Acorus Calamus Extract 84775-39-3 Manufacturer Exporter MEDIOCON INC

 

Acorus Calamus Extract  Manufactured by MEDIOCON INC     

 

·   Name: Acorus Calamus Extract

 

·   CAS No : 84775-39-3

 

 

·   Molecular Weight: NA

 

·   Molecular formula:  NA

 

·   Synonyms :   Sweet flag, bitter pepper root.

 

Appearance :   -  brown or yellowish-brown Powder or liquid.

 

Solubility : - Ethanol, methanol, and other organic solvents. Partially soluble in: Water.

 

 

·   Use :

 

Acorus calamus extract uses:

- Traditional medicine: Digestive issues, anxiety, and stress relief.

- Cognitive function: Potential benefits for memory and focus.

- Antimicrobial properties: May help combat infections.

- Anti-inflammatory properties: May help reduce inflammation.

- Aromatherapy: Used in essential oil blends for relaxation.

 

Consult a healthcare professional before using Acorus calamus extract, especially for medicinal purposes.

 

·      How is  Acorus  Calamus Extract  manufactured by MEDIOCON INC Synthesized?

·       

Acorus calamus extract synthesis:

- Solvent extraction: Using solvents like ethanol or methanol.

- Steam distillation: For essential oil extraction.

- Cold pressing: Sometimes used for extracting oils.

 

The choice of method depends on desired compounds and extract type.

 

 

·         What are the different dosage forms of Acorus  Calamus Extract  Manufactured by MEDIOCON INC?

 

Acorus calamus extract dosage forms:

- Capsules: Standardized extracts in capsule form.

- Tablets: Compressed extracts with other ingredients.

- Tinctures: Liquid extracts in alcohol or glycerin.

- Essential oil: Used in aromatherapy or topical applications.

- Powder: Dried extract powder for various uses.

Dosage forms vary depending on intended use and product formulation. Consult a healthcare professional for guidance.

 

·         How Acorus Calamus  Extract  Manufactured by MEDIOCON INC   Dosage Forms are prepared?

 

Acorus calamus extract dosage form preparation:

- Capsules: Extract powder filled into gelatin or vegetarian capsules.

- Tablets: Extract powder mixed with excipients, compressed into tablets.

- Tinctures: Extract dissolved in solvent, filtered, and bottled.

- Essential oil: Steam-distilled extract diluted in carrier oil (if needed).

Preparation involves:

- Weighing and mixing: Accurate measurement of extract and excipients.

- Formulation: Combining extract with other ingredients (if needed).

- Quality control: Testing for purity, potency, and stability.

Manufacturing processes may vary depending on the specific product and manufacturer.

 

 

 

 

·         What are the appropriate Dosage forms of Acorus Calamus Extract Manufactured  by  MEDIOCON   INC?

 

Acorus calamus extract dosage forms vary based on individual needs and health conditions. Here are some common forms:

- Powder: 125 to 500 mg, twice a day with honey, water, or milk. Maximum daily dose is 1 gram.

- Root Extract: 25 to 50 mg, twice a day with water. Maximum daily dose is 100 mg.

- Root Ash Powder: 500 to 1000 mg, twice a day with water. Maximum daily dose is 3 grams.

- Essential Oil: Used externally, diluted in carrier oil, and under professional guidance due to potential toxicity.

 

It's crucial to consult a healthcare professional before using Acorus calamus extract, especially considering its potential side effects and interactions. Certain groups, such as pregnant or breastfeeding women, individuals with bleeding disorders, and those scheduled for surgery, should exercise caution or avoid usage.

 

·         When should Acorus Calamus Extract  Manufactured by MEDIOCON INC be taken?

Acorus Calamus extract is best taken after food, according to Ayurvedic recommendations. The timing may vary depending on the specific health condition being targeted.¹

 

Dosage Forms and Timing:

 

- Vacha (Calamus) Root Powder: 125 to 500 mg, twice a day with honey, water, or milk. Maximum daily dose is 1 gram.

- Vacha (Calamus) Root Extract: 25 to 50 mg, twice a day with water. Maximum daily dose is 100 mg.

- Vacha (Calamus) Root Ash Powder: 500 to 1000 mg, twice a day with water. Maximum daily dose is 3 grams.

 

Precautions:

 

- Avoid taking Acorus Calamus extract in high doses (more than 1 gram per day) without consulting a healthcare professional, especially if you're using antihypertensive medications or have bleeding disorders.

- Individuals with increased Pitta Dosha may experience side effects like headaches.

- Pregnant or breastfeeding women should avoid using Acorus Calamus extract due to potential toxicity and carcinogenic properties associated with β-asarone content.

 

·         What are the effects And Side effects of Acorus Calamus Extract  Manufactured by MEDIOCON INC?

 

Effects of Acorus calamus extract:

- Cognitive function: May improve memory and focus.

- Anxiety and stress relief: Traditionally used for calming effects.

- Digestive issues: May help with bloating, gas, and digestion.

- Antimicrobial properties: May help combat infections.

 

Potential side effects:

- Neurotoxicity: β-asarone content may be toxic to nervous system.

- Carcinogenic potential: β-asarone may increase cancer risk.

- Allergic reactions: Skin irritation or allergic reactions possible.

- Interactions: May interact with certain medications.

 

Consult a healthcare professional before using Acorus calamus extract, especially considering potential risks and interactions.

 

·         How is Acorus Calamus Extract  Manufactured by MEDIOCON INC Tested Qualitatively?

 

Acorus calamus extract qualitative testing:

- High-Performance Liquid Chromatography (HPLC): Identifies and quantifies bioactive compounds.

- Gas Chromatography-Mass Spectrometry (GC-MS): Analyzes volatile compounds and β-asarone content.

- Thin-Layer Chromatography (TLC): Preliminary identification of compounds.

- Physicochemical analysis: Evaluates extract's physical and chemical properties.

 

These tests ensure extract quality, purity, and potency.

 

·         Which tests are performed on Acorus Calamus Extract  Manufactured by MEDIOCON INC?

Tests performed on Acorus calamus extract:

- Physicochemical tests: Evaluate appearance, solubility, moisture content, and ash value.

- Phytochemical tests: Identify presence of alkaloids, glycosides, flavonoids, and other compounds.

- Chromatographic tests: HPLC, GC-MS, TLC to analyze bioactive compounds and β-asarone content.

- Microbial contamination tests: Ensure extract's microbiological safety.

- Heavy metal analysis: Detect presence of heavy metals like lead, mercury, and arsenic.

 

These tests ensure extract quality, safety, and efficacy.

 

·         What are the challenges in Manufacturing of Acorus Calamus Extract  Manufactured by MEDIOCON   INC API?

Challenges in manufacturing Acorus calamus extract API:

- β-asarone content regulation: Ensuring compliance with regulatory limits.

- Raw material quality: Sourcing high-quality Acorus calamus roots.

- Extraction method optimization: Choosing the best extraction method.

- Standardization: Ensuring consistent extract quality.

- Regulatory compliance: Meeting GMP and regulatory requirements.

- Contamination risk: Preventing microbial and heavy metal contamination.

These challenges require careful planning, execution, and quality control.

·         What are the challenges in manufacturing of Acorus Calamus Extract  Manufactured by MEDIOCON  INC ’s Dosage forms?

 

Challenges in manufacturing Acorus calamus extract dosage forms:

- Standardization: Ensuring consistent extract quality and potency.

- Stability: Maintaining extract stability during manufacturing and storage.

- Bioavailability: Enhancing extract bioavailability for optimal efficacy.

- Regulatory compliance: Meeting GMP and regulatory requirements.

- Quality control: Ensuring extract purity, potency, and safety.

- β-asarone content control: Managing β-asarone levels within regulatory limits.

- Formulation challenges: Overcoming formulation difficulties due to extract's physicochemical properties.

 

These challenges require expertise in herbal extract manufacturing and dosage form development.

·         What is the Packing for Acorus Calamus Extract  Manufactured by MEDIOCON INC?

 

Acorus calamus extract packing:

- Containers: Airtight containers, such as HDPE bottles or aluminum foil pouches.

- Labeling: Clear labeling with product name, ingredients, dosage instructions, and storage guidelines.

- Protection from light and moisture: Packaging designed to protect the extract from light and moisture.

 

The packaging should ensure the extract's quality, stability, and safety during storage and transportation.

 

·         What is shelf life Of Acorus Calamus Extract  Manufactured by MEDIOCON INC? 

 

Acorus calamus extract shelf life:

- Typically 2-3 years: Depending on storage conditions, packaging, and formulation.

- Storage conditions: Cool, dry place, away from direct sunlight and moisture.

 

Shelf life may vary depending on the specific product and manufacturer. Always check the label or consult the manufacturer for specific storage and shelf life information.

 

·         What should the label claim for Acorus Calamus Extract  Manufactured by MEDIOCON INC Include?

 

Acorus calamus extract label claim should include:

- Product name: Acorus calamus extract or specific product name.

- Ingredients: List of ingredients, including any additives.

- Net quantity: Amount of extract in the container.

- Dosage instructions: Recommended usage and dosage.

- Storage instructions: Guidelines for storing the extract.

- Expiration date: Date indicating the extract's shelf life.

- Manufacturer information: Name and contact details of the manufacturer.

- Warning/precautions: Any relevant warnings or precautions.

The label should provide clear and accurate information to ensure safe and effective use.

·         Where can Acorus Calamus Extract  Manufactured by MEDIOCON INC are procured?

Acorus Calamus Extract  Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

1.      FOR API

 MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com           

 GST No: 27DHUPM2366D1ZZ

 

2.      For Dosage Forms :

     - Online Marketplaces: You can find Acorus Calamus Extract  Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

 - Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in your area for Acorus Calamus Extract Manufactured by MEDIOCON INC products.

 Remember to ensure the quality and authenticity of the Acorus Calamus Extract  Manufactured by MEDIOCON INC product, regardless of the procurement source.