Valerian Root Extract 8057-49-6 Manufacturer Exporter MEDIOCON INC

 

 Valerian  Root Extract   manufacturer by Mediocon Inc

 

·   Name:  Valerian  Root Extract  

 

·   CAS No:  8057-49-6

·   Molecular Weight: 234.33g/mol

 

·   Molecular formula: C₁₅H₂₂O₂

 

·   Synonyms:  Amantilla, Baldrian

 

·   Solubility: soluble in Water

 

·     Use :

Sleep Aid:

1. Insomnia: Valerian root extract helps regulate sleep patterns, reducing symptoms of insomnia.

2. Sleep quality: Improves sleep quality by increasing deep sleep and rapid eye movement (REM) sleep.

3. Sleep duration: Helps increase sleep duration and reduces sleep latency.

Anxiety and Stress Relief:

1. Anxiety disorders: Valerian root extract has anxiolytic effects, reducing symptoms of anxiety disorders.

2. Stress relief: Helps alleviate stress and promotes relaxation.

3. Mood enhancement: May help improve mood and reduce symptoms of depression.

Muscle Relaxation:

1. Muscle cramps: Valerian root extract helps relieve muscle cramps, spasms, and tension.

2. Restless leg syndrome: May help alleviate symptoms of restless leg syndrome.

Other Uses:

1. Menopausal symptoms: Valerian root extract may help alleviate menopausal symptoms, such as hot flashes and night sweats.

2. Digestive issues: May help soothe digestive issues, such as irritable bowel syndrome (IBS).

3. Pain relief: Valerian root extract may have analgesic and anti-inflammatory effects, providing pain relief.

 

Forms and Preparations:

1. Capsules: Valerian root extract capsules are available in various strengths and formulations.

2. Tea: Valerian root tea is a popular way to consume the extract.

3. Tinctures: Valerian root tinctures can be added to water or taken sublingually.

4. Topical creams: Valerian root extract creams can be applied topically for muscle relaxation and pain relief.

Precautions and Interactions:

1. Pregnancy and breastfeeding: Consult a healthcare professional before using Valerian root extract during pregnancy or breastfeeding.

2. Sedatives and antidepressants: Valerian root extract may interact with sedatives and antidepressants, so consult a healthcare professional before using.

3. Allergic reactions: Rarely, Valerian root extract can cause allergic reactions; discontinue use if symptoms occur.

Dosage:

1. Typical dosage: 500-1000 mg of Valerian root extract per day, 30-60 minutes before bedtime.

2. Start with a low dose: Begin with a low dose and gradually increase as needed and under medical supervision.

 

·      How is  Valerian  Root Extract   manufacturer by Mediocon Inc synthesized?

 

Extraction Methods:

1. Solvent extraction: Valerian root is extracted with a solvent, such as ethanol, methanol, or acetone, to obtain the desired compounds.

2. Steam distillation: Valerian root is steam-distilled to obtain the essential oil, which contains the volatile compounds.

3. Cold percolation: Valerian root is extracted with a solvent, such as ethanol or glycerin, at a low temperature to obtain a high-quality extract.

4. Supercritical fluid extraction (SFE): Valerian root is extracted using high-pressure carbon dioxide to obtain a solvent-free extract.

5. Enzyme-assisted extraction: Valerian root is extracted using enzymes to break down the cell walls and release the desired compounds.

 

Post-Extraction Processing:

1. Filtration: The extracted liquid is filtered to remove impurities and sediment.

2. Concentration: The filtered liquid is concentrated through evaporation, distillation, or freeze-drying to obtain a powdered or semi-solid extract.

3. Drying: The concentrated extract is dried to remove any remaining solvent or moisture.

4. Milling: The dried extract is milled into a fine powder to enhance bioavailability.

 

Quality Control:

1. Testing for purity: The extract is tested for purity, potency, and contaminants.

2. Standardization: The extract is standardized to ensure a consistent level of active compounds.

3. Stability testing: The extract is tested for stability to ensure it remains potent and effective over time.

 

Manufacturing Considerations:

1. GMP compliance: Manufacturers must comply with Good Manufacturing Practice (GMP) regulations to ensure quality and safety.

2. Equipment cleaning: Equipment must be thoroughly cleaned and sanitized to prevent contamination.

3. Personnel training: Personnel involved in the extraction and processing must be trained in GMP and quality control procedures.

 

·         What are the different  dosage Guggal Extract?

 

Oral Dosage Forms:

1. Capsules: Guggal Extractpowder or resin is filled

 into capsules for easy consumption.

2. Tablets: Guggal Extractpowder or resin is compressed into tablets, often with added excipients.

3. Powder: Guggal Extractpowder can be consumed directly or mixed with water or other beverages.

4. Liquid extract: Guggal Extractliquid extract is available in dropper bottles for sublingual administration.

 

Topical Dosage Forms:

1. Creams: Guggal Extractis mixed with creams or ointments for topical application, often for skin and wound healing.

2. Ointments: Guggal Extractis mixed with ointments for topical application, often for skin and wound healing.

3. Gels: Guggal Extractis mixed with gels for topical application, often for skin and wound healing.

 

Other Dosage Forms:

1. Resin: Guggal Extractresin can be consumed directly or mixed with water or other beverages.

2. Tinctures: Guggal Extracttinctures are available in dropper bottles for sublingual administration.

3. Suppositories: Guggal Extractsuppositories are available for rectal administration.

 

Combination Products:

1. Herbal blends: Guggal Extractis often combined with other herbs and botanicals to create blends for specific health benefits.

2. Mineral supplements: Guggal Extractis often combined with mineral supplements, such as iron or zinc, to enhance its benefits.

3. Vitamin supplements: Guggal Extractis often combined with vitamin supplements, such as vitamin C or vitamin D, to enhance its benefits.

 

·         How Valerian Root Extract Dosage Forms are prepared

Capsules:

1. Filling: Valerian root extract powder is filled into empty capsules, typically made of gelatin or vegetarian alternatives.

2. Encapsulation: The powder is mixed with excipients, such as microcrystalline cellulose, and then filled into capsules.

3. Sealing: The capsules are sealed to prevent moisture entry and contamination.

 

Tablets:

1. Granulation: Valerian root extract powder is mixed with excipients and granulated to form a uniform mixture.

2. Compression: The granulated mixture is compressed into tablets using a tablet press.

3. Coating: The tablets may be coated with a thin layer of material, such as cellulose or wax, to improve appearance and stability.

 

Softgels:

1. Mixing: Valerian root extract oil is mixed with a gelatin-based matrix and other excipients.

2. Encapsulation: The mixture is then encapsulated into softgels using a rotary die process.

3. Sealing: The softgels are sealed to prevent moisture entry and contamination.

 

Liquids:

1. Mixing: Valerian root extract is mixed with a solvent, such as ethanol or glycerin, and other excipients.

2. Filtration: The mixture is filtered to remove impurities and sediment.

3. Filling: The liquid is filled into bottles or other containers for distribution.

 

Topical Creams and Ointments:

1. Mixing: Valerian root extract is mixed with a topical base, such as petroleum jelly or coconut oil, and other excipients.

2. Blending: The mixture is blended to ensure uniformity.

3. Filling: The topical cream or ointment is filled into containers for distribution.

 

Quality Control:

1. Testing: The final product is tested for purity, potency, and contaminants.

2. Standardization: The product is standardized to ensure a consistent level of active compounds.

3. Stability testing: The product is tested for stability to ensure it remains potent and effective over time.

 

·          

·         What are the appropriate Dosage forms of Guggal Extract?

 

Oral Dosage Forms:

1. Capsules: Hard or soft gelatin capsules containing  Valerian  Root Extract   manufacturer by Mediocon Inc powder or oil.

2. Tablets: Compressed tablets containing  Valerian  Root Extract   manufacturer by Mediocon Inc powder, often combined with excipients.

3. Softgels: Soft gelatin capsules containing  Valerian  Root Extract   manufacturer by Mediocon Inc oil.

4. Powder: Loose powder containing Guggal extract, often packaged in sachets or bottles.

 

Liquid Dosage Forms:

1. Tinctures: Concentrated liquid extracts of Guggal, often containing 20-50% guggulsterones.

2. Liquid extracts: Liquid extracts of Guggal, often containing 10-30% guggulsterones.

3. Syrups: Sweetened liquid preparations containing Guggal extract.

 

Topical Dosage Forms:

1. Creams: Semi-solid preparations containing Guggal extract, often used for skin conditions.

2. Ointments: Semi-solid preparations containing Guggal extract, often used for skin conditions.

3. Gels: Clear, semi-solid preparations containing Guggal extract, often used for skin conditions.

 

Other Dosage Forms:

1. Suppositories: Solid preparations containing Guggal extract, designed for rectal administration.

2. Transdermal patches: Adhesive patches containing Guggal extract, designed for transdermal delivery.

 

Considerations:

1. Bioavailability: The dosage form should ensure optimal bioavailability of the active compounds.

2. Stability: The dosage form should ensure stability of the active compounds during storage and use.

3. Patient compliance: The dosage form should be convenient and easy to use, promoting patient compliance.

4. Regulatory compliance: The dosage form should comply with relevant regulatory requirements, such as GMP and FDA guidelines.

 

·         When should  Valerian  Root Extract   manufacturer by Mediocon Inc be taken?

 

General Recommendations:

1. Morning: Taking  Valerian  Root Extract   manufacturer by Mediocon Inc in the morning may help boost energy and support weight management throughout the day.

2. Before meals: Taking  Valerian  Root Extract   manufacturer by Mediocon Inc before meals may help support digestion and nutrient absorption.

3. At bedtime: Taking  Valerian  Root Extract   manufacturer by Mediocon Inc at bedtime may help support relaxation and reduce inflammation.

 

Specific Health Goals:

1. Weight management: Take  Valerian  Root Extract   manufacturer by Mediocon Inc 30 minutes to 1 hour before meals to support weight loss and management.

2. Cholesterol reduction: Take  Valerian  Root Extract   manufacturer by Mediocon Inc with meals to support cholesterol reduction and lipid profile improvement.

3. Inflammation reduction: Take  Valerian  Root Extract   manufacturer by Mediocon Inc at bedtime to support inflammation reduction and relaxation.

4. Digestive health: Take  Valerian  Root Extract   manufacturer by Mediocon Inc before meals to support digestion and nutrient absorption.

 

Considerations:

1. Start with a low dose: Begin with a low dose and gradually increase as needed and under medical supervision.

2. Monitor for side effects: Monitor for side effects, such as gastrointestinal upset, and adjust the timing or dosage as needed.

3. Consult a healthcare professional: Consult with a healthcare professional to determine the best timing and dosage for your specific needs.

 

Interactions with Medications:

1. Blood thinners: Take  Valerian  Root Extract   manufacturer by Mediocon Inc at least 2 hours away from blood thinners to minimize interactions.

2. Diabetes medications: Take  Valerian  Root Extract   manufacturer by Mediocon Inc at least 2 hours away from diabetes medications to minimize interactions.

3. Thyroid medications: Take  Valerian  Root Extract   manufacturer by Mediocon Inc at least 2 hours away from thyroid medications to minimize interactions

 

What are the effects And Side effects of Guggal Extract?

 

Effects of Guggal Extract:

1. Anti-inflammatory:  Valerian  Root Extract   manufacturer by Mediocon Inc has anti-inflammatory properties, which may help reduce inflammation and pain.

2. Antioxidant:  Valerian  Root Extract   manufacturer by Mediocon Inc has antioxidant properties, which may help protect against oxidative stress and cell damage.

3. Cholesterol reduction:  Valerian  Root Extract   manufacturer by Mediocon Inc may help reduce cholesterol levels and improve lipid profiles.

4. Weight management:  Valerian  Root Extract   manufacturer by Mediocon Inc may help support weight loss and management.

5. Digestive health:  Valerian  Root Extract   manufacturer by Mediocon Inc may help support digestive health and reduce symptoms of irritable bowel syndrome (IBS).

 

Side Effects of Guggal Extract:

1. Gastrointestinal upset:  Valerian  Root Extract   manufacturer by Mediocon Inc may cause gastrointestinal upset, including nausea, vomiting, diarrhea, and stomach cramps.

2. Allergic reactions: Some individuals may be allergic to Guggal extract, which can cause allergic reactions, including hives, itching, and difficulty breathing.

3. Bleeding disorders:  Valerian  Root Extract   manufacturer by Mediocon Inc may increase the risk of bleeding in individuals with bleeding disorders, such as hemophilia.

4. Diabetes:  Valerian  Root Extract   manufacturer by Mediocon Inc may lower blood sugar levels, which can be problematic for individuals with diabetes.

5. Thyroid disorders:  Valerian  Root Extract   manufacturer by Mediocon Inc may interact with thyroid medications and worsen thyroid disorders, such as hypothyroidism.

6. Kidney and liver damage: Long-term use of  Valerian  Root Extract   manufacturer by Mediocon Inc may cause kidney and liver damage in some individuals.

7. Interactions with medications:  Valerian  Root Extract   manufacturer by Mediocon Inc may interact with certain medications, including blood thinners, diabetes medications, and thyroid medications.

 

Contraindications:

1. Pregnancy and breastfeeding:  Valerian  Root Extract   manufacturer by Mediocon Inc should not be taken during pregnancy or breastfeeding, as its effects on the fetus or baby are not well understood.

2. Bleeding disorders: Individuals with bleeding disorders, such as hemophilia, should avoid taking Guggal extract.

3. Surgery:  Valerian  Root Extract   manufacturer by Mediocon Inc may increase the risk of bleeding during surgery, so it's recommended to stop taking it at least 2 weeks before surgery.

 

Precautions:

1. Start with a low dose: Begin with a low dose and gradually increase as needed and under medical supervision.

2. Monitor for side effects: Monitor for side effects, especially gastrointestinal upset, and adjust the dosage or discontinue use if necessary.

3. Consult a healthcare professional: Consult with a healthcare professional before taking Guggal extract, especially if you have any underlying medical conditions or take medications.

 

 

·         How is  Valerian  Root Extract   manufacturer by Mediocon Inc Tested Qualitatively?

Chemical Tests:

1. Alkalinity test: A small sample of  Valerian  Root Extract   manufacturer by Mediocon Inc is mixed with a few drops of hydrochloric acid (HCl). The mixture should turn yellow or orange, indicating the presence of guggulsterones.

2. Ferric chloride test: A small sample of  Valerian  Root Extract   manufacturer by Mediocon Inc is mixed with a few drops of ferric chloride (FeCl3) solution. The mixture should turn green or blue, indicating the presence of phenolic compounds.

3. Sulfuric acid test: A small sample of  Valerian  Root Extract   manufacturer by Mediocon Inc is mixed with a few drops of sulfuric acid (H2SO4). The mixture should turn reddish-brown, indicating the presence of guggulsterones.

 

Chromatographic Tests:

1. Thin Layer Chromatography (TLC): A small sample of  Valerian  Root Extract   manufacturer by Mediocon Inc is applied to a TLC plate and developed using a suitable solvent system. The plate is then visualized under UV light to detect the presence of guggulsterones.

2. High-Performance Liquid Chromatography (HPLC): A small sample of  Valerian  Root Extract   manufacturer by Mediocon Inc is injected into an HPLC system, which separates and detects the individual compounds based on their retention times and UV-Vis spectra.

 

Spectroscopic Tests:

1. Infrared (IR) Spectroscopy: A small sample of  Valerian  Root Extract   manufacturer by Mediocon Inc is analyzed using IR spectroscopy, which provides information about the molecular structure and functional groups present in the extract.

2. Nuclear Magnetic Resonance (NMR) Spectroscopy: A small sample of  Valerian  Root Extract   manufacturer by Mediocon Inc is analyzed using NMR spectroscopy, which provides information about the molecular structure and conformation of the compounds present in the extract.

 

Microscopic Tests:

1. Microscopic examination: A small sample of  Valerian  Root Extract   manufacturer by Mediocon Inc is examined under a microscope to detect the presence of any contaminants, such as dirt, dust, or other foreign particles.

 

Other Tests:

1. Loss on drying (LOD): A small sample of  Valerian  Root Extract   manufacturer by Mediocon Inc is dried to a constant weight to determine the moisture content.

2. Ash value: A small sample of  Valerian  Root Extract   manufacturer by Mediocon Inc is incinerated to determine the ash value, which indicates the presence of inorganic impurities.

 

These qualitative tests help ensure the identity, purity, and quality of Guggul extract, which is essential for its safe and effective use in various applications.

 

 

·         Which tests are performed on Valerian Root Extract?

Physical Tests:

1. Appearance: Visual inspection for color, texture, and presence of contaminants.

2. Odor: Check for any unusual or unpleasant odors.

3. Moisture content: Measure the moisture content to ensure it's within acceptable limits.

 

Chemical Tests:

1. Valerenic acid content: Measure the valerenic acid content using methods like HPLC or GC.

2. Volatile oil content: Measure the volatile oil content using methods like GC or GC-MS.

3. Heavy metal testing: Test for heavy metals like lead, mercury, arsenic, and cadmium.

4. Pesticide residue testing: Test for pesticide residues using methods like GC-MS or LC-MS.

 

Microbiological Tests:

1. Total bacterial count: Measure the total bacterial count using methods like plate count or PCR.

2. Yeasts and molds: Measure the presence of yeasts and molds using methods like plate count or PCR.

3. Pathogen testing: Test for pathogens like Salmonella, E. coli, and Staphylococcus aureus.

 

Pharmacological Tests:

1. Sedative activity: Test the sedative activity of Valerian root extract using methods like animal studies or in vitro assays.

2. Anxiolytic activity: Test the anxiolytic activity of Valerian root extract using methods like animal studies or in vitro assays.

 

Quality Control Tests:

1. Identification: Verify the identity of Valerian root extract using methods like HPLC or GC.

2. Purity: Measure the purity of Valerian root extract using methods like HPLC or GC.

3. Stability testing: Test the stability of Valerian root extract under various conditions like temperature, humidity, and light exposure.

 

Regulatory Compliance:

1. Compliance with FDA regulations: Ensure compliance with FDA regulations, including GMP (Good Manufacturing Practice) and labeling requirements.

2. Compliance with international regulations: Ensure compliance with international regulations, including EU and WHO guidelines.

 

Certifications:

1. USP (United States Pharmacopeia) certification: Obtain USP certification to ensure compliance with quality and purity standards.

2. NSF International certification: Obtain NSF International certification to ensure compliance with quality and purity standards.

3. Organic certification: Obtain organic certification to ensure compliance with organic standards.

·         What are the challenges in Manufacturing of Valerian Root Extract API?

 

Raw Material Challenges:

1. Quality and consistency: Ensuring consistent quality of raw Valerian root material, which can vary depending on source, season, and processing methods.

2. Availability and sustainability: Securing a sustainable supply of high-quality Valerian root raw material, which can be scarce and seasonal.

3. Authentication and adulteration: Verifying the authenticity of Valerian root raw material and detecting potential adulterants.

 

Extraction and Purification Challenges:

1. Extraction efficiency: Optimizing extraction methods to achieve high yields of active compounds, such as valerenic acid.

2. Purification: Developing efficient and scalable purification methods to remove impurities and achieve high-purity Valerian root extract API.

3. Scalability: Scaling up extraction and purification processes while maintaining quality and consistency.

 

Quality Control Challenges:

1. Testing and validation: Developing and validating analytical methods to test the quality and purity of Valerian root extract API.

2. Stability testing: Conducting stability testing to ensure the API remains potent and stable over time.

3. Regulatory compliance: Ensuring compliance with regulatory requirements, such as GMP (Good Manufacturing Practice) and FDA guidelines.

 

Safety and Handling Challenges:

1. Toxicity and safety: Ensuring the safe handling and processing of Valerian root extract, which can be toxic if not processed properly.

2. Allergenic potential: Assessing the allergenic potential of Valerian root extract API and developing strategies to mitigate any allergic reactions.

3. Environmental concerns: Minimizing the environmental impact of Valerian root extract manufacturing, including waste disposal and energy consumption.

 

Regulatory Challenges:

1. Regulatory framework: Navigating the regulatory framework for Valerian root extract API, which can vary by country and region.

2. Compliance with monographs: Ensuring compliance with pharmacopeial monographs and other regulatory guidelines.

3. Labeling and claims: Ensuring accurate labeling and claims for Valerian root extract API products.

 

Supply Chain Challenges:

1. Raw material sourcing: Ensuring a consistent and reliable supply of high-quality Valerian root raw material.

2. Supply chain transparency: Ensuring transparency and accountability throughout the supply chain to prevent contamination or adulteration.

3. Regulatory compliance: Ensuring compliance with regulatory requirements throughout the supply chain.

·         What are the challenges in manufacturing of Valerian Root Extract Dosage forms?

Formulation Challenges:

1. Standardization: Standardizing the extract to ensure consistent levels of active compounds, such as valerenic acid.

2. Bioavailability: Enhancing the bioavailability of Valerian root extract to ensure optimal absorption and efficacy.

3. Stability: Ensuring the stability of Valerian root extract in various dosage forms, such as capsules, tablets, and liquids.

 

Excipient Selection Challenges:

1. Compatibility: Ensuring compatibility between Valerian root extract and excipients to prevent interactions or degradation.

2. Solubility: Selecting excipients that enhance the solubility of Valerian root extract, particularly in aqueous-based dosage forms.

3. Flowability: Ensuring the flowability of Valerian root extract powder to facilitate uniform filling and capping of capsules or tablets.

 

Manufacturing Challenges:

1. Scalability: Scaling up manufacturing processes while maintaining quality and consistency.

2. Equipment design: Designing equipment that can handle the unique properties of Valerian root extract, such as its sticky and hygroscopic nature.

3. Cleaning and validation: Ensuring thorough cleaning and validation of equipment to prevent cross-contamination and ensure regulatory compliance.

 

Quality Control Challenges:

1. Testing and validation: Developing and validating analytical methods to test the quality and purity of Valerian root extract dosage forms.

2. Stability testing: Conducting stability testing to ensure the dosage forms remain potent and stable over time.

3. Regulatory compliance: Ensuring compliance with regulatory requirements, such as GMP (Good Manufacturing Practice) and FDA guidelines.

 

Packaging Challenges:

1. Moisture protection: Ensuring packaging materials protect the dosage forms from moisture, which can affect stability and potency.

2. Light protection: Ensuring packaging materials protect the dosage forms from light, which can affect stability and potency.

3. Tamper-evident packaging: Ensuring packaging is tamper-evident to prevent contamination or adulteration.

 

Supply Chain Challenges:

1. Raw material sourcing: Ensuring a consistent and reliable supply of high-quality Valerian root extract.

2. Supply chain transparency: Ensuring transparency and accountability throughout the supply chain to prevent contamination or adulteration.

3. Regulatory compliance: Ensuring compliance with regulatory requirements throughout the supply chain.

 

Cost and Pricing Challenges:

1. Raw material costs: Managing the cost of raw materials, which can fluctuate depending on market demand and supply.

2. Manufacturing costs: Managing manufacturing costs, including labor, equipment, and overhead expenses.

3. Pricing strategy: Developing a pricing strategy that balances profitability with market demand and competition.

 

 

·         What is the Packing for Valerian Root Extract?

For Powdered Valerian Root Extract:

1. HDPE (High-Density Polyethylene) drums: 25-50 kg capacity, with airtight lids to prevent moisture entry.

2. Aluminum or stainless steel containers: 1-25 kg capacity, with airtight lids to prevent moisture entry.

3. Multi-ply paper bags: 1-25 kg capacity, with airtight liners to prevent moisture entry.

 

For Liquid Valerian Root Extract:

1. HDPE or PET (Polyethylene Terephthalate) bottles: 1-25 L capacity, with tight-fitting lids to prevent leakage.

2. Glass bottles: 1-10 L capacity, with tight-fitting lids to prevent leakage.

3. Stainless steel containers: 1-25 L capacity, with airtight lids to prevent leakage.

 

For Capsules or Tablets:

1. HDPE or PET bottles: 100-1000 count capacity, with tight-fitting lids to prevent moisture entry.

2. Blister packs: 10-100 count capacity, with airtight packaging to prevent moisture entry.

3. Aluminum or stainless steel containers: 100-1000 count capacity, with airtight lids to prevent moisture entry.

 

Specialized Packing:

1. Nitrogen-flushed packing: To prevent oxidation and spoilage.

2. Vacuum-sealed packing: To prevent moisture entry and spoilage.

3. Temperature-controlled packing: To maintain a consistent temperature during storage and transportation.

 

Labeling and Documentation:

1. Product label: With product name, ingredients, dosage instructions, and warnings.

2. Certificate of Analysis (COA): With detailed information on the extract's composition, purity, and potency.

3. Material Safety Data Sheet (MSDS): With information on the safe handling, storage, and disposal of the extract.

 

Packaging Materials:

1. Food-grade materials: Ensure packaging materials are food-grade and compliant with regulatory requirements.

2. Moisture-resistant materials: Use moisture-resistant materials to prevent moisture entry and spoilage.

3. Light-resistant materials: Use light-resistant materials to prevent light exposure and spoilage.

 

·         What is shelf life Of Valerian Root  extract? 

Storage Conditions:

1. Temperature: Store in a cool, dry place with a temperature between 15°C to 25°C (59°F to 77°F).

2. Humidity: Store in a low-humidity environment, ideally below 60% relative humidity.

3. Light: Protect from direct sunlight and UV radiation.

 

Packaging:

1. Airtight containers: Store in airtight containers to prevent moisture and air from entering.

2. Tight-fitting lids: Ensure containers have tight-fitting lids to prevent contamination and moisture entry.

 

Form:

1. Powder: Valerian root extract powder typically has a shelf life of 2-3 years.

2. Liquid: Valerian root extract liquid typically has a shelf life of 1-2 years.

3. Capsules or tablets: Valerian root extract capsules or tablets typically have a shelf life of 2-3 years.

 

General Guidelines:

1. Unopened: Unopened Valerian root extract products can last for up to 3-5 years from the manufacturing date.

2. Opened: Opened Valerian root extract products should be used within 6-12 months to ensure optimal quality and potency.

 

Signs of Spoilage:

1. Off smell: A strong, unpleasant odor may indicate spoilage.

2. Mold or fungus: Visible mold or fungus growth on the surface or inside the container indicates spoilage.

3. Slimy or sticky texture: A slimy or sticky texture may indicate spoilage or contamination.

 

Quality Control:

1. Regular testing: Regularly test Valerian root extract products for quality, purity, and potency.

2. Stability testing: Conduct stability testing to ensure the product remains potent and stable over time.

3. Certification: Obtain certification from third-party organizations, such as NSF International or the National Science Foundation.

 

·         What should the label claim for  Valerian  Root Extract   manufacturer by Mediocon Inc Include?

Mandatory Information:

1. Product name: The name of the product, including the botanical name (Valeriana officinalis) and the common name (Valerian root).

2. Net weight: The net weight of the product in grams or milligrams.

3. Ingredients: A list of ingredients, including the amount of Valerian root extract, excipients, and additives.

4. Manufacturer's name and address: The name and address of the manufacturer, packer, or distributor.

5. Batch number: The batch number or lot number of the product.

6. Expiration date: The expiration date or "Best By" date of the product.

 

Recommended Information:

1. Standardization: A statement indicating the standardization of the Valerian root extract, including the percentage of valerenic acid.

2. Dosage instructions: Instructions for use, including the recommended dosage, frequency, and duration of use.

3. Warnings and precautions: Warnings and precautions for use, including potential interactions with medications, allergies, or sensitivities.

4. Storage instructions: Instructions for storing the product, including temperature, humidity, and light exposure.

5. Quality assurance: A statement indicating the quality assurance measures taken during manufacturing, including testing for heavy metals, pesticides, and other contaminants.

 

Optional Information:

1. Health benefits: Claims about the potential health benefits of Valerian root extract, including its sedative, anxiolytic, and sleep-promoting effects.

2. Clinical studies: References to clinical studies or research supporting the efficacy and safety of Valerian root extract.

3. Certifications: Logos or statements indicating certifications, such as organic, vegan, gluten-free, or non-GMO.

 

Regulatory Compliance:

1. Compliance with FDA regulations: Ensure compliance with FDA regulations, including labeling requirements and claims substantiation.

2. Compliance with DSHEA: Ensure compliance with the Dietary Supplement Health and Education Act (DSHEA), including labeling requirements and claims substantiation.

3. Compliance with international regulations: Ensure compliance with international regulations, including EU and WHO guidelines.

 

·         Where can  Valerian  Root Extract   manufacturer by Mediocon Inc are procured?

 

 Valerian  Root Extract   manufacturer by Mediocon Inc can be procured from various sources, depending on your location and requirements. Here are some options:

1.     FOR API

 MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India
 Website:  www.mediocon.com 

    Email id:info@mediocon.com       

   GST No: 27DHUPM2366D1ZZ

 

2.      For Dosage Forms :

     - Online Marketplaces: You can find Guggal Extracte products on online marketplaces like Amazon or e-       

        commerce websites specializing in pharmaceuticals or skincare products.

      - Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in             

        your area for Guggal Extracte products.

       Remember to ensure the quality and authenticity of the Guggal Extracte product, regardless of the          

        procurement source.