PUNARNAVA EXTRACT. 83-46-5 MANUFATURER EXPORTER MEDIOCON INC

 

PUNARNAVA  EXTRACT.

 

·            Name: Punarnava Extract

 

·            CAS No:   83-46-5

 

 

·            Molecular Weight: NA

 

·            Molecular formula: NA

 

 

·            Synonyms  : Boerhavia diffusa

 

·             Appearance:   oval-shaped leaves with small, pink or white flowers.

 

·            Solubility:    soluble in both water and alcohol, with solubility varying depending on     

 

                              temperature

·            Use:

 

Punarnava (Boerhavia diffusa) is a herb used in Ayurvedic medicine for various purposes:

Traditional Uses

1. Diuretic: Supporting kidney function and reducing water retention.

2. Anti-inflammatory: Reducing inflammation and pain.

3. Antioxidant: Protecting against oxidative stress.

Modern Applications

1. Kidney health: Supporting kidney function.

2. Digestive health: Aiding digestion.

3. Immune system: Boosting immunity.

Forms

1. Herbal teas: Infusions.

2. Capsules: Standardized extracts.

3. Powders: Dried herb.

 

Precautions

1. Consult a healthcare professional: Before using Punarnava, especially if taking medications or having underlying health conditions.

 

·                  How is Punarnava Extract synthesized?

Punarnava extract synthesis involves:

Extraction Methods

1. Solvent extraction: Using solvents like ethanol or water.

2. Hot water extraction: Traditional method.

3. Cold pressing: Some manufacturers use cold pressing.

Purification

1. Filtration: Removing impurities.

2. Concentration: Concentrating the extract.

Standardization

1. Bioactive compounds: Standardizing to specific levels of punarnavoside,   

Flavonoids, or other compounds.

Quality Control

1. Testing: Ensuring purity, potency, and safety.

 

·                  How Punarnava Extract Dosage Forms are prepared?

 

Punarnava extract dosage forms are prepared through:

 

Dosage Form Preparation

1. Capsules: Filling capsules with standardized Punarnava extract powder.

2. Tablets: Compressing Punarnava extract powder with excipients.

3. Powders: Mixing Punarnava extract powder with other ingredients (if applicable).

4. Liquid extracts: Concentrating Punarnava extract using solvents.

 

Formulation Considerations

1. Standardization: Ensuring consistent levels of bioactive compounds.

2. Excipients selection: Choosing suitable excipients for stability and bioavailability.

3. Quality control: Testing for purity, potency, and safety.

 

Manufacturing Process

1. Blending: Mixing Punarnava extract with other ingredients (if applicable).

2. Granulation: Preparing the mixture for compression (if applicable).

3. Compression: Forming tablets or capsules.

 

·                  What are the appropriate Dosage forms of Punarnava Extract?

Appropriate dosage forms of Punarnava extract include:

 

Dosage Forms

1. Capsules: Convenient for standardized extracts.

2. Tablets: Suitable for standardized extracts.

3. Powders: Flexible dosing and easy to consume.

4. Liquid extracts: Suitable for those preferring liquid forms.

 

Considerations

1. Standardization: Ensuring consistent levels of bioactive compounds.

2. Dosage: Following recommended dosages.

 

·                  When should Punarnava Extract be taken?

 

Punarnava extract can be taken:

 

Timing

1. With meals: To aid digestion and reduce stomach upset.

2. As recommended: Follow the manufacturer's or healthcare professional's dosage instructions.

 

Purpose

1. Kidney support: Take as directed to support kidney function.

2. Digestive health: Take with meals to aid digestion.

 

Precautions

1.      Consult a healthcare professional: Before taking Punarnava extract, especially if taking medications or having underlying health conditions.

 

·                  What are the effects And Side effects of Punarnava Extract?

Punarnava extract may have:

 

Potential Effects

1. Diuretic effects: Supporting kidney function and reducing water retention.

2. Anti-inflammatory effects: Reducing inflammation and pain.

3. Antioxidant effects: Protecting against oxidative stress.

 

Potential Side Effects

1. Gastrointestinal issues: Nausea, stomach upset, or diarrhea.

2. Allergic reactions: Rarely reported.

 

Precautions

1. Consult a healthcare professional: Before taking Punarnava extract, especially if taking medications or having underlying health conditions.

2. Monitor body's response: Adjust dosage or discontinue use if side effects occur.

 

·                  How is Punarnava Extract tested qualitatively?

Punarnava extract qualitative testing involves:

 

Methods

1. HPLC (High-Performance Liquid Chromatography): Identifying and quantifying bioactive compounds like punarnavoside.

2. GC-MS (Gas Chromatography-Mass Spectrometry): Confirming compound identities.

3. Spectroscopy: Analyzing molecular structure.

 

Testing Purpose

1. Quality control: Ensuring purity, potency, and consistency.

2. Standardization: Verifying levels of bioactive compounds.

 

Parameters Tested

1. Punarnavoside content: Quantifying the primary bioactive compound.

2. Contaminants: Detecting heavy metals, pesticides, or microbial contaminants.

 

·                  Which tests are performed on Punarnava Extract?

Tests performed on Punarnava extract may include:

 

Quality Control Tests

1. HPLC (High-Performance Liquid Chromatography): To quantify bioactive compounds like punarnavoside.

2. Microbial testing: To ensure microbial safety.

3. Heavy metal testing: To check for contaminants like lead, mercury, or arsenic.

4. Pesticide residue testing: To ensure safety.

5. Physicochemical testing: To determine properties like solubility.

 

Purpose

These tests ensure the extract's quality, purity, potency, and safety.

 

·                  What are the challenges in Manufacturing of Punarnava Extract?

 

The manufacturing of Punarnava extract faces several challenges, including:

 

Challenges

1. Raw material variability: Ensuring consistent quality of Boerhavia diffusa plant material.

2. Extraction efficiency: Optimizing extraction methods for maximum yield.

3. Standardization: Ensuring consistent levels of bioactive compounds like punarnavoside.

4. Regulatory compliance: Meeting GMP and regulatory standards.

5. Contamination risk: Preventing contamination during processing.

 

Solutions

Overcoming these challenges requires expertise in herbal extract manufacturing, quality control, and regulatory compliance.

 

·                  What are the challenges in manufacturing of Punarnava Extract Dosage forms?

The manufacturing of Punarnava extract dosage forms faces several challenges, including:

 

Challenges

1. Raw material variability: Ensuring consistent quality of Punarnava extract.

2. Formulation issues: Achieving desired bioavailability and stability.

3. Standardization: Ensuring consistent levels of bioactive compounds.

4. Regulatory compliance: Meeting GMP and regulatory standards.

5. Stability and shelf-life: Maintaining product potency and quality.

 

Solutions

Overcoming these challenges requires expertise in formulation development, quality control, and regulatory compliance.

 

·                  What is the Packing for Punarnava Extract?

Punarnava extract packaging typically involves:

 

Packaging Materials

1. Bottles: Glass or plastic bottles for capsules, tablets, or powders.

2. Blister packs: For tablets or capsules.

3. Pouches: For powders or granules.

 

Packaging Considerations

1. Moisture protection: Preventing moisture absorption.

2. Light protection: Protecting from UV light.

3. Tamper-evidence: Ensuring product integrity.

 

Labeling

1. Product information: Including ingredients, dosage, and warnings.

2. Batch number: Tracking product batches.

 

 

·                  What is shelf life of Punarnava Extract?

Punarnava extract's shelf life varies depending on the manufacturer and storage conditions. Here are some general guidelines:

- Typical shelf life: 12 to 36 months

- Specific products:

    - Natural Punarnava Dry Extract: 24 months

    - Punarnava Dry Extract by S D Foods: 12 months

    - Bio Life Punarnava Extract Tab: 36 months

    - Natures Velvet Lifecare Punarnava Pure Extract: 24 months

    - Welocity Booster's Punarnava Capsules: 10 months

It's essential to check the product label or consult with the manufacturer for specific shelf life information, as it may differ depending on the product formulation and storage conditions. Proper storage in a cool, dry place can help maintain the product's potency and extend its shelf life

 

·                  What should the label claim include for Punarnava Extract?

The label claim for Punarnava extract should include:

 

Required Information

1. Product name: Clearly stating the product name.

2. Ingredients: Listing Punarnava extract and other ingredients.

3. Dosage instructions: Providing recommended dosage and usage.

4. Net quantity: Stating the net quantity of the product.

5. Batch number: Including the batch number for tracking.

6. Expiry date: Specifying the expiry date or shelf life.

7. Storage conditions: Providing storage instructions.

8. Cautionary statements: Including warnings or cautions, if applicable.

 

Optional Information

1. Standardization: Claiming standardization to specific bioactive compounds.

2. Certifications: Displaying certifications like GMP or ISO.

 

Where can Punarnava Extract are procured?

 

Punarnava Extract can be procured from various sources, depending on your location and requirements. Here are some options:

1.               FOR API

 MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com        

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

 Email id:info@mediocon.com                                                 

 GST No: 27DHUPM2366D1ZZ

 

2.               For Dosage Forms :

  - Online Marketplaces: You can find Punarnava Extract products on online marketplaces like  Amazon or e-commerce websites specializing in pharmaceuticals or skincare products.

  - Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in your area for product

Remember to ensure the quality and authenticity of the Punarnava Extract product, regardless of the procurement source.