used for packing Ajwain dry extract, especially for smaller quantities.

3. Glass jars or bottles: Glass jars or bottles are sometimes used for packing Ajwain dry extract, especially for high-end or specialty products.

 

Secondary Packaging:

1. Cartons or boxes: Cartons or boxes are used to protect the primary packaging and provide additional support during transportation.

2. Pouches or bags: Pouches or bags are sometimes used as secondary packaging for Ajwain dry extract, especially for smaller quantities.

 

Tertiary Packaging:

1. Pallets: Pallets are used to stack and secure cartons or boxes during transportation.

2. Shrink wrapping: Shrink wrapping is used to protect the pallets and prevent damage during transportation.

 

Specialized Packaging:

1. Nitrogen-flushed packaging: Nitrogen-flushed packaging is used to remove oxygen and prevent degradation of the Ajwain dry extract.

2. Moisture-absorbing packaging: Moisture-absorbing packaging is used to control humidity and prevent moisture from affecting the Ajwain dry extract.

3. Light-protective packaging: Light-protective packaging is used to prevent light from affecting the Ajwain dry extract.

 

Labeling and Documentation:

1. Labels: Labels are applied to the packaging to provide information about the product, including its name, ingredients, and instructions for use.

2. Certificates of Analysis (COAs): COAs are documents that provide detailed information about the product's quality, purity, and composition.

3. Safety Data Sheets (SDSs): SDSs are documents that provide information about the product's safety and handling procedures.

 

·         What is shelf life of Ajwain dry extract  Manufactured by Mediocon INC?

Typical Shelf Life:

1. 2-3 years: Ajwain dry extract  Manufactured by Mediocon INCcan typically last for 2-3 years from the date of manufacture when stored properly.

2. 1-2 years: If the extract is exposed to heat, moisture, or light, its shelf life may be reduced to 1-2 years.

 

Factors Affecting Shelf Life:

1. Moisture: High humidity can cause the extract to become rancid or develop off-flavors.

2. Light: Exposure to direct sunlight or UV light can cause the extract to degrade or become discolored.

3. Temperature: High temperatures can cause the extract to degrade or become rancid.

4. Oxygen: Exposure to oxygen can cause the extract to become rancid or develop off-flavors.

5. Contamination: Exposure to contaminants, such as dust, dirt, or microorganisms, can affect the quality and shelf life of the extract.

 

Storage Conditions:

1. Cool, dry place: Store the extract in a cool, dry place, away from direct sunlight and moisture.

2. Airtight containers: Store the extract in airtight containers, such as glass jars or plastic containers, to prevent exposure to oxygen and moisture.

3. Refrigeration: Store the extract in the refrigerator to prolong its shelf life.

 

Re-Testing and Re-Validation:

1. Regular testing: Regularly test the extract for quality, purity, and potency to ensure it remains within specifications.

2. Re-validation: Re-validate the extract's shelf life periodically, such as every 6-12 months, to ensure it remains stable and effective.

·         What should the label claim include for Ajwain dry Extract?

Mandatory Information:

1. Product name: The name of the product, including the botanical name (Trachyspermum ammi) and the part used (seeds or leaves).

2. Extract ratio: The ratio of the extract, such as 10:1 or 20:1.

3. Active compounds: The active compounds present in the extract, such as thymol, carvacrol, or limonene.

4. Net weight: The net weight of the extract in grams or milligrams.

5. Batch number: The batch number or lot number of the extract.

6. Manufacturing date: The date of manufacture of the extract.

7. Expiry date: The expiry date or shelf life of the extract.

 

Recommended Information:

1. Botanical description: A brief description of the botanical source, including the family, genus, and species.

2. Part used: The part of the plant used to prepare the extract, such as seeds or leaves.

3. Extraction method: The method used to extract the active compounds, such as solvent extraction or supercritical fluid extraction.

4. Standardization: The standardization of the extract, including the percentage of active compounds.

5. Recommended dosage: The recommended dosage of the extract, including the frequency and duration of use.

6. Contraindications: Any contraindications or warnings for use, such as pregnancy, breastfeeding, or allergies.

7. Interactions: Any potential interactions with other medications or supplements.

8. Storage conditions: The recommended storage conditions for the extract, including temperature, humidity, and light exposure.

 

Regulatory Compliance:

1. Compliance with local regulations: Ensure compliance with local regulations, such as Good Manufacturing Practice (GMP) guidelines.

2. Labeling requirements: Ensure compliance with labeling requirements, such as those specified by the FDA or EU regulations.

3. Claim substantiation: Ensure that any claims made on the label are substantiated by scientific evidence.

 

Where can Ajwain dry extract  Manufactured by Mediocon INCare procured?

 

Ajwain dry extract  Manufactured by Mediocon INCcan be procured from various sources, depending on your location and requirements. Here are some options:

1.      FOR API

 MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

 Email id:info@mediocon.com                                                  

 GST No: 27DHUPM2366D1ZZ

 

2.      For Dosage Forms :

  - Online Marketplaces: You can find Ajwain dry extract  Manufactured by Mediocon INC  products on online marketplaces like  Amazon or e-commerce websites specializing in pharmaceuticals or skincare products.

  - Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in your area for Guggal Extract product

Remember to ensure the quality and authenticity of the Ajwain dry extract  Manufactured by Mediocon INC  product, regardless of the procurement source.