Adhatoda vasica extract 90063-77-7 Manufacturer Exporter MEDIOCON INC

 

Adhatoda vasica extract Manufactured by MEDIOCON INC     


 

·   Name: Adhatoda vasica extract

 

·   CAS No: 90063-77-7

 

·   Molecular Weight: 266.3g/mol

 

·   Molecular formula:   C11H12N2O

 

 ·   Synonyms:  Vasaka, Malabar nut, Adulsa, and Justicia adhatoda.

                                                    

·   Appearance:  a dark green to brownish-green powder. 

 

·   Solubility :   vasicine is soluble in organic solvents like ethanol, DMSO, and Dimethylformamide, its   solubility in water is limited.

                  

·   Use :

Adhatoda vasica, also known as Malabar nut or Vasaka, is a plant that has been used in traditional medicine for centuries. The extract of Adhatoda vasica has several uses:

Medicinal Uses

1. Respiratory issues: Adhatoda vasica extract is used to treat respiratory problems such as bronchitis, asthma, and chronic cough.

2. Expectorant: The extract helps to loosen and clear mucus from the lungs, making it easier to breathe.

3. Antimicrobial: Adhatoda vasica extract has antimicrobial properties, which can help to combat infections.

4. Anti-inflammatory: The extract has anti-inflammatory properties, which can help to reduce inflammation and alleviate symptoms.

Other Uses

1. Digestive issues: Adhatoda vasica extract may be used to treat digestive problems such as diarrhea, dysentery, and indigestion.

2. Skin conditions: The extract may be used to treat skin conditions such as eczema, acne, and dermatitis.

3. Wound healing: Adhatoda vasica extract may be used to promote wound healing and reduce the risk of infection.

Traditional Uses

1. Ayurvedic medicine: Adhatoda vasica is used in Ayurvedic medicine to treat a variety of health conditions.

2. Unani medicine: The extract is also used in Unani medicine to treat respiratory and digestive problems.

Precautions and Contraindications

1. Pregnancy and breastfeeding: Adhatoda vasica extract may not be suitable for pregnant or breastfeeding women.

2. Allergies: Some people may be allergic to Adhatoda vasica extract, so it's essential to monitor for any adverse reactions.

3. Interactions with medications: The extract may interact with certain medications, so it's crucial to consult with a healthcare professional before using it.

·      How is  Adhatoda vasica extract manufactured by MEDIOCON INC Synthesized?

 

The synthesis of Adhatoda vasica extract manufactured by MEDIOCON INC involves several steps:

 

Raw Material Collection

1. Sourcing: Adhatoda vasica plants are sourced from farms or wild collections.

2. Quality control: The plants are inspected for quality and authenticity.

 

Extraction

1. Method: The extraction method used is typically solvent-based, such as ethanol or methanol.

2. Ratio: The plant material is extracted in a specific ratio to obtain the desired concentration of bioactive compounds.

 

Purification

1. Filtration: The extract is filtered to remove impurities.

2. Concentration: The extract is concentrated using techniques such as evaporation or lyophilization.

 

Standardization

1. Marker compounds: The extract is standardized to specific marker compounds, such as vasicine or vasicinone.

2. HPLC analysis: High-performance liquid chromatography (HPLC) is used to analyze the extract's chemical composition.

 

Quality Control

1. Testing: The extract is tested for quality, purity, and potency.

2. Certification: The extract may be certified by regulatory bodies or third-party organizations.

 

Formulation

1. Blending: The extract may be blended with other ingredients to create a specific formulation.

2. Encapsulation or tableting: The extract may be encapsulated or tableted for use in dietary supplements.

 

MEDIOCON INC may have its own proprietary methods for synthesizing Adhatoda vasica extract, which may involve variations on these steps or the use of different technologies.

·   What are the different  dosage forms  of   Achyranthes  aspera extract  Manufactured  by  MEDIOCON INC?

 

The different dosage forms of Achyranthes aspera extract manufactured by MEDIOCON INC may include:

 

Solid Dosage Forms

1. Tablets: Compressed tablets containing Achyranthes aspera extract.

2. Capsules: Hard or soft gelatin capsules containing Achyranthes aspera extract.

3. Powders: Powdered Achyranthes aspera extract for oral consumption.

 

Liquid Dosage Forms

1. Liquid extracts: Liquid Achyranthes aspera extract for oral consumption.

2. Tinctures: Concentrated liquid Achyranthes aspera extract for oral consumption.

3. Syrups: Sweetened liquid Achyranthes aspera extract for oral consumption.

 

Topical Dosage Forms

1. Creams: Topical creams containing Achyranthes aspera extract.

2. Ointments: Topical ointments containing Achyranthes aspera extract.

3. Gels: Topical gels containing Achyranthes aspera extract.

 

Other Dosage Forms

1. Teas: Herbal teas containing Achyranthes aspera extract.

2. Infusions: Infusions of Achyranthes aspera extract for oral consumption.

The specific dosage forms and formulations may vary depending on the intended use, patient population, and desired therapeutic effect.

·         How Adhatoda vasica extract Manufactured by MEDIOCON INC   Dosage Forms are prepared?

 

The preparation of Adhatoda vasica extract dosage forms manufactured by MEDIOCON INC involves several steps:

 

Preparation of Raw Material

1. Collection: Adhatoda vasica plants are collected from farms or wild collections.

2. Drying: The plants are dried to remove excess moisture.

3. Grinding: The dried plants are ground into a fine powder.

 

Extraction

1. Solvent extraction: The powdered Adhatoda vasica is extracted using a solvent, such as ethanol or methanol.

2. Ratio: The plant material is extracted in a specific ratio to obtain the desired concentration of bioactive compounds.

 

Filtration and Concentration

1. Filtration: The extract is filtered to remove impurities.

2. Concentration: The extract is concentrated using techniques such as evaporation or lyophilization.

 

Formulation

1. Blending: The extract is blended with other ingredients, such as excipients or fillers.

2. Granulation: The blended mixture is granulated to create a uniform powder.

 

Dosage Form Preparation

1. Tableting: The granulated powder is compressed into tablets.

2. Capsule filling: The granulated powder is filled into capsules.

3. Liquid preparation: The extract is mixed with a liquid carrier to create a liquid dosage form.

 

Quality Control

1. Testing: The dosage forms are tested for quality, purity, and potency.

2. Certification: The dosage forms may be certified by regulatory bodies or third-party organizations.

 

Packaging and Labeling

1. Packaging: The dosage forms are packaged in suitable containers, such as bottles or blister packs.

2. Labeling: The containers are labeled with product information, dosage instructions, and other relevant details.

 

The specific preparation methods may vary depending on the dosage form and the manufacturer's proprietary processes.

 

·         What are the appropriate Dosage forms of Adhatoda vasica extract Manufactured  by  MEDIOCON   INC?

The different dosage forms of Achyranthes aspera extract manufactured by MEDIOCON INC may include:

Solid Dosage Forms

1. Tablets: Compressed tablets containing Achyranthes aspera extract.

2. Capsules: Hard or soft gelatin capsules containing Achyranthes aspera extract.

3. Powders: Powdered Achyranthes aspera extract for oral consumption.

Liquid Dosage Forms

1. Liquid extracts: Liquid Achyranthes aspera extract for oral consumption.

2. Tinctures: Concentrated liquid Achyranthes aspera extract for oral consumption.

3. Syrups: Sweetened liquid Achyranthes aspera extract for oral consumption.

Topical Dosage Forms

1. Creams: Topical creams containing Achyranthes aspera extract.

2. Ointments: Topical ointments containing Achyranthes aspera extract.

3. Gels: Topical gels containing Achyranthes aspera extract.

Other Dosage Forms

1. Teas: Herbal teas containing Achyranthes aspera extract.

2. Infusions: Infusions of Achyranthes aspera extract for oral consumption.

The specific dosage forms and formulations may vary depending on the intended use, patient population, and desired therapeutic effect.

 

·         When should Adhatoda vasica extract Manufactured by MEDIOCON INC be taken?

The timing of taking Adhatoda vasica extract manufactured by MEDIOCON INC may vary depending on the specific product and intended use. However, here are some general guidelines:

 

General Recommendations

1. With food: Taking Adhatoda vasica extract with food may help reduce stomach upset or gastrointestinal side effects.

2. In divided doses: Taking the extract in divided doses throughout the day may help maintain consistent levels of the active compounds in the body.

Specific Timing

1. Morning and evening: Taking the extract in the morning and evening may help support respiratory health and alleviate symptoms.

2. Before bedtime: Taking the extract before bedtime may help promote relaxation and improve sleep quality.

Consult a Healthcare Professional

1. Individualized advice: Consult with a healthcare professional for personalized advice on taking Adhatoda vasica extract, especially if you have underlying health conditions or are taking medications.

2. Dosage and timing: A healthcare professional can provide guidance on the optimal dosage and timing of Adhatoda vasica extract for your specific needs.

Precautions

1. Pregnancy and breastfeeding: Consult with a healthcare professional before taking Adhatoda vasica extract during pregnancy or breastfeeding.

2. Allergies and sensitivities: If you experience any adverse reactions or allergic responses, discontinue use and consult with a healthcare professional.

 

·         What are the effects And Side effects of Adhatoda  vasica extract Manufactured by MEDIOCON INC?

The effects and side effects of Adhatoda vasica extract manufactured by MEDIOCON INC may vary depending on the individual, dosage, and intended use. Here are some possible effects and side effects:

Potential Benefits

1. Respiratory relief: Adhatoda vasica extract may help alleviate respiratory issues such as bronchitis, asthma, and chronic cough.

2. Antimicrobial properties: The extract may exhibit antimicrobial properties, which can help combat infections.

3. Anti-inflammatory effects: Adhatoda vasica extract may have anti-inflammatory properties, which can help reduce inflammation and alleviate symptoms.

Possible Side Effects

1. Gastrointestinal issues: Some individuals may experience gastrointestinal side effects such as nausea, vomiting, or diarrhea.

2. Allergic reactions: Rarely, some individuals may experience allergic reactions such as hives, itching, or difficulty breathing.

3. Interactions with medications: Adhatoda vasica extract may interact with certain medications, such as blood thinners or diabetes medications.

 

Precautions and Contraindications

1. Pregnancy and breastfeeding: Consult with a healthcare professional before using Adhatoda vasica extract during pregnancy or breastfeeding.

2. Underlying health conditions: Individuals with underlying health conditions, such as kidney or liver disease, should consult with a healthcare professional before using the extract.

3. Surgery: Adhatoda vasica extract may interact with anesthesia or other medications used during surgery, so it's essential to inform your healthcare provider if you're scheduled for surgery.

Quality and Safety

1. Manufacturing quality: MEDIOCON INC's manufacturing processes and quality control measures can impact the safety and efficacy of the extract.

2. Regulatory compliance: Ensure that the product complies with relevant regulatory requirements and guidelines.

Consult a Healthcare Professional

1. Individualized advice: Consult with a healthcare professional for personalized advice on using Adhatoda vasica extract, especially if you have underlying health conditions or are taking medications.

2. Monitoring and guidance: A healthcare professional can provide guidance on monitoring for potential side effects and adjusting your treatment plan as needed.

 

 

·         How is Adhatoda  vasica  extract Manufactured by MEDIOCON  INC  Tested Qualitatively?

The qualitative testing of Adhatoda vasica extract manufactured by MEDIOCON INC involves several methods to ensure the quality and authenticity of the extract:

Physical Testing

1. Appearance: The extract is visually inspected for its appearance, color, and texture.

2. Solubility: The extract is tested for its solubility in various solvents.

Chemical Testing

1. High-Performance Liquid Chromatography (HPLC): HPLC is used to separate, identify, and quantify the bioactive compounds present in the extract.

2. Gas Chromatography-Mass Spectrometry (GC-MS): GC-MS is used to identify and quantify the volatile compounds present in the extract.

3. Thin-Layer Chromatography (TLC): TLC is used to separate and identify the bioactive compounds present in the extract.

 

Phytochemical Testing

1. Alkaloid testing: The extract is tested for the presence of alkaloids, such as vasicine and vasicinone.

2. Flavonoid testing: The extract is tested for the presence of flavonoids, such as quercetin and kaempferol.

3. Saponin testing: The extract is tested for the presence of saponins.

 

Microbial Testing

1. Microbial contamination testing: The extract is tested for microbial contamination, such as bacteria, yeast, and mold.

2. Sterility testing: The extract is tested for sterility to ensure that it is free from microorganisms.

 

Other Testing

1. Heavy metal testing: The extract is tested for heavy metal contamination, such as lead, mercury, and arsenic.

2. Pesticide residue testing: The extract is tested for pesticide residue contamination.

Quality Control

1. Batch-to-batch consistency: The extract is tested for batch-to-batch consistency to ensure that it meets the required quality standards.

2. Compliance with regulatory requirements: The extract is tested to ensure that it complies with regulatory requirements and guidelines.

 

By conducting these qualitative tests, MEDIOCON INC can ensure that their Adhatoda vasica extract meets the required quality standards and is safe for use.

 

·         Which tests are performed on Achyranthes aspera  Extract Manufactured by  MEDIOCON INC ?

The tests performed on Achyranthes aspera extract manufactured by MEDIOCON INC may include:

 

Physical Tests

1. Appearance: Visual inspection of the extract's color, texture, and appearance.

2. Solubility: Testing the extract's solubility in various solvents.

3. Moisture content: Determining the moisture content of the extract.

 

Chemical Tests

1. High-Performance Liquid Chromatography (HPLC): Separating, identifying, and quantifying the bioactive compounds present in the extract.

2. Gas Chromatography-Mass Spectrometry (GC-MS): Identifying and quantifying the volatile compounds present in the extract.

3. Thin-Layer Chromatography (TLC): Separating and identifying the bioactive compounds present in the extract.

 

Phytochemical Tests

1. Alkaloid testing: Detecting the presence of alkaloids, such as achyranthine.

2. Flavonoid testing: Detecting the presence of flavonoids, such as quercetin and kaempferol.

3. Saponin testing: Detecting the presence of saponins.

 

Microbial Tests

1. Microbial contamination testing: Detecting microbial contamination, such as bacteria, yeast, and mold.

2. Sterility testing: Ensuring the extract is free from microorganisms.

 

Heavy Metal and Pesticide Residue Tests

1. Heavy metal testing: Detecting heavy metal contamination, such as lead, mercury, and arsenic.

2. Pesticide residue testing: Detecting pesticide residue contamination.

 

Other Tests

1. pH testing: Determining the pH of the extract.

2. Ash value testing: Determining the ash value of the extract.

3. Extract value testing: Determining the extract value of the extract.

 

Quality Control Tests

1. Batch-to-batch consistency: Ensuring batch-to-batch consistency of the extract.

2. Compliance with regulatory requirements: Ensuring the extract complies with regulatory requirements and guidelines.

 

By performing these tests, MEDIOCON INC can ensure the quality, safety, and efficacy of their Achyranthes aspera extract.

·         What are the challenges in Manufacturing of Adhatoda  vasica  extract Manufactured by MEDIOCON   INC API?

The manufacturing of Adhatoda vasica extract API by MEDIOCON INC may face several challenges, including:

 

Raw Material Challenges

1. Sourcing and procurement: Ensuring a consistent supply of high-quality Adhatoda vasica plant material.

2. Variability in plant quality: Managing variations in plant quality, potency, and composition.

3. Regulatory compliance: Ensuring compliance with regulations related to plant sourcing and procurement.

 

Extraction and Purification Challenges

1. Optimizing extraction methods: Developing and optimizing extraction methods to maximize yield and quality.

2. Removing impurities: Removing impurities and contaminants from the extract.

3. Scalability: Scaling up extraction and purification processes while maintaining quality and efficiency.

 

Quality Control and Assurance Challenges

1. Establishing quality standards: Developing and implementing quality standards for the extract.

2. Testing and analysis: Conducting thorough testing and analysis to ensure the extract's quality, purity, and potency.

3. Regulatory compliance: Ensuring compliance with regulatory requirements and guidelines.

 

Manufacturing Process Challenges

1. Process optimization: Optimizing manufacturing processes to improve efficiency, yield, and quality.

2. Equipment and facility requirements: Ensuring suitable equipment and facilities for large-scale production.

3. Training and expertise: Ensuring that personnel have the necessary training and expertise to manufacture the extract.

 

Regulatory Challenges

1. Regulatory approvals: Obtaining necessary regulatory approvals and licenses.

2. Compliance with GMP guidelines: Ensuring compliance with Good Manufacturing Practices (GMP) guidelines.

3. Labeling and packaging requirements: Meeting labeling and packaging requirements for the extract.

 

Other Challenges

1. Research and development: Continuously conducting research and development to improve the extract's quality and efficacy.

2. Intellectual property protection: Protecting intellectual property related to the extract's manufacturing process and composition.

3. Market competition: Competing with other manufacturers and suppliers of Adhatoda vasica extract.

 

By addressing these challenges, MEDIOCON INC can ensure the successful manufacturing of high-quality Adhatoda vasica extract API.

 

·         What are the challenges in manufacturing of Adhatoda  vasica extract Manufactured by MEDIOCON  INC ’s Dosage forms?

The manufacturing of Adhatoda vasica extract dosage forms by MEDIOCON INC may face several challenges, including:

 

Formulation Challenges

1. Stability and compatibility: Ensuring the stability and compatibility of the extract with other ingredients in the dosage form.

2. Bioavailability and solubility: Enhancing the bioavailability and solubility of the extract to ensure optimal efficacy.

3. Excipient selection: Selecting suitable excipients that are compatible with the extract and do not affect its stability or efficacy.

 

Manufacturing Challenges

1. Scalability and cost-effectiveness: Scaling up manufacturing processes while maintaining cost-effectiveness.

2. Equipment and facility requirements: Ensuring suitable equipment and facilities for large-scale production.

3. Process optimization: Optimizing manufacturing processes to improve efficiency and reduce costs.

 

Quality Control and Assurance Challenges

1. Establishing quality standards: Developing and implementing quality standards for the dosage forms.

2. Testing and analysis: Conducting thorough testing and analysis to ensure the dosage forms' quality, purity, and potency.

3. Regulatory compliance: Ensuring compliance with regulatory requirements and guidelines.

 

Dosage Form-Specific Challenges

1. Tablet formulation: Ensuring the extract's stability and compatibility with tablet excipients.

2. Capsule formulation: Ensuring the extract's stability and compatibility with capsule shells and fillers.

3. Liquid formulation: Ensuring the extract's stability and solubility in liquid dosage forms.

 

Regulatory Challenges

1. Regulatory approvals: Obtaining necessary regulatory approvals and licenses.

2. Compliance with GMP guidelines: Ensuring compliance with Good Manufacturing Practices (GMP) guidelines.

3. Labeling and packaging requirements: Meeting labeling and packaging requirements for the dosage forms.

 

Other Challenges

1. Research and development: Continuously conducting research and development to improve the dosage forms' quality and efficacy.

2. Intellectual property protection: Protecting intellectual property related to the dosage forms' manufacturing process and composition.

3. Market competition: Competing with other manufacturers and suppliers of Adhatoda vasica extract dosage forms.

 

By addressing these challenges, MEDIOCON INC can ensure the successful manufacturing of high-quality Adhatoda vasica extract dosage forms.

 

·         What is the Packing for Adhatoda vasica extract Manufactured by MEDIOCON INC?

The packing details for Adhatoda vasica extract manufactured by MEDIOCON INC are¹:

- Packing Size: 25 Kg

- Packing Type: HDPE Cane / Blue Cane small

- Storage Conditions: Store in a cool, airtight place

 

It's worth noting that different manufacturers may have varying packing specifications. However, for MEDIOCON INC, the above details are the standard packing requirements for their Adhatoda vasica extract product. If you're looking for more information on this product or want to inquire about purchasing, I recommend contacting the manufacturer directly or visiting their official website for more details.

 

·         What is shelf life Of Adhatoda  vasica extract Manufactured by MEDIOCON INC? 

The shelf life of Adhatoda vasica extract manufactured by MEDIOCON INC isn't publicly available. However, I can provide general guidance on factors affecting the shelf life of herbal extracts like Adhatoda vasica.

 

Factors Affecting Shelf Life

- Storage conditions: Temperature, humidity, and light exposure can impact the extract's potency and stability.

- Packaging: The type of packaging material and its quality can influence the shelf life.

- Manufacturing process: The extraction method, solvent used, and quality control measures can affect the extract's stability.

 

Typical Shelf Life Range

- Herbal extracts like Adhatoda vasica typically have a shelf life ranging from 2 to 5 years, depending on the factors mentioned above.

 

To get accurate information on the shelf life of MEDIOCON INC's Adhatoda vasica extract, I recommend contacting the manufacturer directly or checking their official website for product specifications and storage guidelines.

 

 

·         What should the label claim for Adhatoda vasica extract Manufactured by MEDIOCON INC   Include?

The label claim for Adhatoda vasica extract manufactured by MEDIOCON INC should include:

Product Information

1. Product name: Adhatoda vasica extract

2. Manufacturer's name: MEDIOCON INC

3. Batch number: Unique batch number for tracking and quality control

4. Date of manufacture: Date of production

5. Expiry date: Date of expiration or shelf life

 

Ingredients and Composition

1. List of ingredients: Adhatoda vasica extract and any other ingredients used

2. Concentration or potency: Concentration or potency of the extract (e.g., 10:1, 20% vasicine)

 

Usage and Dosage

1. Recommended dosage: Recommended dosage or usage instructions

2. Route of administration: Route of administration (e.g., oral, topical)

 

Quality and Safety

1. Quality standards: Compliance with quality standards (e.g., GMP, ISO)

2. Safety warnings: Any necessary safety warnings or cautions

 

Regulatory Compliance

1. Regulatory approvals: Any relevant regulatory approvals or licenses

2. Compliance statements: Statements indicating compliance with relevant regulations (e.g., FDA, EU)

 

Additional Information

1. Storage conditions: Recommended storage conditions (e.g., temperature, humidity)

2. Handling instructions: Any special handling instructions

 

By including this information on the label, MEDIOCON INC can ensure compliance with regulatory requirements and provide customers with essential information about their Adhatoda vasica extract product.

 

·         Where can Adhatoda vasica extract Manufactured by MEDIOCON INC are procured?

Adhatoda vasica extract Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

1.      FOR API

 MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com            

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com            

 GST No: 27DHUPM2366D1ZZ

 

2.      For Dosage Forms :

     - Online Marketplaces: You can find Adhatoda vasica extract Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

 - Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in            your area for Adhatoda vasica extract Manufactured by MEDIOCON INC  products.

 Remember to ensure the quality and authenticity of the Adhatoda vasica extract Manufactured by MEDIOCON INC product, regardless of the procurement source.

 

 

   

 

 

 

 

 

 

 

 

 

                                                Thank You

 

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