Co- enzyme Q10 303-98-0 Manufacturer Exporter MEDIOCON INC

 

Co- enzyme Q10 Manufactured by MEDIOCON INC     

 

·   Name: Co- enzyme Q10

 ·   CAS No: 303-98-0. 

·   Molecular Weight: 863.34 g/mol

 ·   Molecular formula:   C₅₉H₉₀O₄

·   Synonyms:  Ubidecarenone and Ubiquinone

                                                    

·   Appearance:  Yellow to orange crystalline powder.

 

·   Solubility :   highly soluble in organic solvents and lipids, but practically insoluble in water.

 

·   Use :

Coenzyme Q10 (CoQ10) is a naturally occurring antioxidant that plays a crucial role in energy production within cells. Here are some potential uses and benefits:

Health Benefits

1. Heart Health: Supports cardiovascular health, potentially reducing blood pressure and improving heart function.

2. Energy Production: Essential for cellular energy production, potentially improving exercise performance and reducing fatigue.

3. Antioxidant Properties: Protects cells from oxidative damage, potentially reducing inflammation and promoting overall health.

Potential Uses

1. Cardiovascular Disease: May help manage conditions like heart failure, high blood pressure, and atherosclerosis.

2. Neurodegenerative Diseases: Potential benefits for conditions like Parkinson's disease, Alzheimer's disease, and multiple sclerosis.

3. Cancer Prevention: May help reduce cancer risk due to antioxidant properties.

Other Potential Benefits

1. Migraine Prevention: May help reduce migraine frequency and severity.

2. Exercise Performance: May improve exercise performance and reduce muscle damage.

3. Skin Health: Potential benefits for skin health, including reducing signs of aging.

 

It's essential to consult with a healthcare professional before taking CoQ10 supplements, especially if you have underlying medical conditions or take medications.

 

·      How is  Co- enzyme Q10 manufactured by MEDIOCON INC Synthesized?

 

Coenzyme Q10 (CoQ10) manufactured by MEDIOCON INC may be synthesized through various methods, including:

Fermentation

1. Microbial Fermentation: Using microorganisms like bacteria or yeast to produce CoQ10.

Chemical Synthesis

1. Chemical Reactions: Series of chemical reactions to synthesize CoQ10.

Extraction

1. Natural Sources: Extracting CoQ10 from natural sources like yeast or animal tissues.

Other Methods

1. Biotechnological Methods: Utilizing biotechnology to produce CoQ10 through microbial fermentation or enzymatic synthesis.

 

The specific synthesis method used by MEDIOCON INC may depend on factors like cost, efficiency, and product quality.

 

·         What are the different  dosage forms  of   Co- enzyme Q10 Manufactured  by  MEDIOCON INC?

 

Coenzyme Q10 (CoQ10) manufactured by MEDIOCON INC likely comes in various dosage forms, including¹ ²:

- Capsules: Containing CoQ10 in oil-based or powder form, available in different strengths (e.g., 30-100 mg).

- Tablets: Oral tablets with varying doses (e.g., 100-500 mg).

- Softgels: Gelatin-based softgels containing CoQ10 in oil-based form for improved bioavailability.

- Ubiquinol and Ubiquinone Forms: Available in both oxidized (Ubiquinone) and reduced (Ubiquinol) forms, with Ubiquinol considered the "active" form.

 

Dosage recommendations vary depending on individual needs and health conditions. Typical doses range from:

- 30-40 mg, thrice daily: For healthy individuals with cardiac arrhythmia or hypertension.

- 100-300 mg daily: For patients with heart conditions, such as congestive heart failure.

- Up to 1,000 mg/day or more: In some cases, under medical supervision.

 

It's essential to consult a healthcare professional to determine the best dosage form and strength for specific needs.

 

 

·         How Co- enzyme Q10 Manufactured by MEDIOCON INC   Dosage Forms are prepared?

 

The preparation of Coenzyme Q10 (CoQ10) dosage forms manufactured by MEDIOCON INC may involve:

Powder Preparation

1. Milling: Grinding CoQ10 into a fine powder.

2. Sifting: Ensuring uniform particle size.

Capsule Preparation

1. Blending: Mixing CoQ10 powder with excipients.

2. Encapsulation: Filling capsules with the blended mixture.

Tablet Preparation

1. Granulation: Creating granules from CoQ10 powder and excipients.

2. Compression: Compressing granules into tablets.

Softgel Preparation

1. Oil-Based Formulation: Mixing CoQ10 with oils.

2. Encapsulation: Filling softgels with the oil-based mixture.

Quality Control

1. Weight Variation: Ensuring uniform weight.

2. Content Uniformity: Verifying CoQ10 content consistency.

3. Dissolution Testing: Ensuring dosage forms dissolve properly.

 

The specific preparation process may vary depending on MEDIOCON INC's proprietary methods and quality standards.

 

·         What are the appropriate Dosage forms of Co- enzyme Q10 Manufactured  by  MEDIOCON   INC?

Coenzyme Q10 (CoQ10) manufactured by MEDIOCON INC comes in various dosage forms, including:

- Capsules: Containing CoQ10 in oil-based or powder form, available in different strengths.

- Tablets: Oral tablets with varying doses.

- Softgels: Gelatin-based softgels containing CoQ10 in oil-based form for improved bioavailability.

 

CoQ10 is available in two primary forms¹ ²:

- Ubiquinone: The oxidized form, which is converted to ubiquinol by the body.

- Ubiquinol: The reduced, active antioxidant form, potentially offering better bioavailability, especially for older adults or those with impaired conversion.

 

Dosage recommendations vary depending on individual needs and health conditions. Typical doses range from:

- 30-40 mg, thrice daily: For healthy individuals with cardiac arrhythmia or hypertension.

- 100-300 mg daily: For patients with heart conditions, such as congestive heart failure.

- Up to 1,000 mg/day or more: In some cases, under medical supervision.

 

It's essential to consult a healthcare professional to determine the best dosage form and strength for specific needs.

 

·         When should Co- enzyme Q10 Manufactured by MEDIOCON INC be taken?

Coenzyme Q10 (CoQ10) manufactured by MEDIOCON INC can be taken at various times, depending on individual needs and health goals. Here are some general guidelines:

With Meals

1. Improved Absorption: Taking CoQ10 with meals, especially fatty meals, may enhance absorption.

Morning or Evening

1. Consistency: Take CoQ10 at the same time every day to maintain consistent levels.

With Food

1. Reducing Gastrointestinal Side Effects: Taking CoQ10 with food may minimize potential gastrointestinal side effects.

As Directed

1. Follow Manufacturer's Instructions: Follow MEDIOCON INC's recommended dosage and timing.

2. Consult a Healthcare Professional: Consult with a healthcare professional for personalized guidance on timing and dosage.

 

The specific timing may vary depending on individual health needs and the product's intended use.

 

·         What are the effects And Side effects of  Co- enzyme Q10 Manufactured by MEDIOCON INC?

Coenzyme Q10 (CoQ10) manufactured by MEDIOCON INC may have various effects and potential side effects:

Potential Benefits

1. Antioxidant Properties: Protects cells from oxidative damage.

2. Energy Production: Supports cellular energy production.

3. Heart Health: May help manage cardiovascular conditions.

Potential Side Effects

1. Gastrointestinal Issues: Nausea, diarrhea, stomach upset.

2. Headaches: Some individuals may experience headaches.

3. Allergic Reactions: Rarely, some people may experience allergic reactions.

Interactions

1. Blood Thinners: CoQ10 may interact with blood thinners like warfarin.

2. Blood Pressure Medications: CoQ10 may interact with blood pressure medications.

Precautions

1. Pregnancy and Breastfeeding: Consult a healthcare professional before taking CoQ10 during pregnancy or breastfeeding.

2. Surgery: Stop taking CoQ10 at least 2 weeks before surgery.

 

It's essential to consult a healthcare professional before taking CoQ10, especially if you have underlying medical conditions or take medications.

·         How is Co- enzyme Q10 Manufactured by MEDIOCON  INC  Tested Qualitatively?

Coenzyme Q10 (CoQ10) manufactured by MEDIOCON INC undergoes qualitative testing to ensure its quality, purity, and potency. Here are some possible tests:

Physical Tests

1. Appearance: Visual inspection for color, texture, and consistency.

2. Melting Point: Determining the melting point to verify identity.

Chemical Tests

1. High-Performance Liquid Chromatography (HPLC): Quantifying CoQ10 content and purity.

2. Spectroscopy (UV-Vis, IR): Analyzing molecular structure.

Purity Tests

1. Impurity Profiling: Detecting and quantifying impurities.

2. Heavy Metal Analysis: Ensuring absence of heavy metals.

Microbiological Tests

1. Microbial Contamination: Testing for presence of microorganisms.

Other Tests

1. Content Uniformity: Ensuring consistent CoQ10 content.

2. Stability Testing: Verifying shelf life and stability.

 

These tests help ensure the quality and safety of CoQ10 manufactured by MEDIOCON INC.

 

·         Which tests are performed on Co- enzyme Q10 Manufactured by  MEDIOCON INC ?

Coenzyme Q10 (CoQ10) manufactured by MEDIOCON INC may undergo various tests, including:

Physical Tests

1. Appearance: Visual inspection.

2. Melting Point: Verifying identity.

Chemical Tests

1. HPLC (High-Performance Liquid Chromatography): Quantifying CoQ10 content.

2. Spectroscopy (UV-Vis, IR): Analyzing molecular structure.

Purity Tests

1. Impurity Profiling: Detecting impurities.

2. Heavy Metal Analysis: Ensuring absence of heavy metals.

Microbiological Tests

1. Microbial Contamination: Testing for microorganisms.

Quality Control Tests

1. Content Uniformity: Ensuring consistent CoQ10 content.

2. Stability Testing: Verifying shelf life.

Other Tests

1. Assay: Quantifying CoQ10 content.

2. Identification: Verifying CoQ10 identity.

 

These tests ensure the quality, purity, and potency of CoQ10.

 

·         What are the challenges in Manufacturing of Co- enzyme Q10 Manufactured by MEDIOCON   INC API?

The manufacturing of Co- enzyme Q10 as an Active Pharmaceutical Ingredient (API) by MEDIOCON INC may face several challenges:

Raw Material Challenges

1. Quality of Guava Fruits: Ensuring consistent quality of guava fruits.

2. Seasonal Variability: Managing seasonal fluctuations in guava fruit availability.

Extraction Challenges

1. Optimizing Extraction Methods: Choosing the most effective extraction method.

2. Yield and Purity: Maximizing yield and purity of bioactive compounds.

Processing Challenges

1. Drying and Stabilization: Preventing degradation of bioactive compounds.

2. Controlling Particle Size: Achieving uniform particle size.

Quality Control Challenges

1. Standardization: Ensuring consistent quality and potency.

2. Contamination Control: Preventing contamination from microorganisms or heavy metals.

Regulatory Challenges

1. Compliance with API Regulations: Meeting regulatory requirements.

2. Documentation and Record-Keeping: Maintaining detailed documentation.

 

By addressing these challenges, MEDIOCON INC can ensure the production of high-quality Co- enzyme Q10 API.

 

·         What are the challenges in manufacturing of Co- enzyme Q10 Manufactured by MEDIOCON  INC ’s Dosage forms?

Manufacturing Coenzyme Q10 (CoQ10) dosage forms by MEDIOCON INC may face challenges such as:

Formulation Challenges

1. Poor Water Solubility: CoQ10's low water solubility can affect bioavailability.

2. Stability Issues: CoQ10's susceptibility to degradation due to light, heat, or oxygen.

Manufacturing Challenges

1. Uniformity: Ensuring consistent CoQ10 content in each dosage unit.

2. Scalability: Scaling up production while maintaining quality and consistency.

Quality Control Challenges

1. Analytical Method Development: Developing and validating analytical methods for CoQ10 quantification.

2. Regulatory Compliance: Meeting regulatory requirements and standards.

Other Challenges

1. Raw Material Sourcing: Sourcing high-quality CoQ10 raw materials.

2. Cost-Effective Production: Balancing production costs with quality and efficacy.

 

Overcoming these challenges is crucial to ensure the quality and efficacy of CoQ10 dosage forms.

·         What is the Packing for Co- enzyme Q10 Manufactured by MEDIOCON INC?

The packaging for Coenzyme Q10 (CoQ10) manufactured by MEDIOCON INC may include:

Primary Packaging

1. Bottles: Glass or plastic bottles with tight-fitting lids.

2. Blister Packs: Individual dosage units in blister packs.

3. Capsules or Softgels: CoQ10 in capsule or softgel form.

Secondary Packaging

1. Cartons: Outer cartons containing bottles or blister packs.

2. Labels: Labels with product information, dosage instructions, and warnings.

Packaging Materials

1. Light-Protective Materials: To protect CoQ10 from light degradation.

2. Air-Tight Containers: To maintain product stability and freshness.

Packaging Considerations

1. Moisture Protection: Protecting CoQ10 from moisture.

2. Tamper-Evident Packaging: Ensuring packaging is tamper-evident.

 

The specific packaging design and materials may vary depending on MEDIOCON INC's requirements and regulatory standards.

 

·         What is shelf life Of Co- enzyme Q10 Manufactured by MEDIOCON INC? 

The shelf life of Coenzyme Q10 (CoQ10) manufactured by MEDIOCON INC typically ranges from 2 to 3 years from the manufacturing date, depending on storage conditions and the brand's formulation. To maximize its shelf life and potency, store CoQ10 in a cool, dry place away from direct sunlight, extreme temperatures, and moisture.

 

Factors Affecting Shelf Life:

- Storage Conditions: Keep the bottle tightly sealed when not in use to prevent air and moisture from entering.

- Expiration Date: Check the expiration date before consuming CoQ10, as its potency may decrease over time.

- Signs of Spoilage: Look out for foul odors, discoloration, or changes in texture, which can indicate CoQ10 has gone bad.¹

 

It's recommended to discard expired or spoiled CoQ10 products to ensure optimal effectiveness and safety. If the manufacturing date is not clearly labeled, it may be best to choose a product with a specified "Best By" date or contact the manufacturer for more information.

 

 

·         What should the label claim for Co- enzyme Q10 Manufactured by MEDIOCON INC   Include?

The label claim for Coenzyme Q10 (CoQ10) manufactured by MEDIOCON INC should include:

Essential Information

1. Product Name: Coenzyme Q10 or Ubiquinone/Ubiquinol.

2. Dosage Form: Capsule, tablet, softgel, etc.

3. Strength: Amount of CoQ10 per serving (e.g., 30mg, 100mg).

4. Serving Size: Recommended number of capsules/tablets per serving.

Regulatory Information

1. Manufacturing Date: Date of manufacture or batch number.

2. Expiration Date: Expiration date or shelf life.

3. Regulatory Compliance: Compliance with relevant regulatory standards (e.g., GMP, FDA).

Health Claims (if applicable)

1. Approved Health Claims: Claims related to heart health, energy production, or antioxidant properties, if approved by regulatory authorities.

Additional Information

1. Storage Instructions: Recommendations for storage conditions.

2. Cautionary Statements: Warnings for pregnant or breastfeeding women, or individuals with specific health conditions.

3. Directions for Use: Instructions for taking the product.

The label should comply with relevant regulatory requirements and standards.

 

·         Where can Co- enzyme Q10 Manufactured by MEDIOCON INC are procured?

Co- enzyme Q10 Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

1.      FOR API

 MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com           

 GST No: 27DHUPM2366D1ZZ

 

2.      For Dosage Forms :

     - Online Marketplaces: You can find Co- enzyme Q10 Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

 - Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in your area for Co- enzyme Q10 Manufactured by MEDIOCON INC products.

 Remember to ensure the quality and authenticity of the Co- enzyme Q10 Manufactured by MEDIOCON INC product, regardless of the procurement source.