Achyranthes aspera extract 92201-12-2 Manufacturer MEDIOCON INC

 

Achyranthes aspera extract Manufactured by MEDIOCON INC     

 

·   Name: Achyranthes aspera extract

 

·      CAS No: 92201-12-2

·   Molecular Weight: NA

 

·   Molecular formula: NA

 

·   Synonyms:  chaff-flower, prickly chaff flower, devil's horsewhip, Sanskrit -Apamarga.

 

                                                        

·   Appearance:  yellowish-brown or reddish-brown powder. 

 

·   Solubility :  soluble in Water , ethanol.

                  

·   Use :

                                                                   

Potential Benefits

1. Anti-inflammatory properties: The extract has been shown to reduce inflammation and pain in animal studies.

2. Antioxidant activity: Achyranthes aspera extract has antioxidant properties, which can help protect against oxidative stress and cell damage.

3. Antimicrobial activity: The extract has been found to exhibit antimicrobial activity against certain bacteria and fungi.

4. Cardiovascular benefits: Some studies suggest that Achyranthes aspera extract may help lower blood pressure and cholesterol levels.

 

Traditional Uses

1. Digestive issues: The plant has been traditionally used to treat digestive problems, such as constipation, diarrhea, and dyspepsia.

2. Respiratory issues: Achyranthes aspera has been used to treat respiratory problems, including bronchitis, asthma, and cough.

3. Skin conditions: The plant has been used to treat various skin conditions, including eczema, acne, and dermatitis.

 

Precautions and Contraindications

1. Pregnancy and lactation: The safety of Achyranthes aspera extract during pregnancy and lactation has not been established.

2. Allergic reactions: Some individuals may experience allergic reactions to the plant or its extracts.

3. Interactions with medications: Achyranthes aspera extract may interact with certain medications, including blood thinners and diabetes medications.

 

Regulatory Status

1. FDA: The FDA has not approved Achyranthes aspera extract for any specific health claims.

2. Traditional medicine: The plant has been used in traditional medicine for various purposes, but its efficacy and safety have not been extensively studied.

 

Label Claim

If you are considering using Achyranthes aspera extract, the label claim should include:

 

1. Product name: Achyranthes aspera extract

2. Manufacturer's name: [Manufacturer's name]

3. Address: [Manufacturer's address]

4. Country of origin: [Country of origin]

5. Description: A brief description of the product, including its botanical name and extraction method

6. Concentration: Statement of the product's concentration, including the percentage of active ingredients

7. Recommended use: Recommended use of the product, including its intended application and industry

8. Safety precautions: Safety precautions for handling and using the product, including any necessary personal protective equipment (PPE)

9. Regulatory compliance: Statement of regulatory compliance, including any relevant certifications or approvals

 

·      How is Achyranthes  aspera extract manufactured by MEDIOCON INC Synthesized?

 

Achyranthes aspera extract manufactured by MEDIOCON INC is synthesized through a process that involves¹:

- Plant Material Selection: Achyranthes aspera plants are selected and harvested for extraction.

- Extraction Methods: Various extraction methods can be employed, including:

    - Aqueous Extraction: Water is used as a solvent to extract bioactive compounds from the plant material.

    - Organic Solvent Extraction: Organic solvents like ethanol or methanol are used to extract specific compounds.

- Reduction and Capping: The extract is then reduced and capped using agents like silver nitrate to create silver nanoparticles.

- Heating and Incubation: The reaction solution is heated to facilitate the reduction and capping process, then incubated to allow the nanoparticles to form.

 

Some studies have explored the use of innovative methods for synthesizing Achyranthes aspera extract, including² ³:

- Microwave-Assisted Synthesis: This method uses microwave radiation to accelerate the extraction and synthesis process.

- Green Synthesis: This approach utilizes eco-friendly methods and materials to minimize environmental impact.

 

The synthesized extract can be used for various applications, including⁴:

- Larvicidal Activity: The extract has shown potential as a natural larvicide against certain mosquito species.

- Antimicrobial Activity: Achyranthes aspera extract has demonstrated antimicrobial properties against specific bacteria and fungi.

- Antioxidant Activity: The extract has antioxidant properties, which can help protect against oxidative stress and cell damage.

 

·   What are the different  dosage forms  of   Achyranthes aspera extract Manufactured  by  MEDIOCON INC?

 

MEDIOCON INC's Achyranthes aspera extract comes in various dosage forms, including¹ ²:

- Fresh Juice: 5-10 ml per day, divided into multiple doses.

- Kshara: 0.5-2 g per day, divided into multiple doses. Kshara is a type of alkaline substance extracted from the plant.

- Apamarg Kshara Oil: 1-3 drops, used as ear drops for ear disorders or applied externally for skin issues.

- Powder: Used in traditional Ayurvedic formulations, such as Mutrakrichantak Churna, which is used to treat urinary issues and kidney stones.

- Paste: Made from the root or leaves, applied externally to relieve pain, itching, and skin conditions.

- Leaf Paste with Sesame Oil: Consumed orally to treat excessive menstrual bleeding, with a recommended dose of 3-5 grams, twice a day.

 

It's essential to consult a healthcare professional before using any of these dosage forms, as Achyranthes aspera can interact with other medications or have adverse effects in certain individuals.

·         How Achyranthes aspera extract Manufactured by MEDIOCON INC   Dosage Forms are prepared?

The preparation of Achyranthes aspera extract dosage forms manufactured by MEDIOCON INC involves various processes, depending on the specific dosage form. Here's an overview of the preparation methods for some common dosage forms [1]:

Fresh Juice

1. Harvesting: Fresh Achyranthes aspera plants are harvested and cleaned.

2. Juicing: The plants are juiced using a mechanical juicer or blender.

3. Filtration: The juice is filtered to remove any sediment or impurities.

4. Packaging: The fresh juice is packaged in airtight containers and stored in a cool, dry place.

Kshara (Alkaline Substance)

1. Plant Material: Achyranthes aspera plants are harvested and dried.

2. Calcination: The dried plant material is calcinated at high temperatures to produce an alkaline substance (Kshara).

3. Grinding: The Kshara is ground into a fine powder.

4. Mixing: The powder is mixed with other ingredients, if required, and packaged.

Powder

1. Drying: Achyranthes aspera plants are dried using various methods, such as air drying or freeze-drying.

2. Grinding: The dried plant material is ground into a fine powder.

3. Sifting: The powder is sifted to ensure uniform particle size.

4. Packaging: The powder is packaged in airtight containers and stored in a cool, dry place.

Paste

1. Plant Material: Fresh or dried Achyranthes aspera plants are used to make a paste.

2. Grinding: The plant material is ground into a fine paste using a mortar and pestle or blender.

3. Mixing: The paste is mixed with other ingredients, if required.

4. Packaging: The paste is packaged in airtight containers and stored in a cool, dry place.

 

 

·         What are the appropriate Dosage forms of Achyranthes aspera extract Manufactured  by  MEDIOCON   INC?

The appropriate dosage forms of Achyranthes aspera extract manufactured by MEDIOCON INC may vary depending on the intended use and individual needs. Here are some common dosage forms and their typical uses [1]:

Oral Dosage Forms

1. Tablets or Capsules: 500-1000 mg per day, divided into multiple doses, for general health and wellness.

2. Powder: 1-2 teaspoons per day, mixed with water or other liquids, for digestive issues or as a dietary supplement.

3. Fresh Juice: 5-10 ml per day, divided into multiple doses, for digestive issues or as a tonic.

Topical Dosage Forms

1. Paste: Applied topically to relieve pain, itching, and skin conditions.

2. Oil: Used as ear drops for ear disorders or applied externally for skin issues.

Traditional Dosage Forms

1. Kshara (Alkaline Substance): 0.5-2 g per day, divided into multiple doses, for various health conditions.

2. Apamarg Kshara Oil: 1-3 drops, used as ear drops for ear disorders or applied externally for skin issues.

 

It's essential to consult with a healthcare professional before using any of these dosage forms, as Achyranthes aspera can interact with other medications or have adverse effects in certain individuals

 

 

·         When should Achyranthes aspera extract Manufactured by MEDIOCON INC  be taken?

The timing of taking Achyranthes aspera extract manufactured by MEDIOCON INC may vary depending on the intended use and individual needs. Here are some general guidelines [1]:

General Health and Wellness

1. Morning: Take 1-2 capsules or tablets with breakfast for general health and wellness.

2. Before Meals: Take 1-2 teaspoons of powder mixed with water or other liquids before meals to aid digestion.

Digestive Issues

1. Before Meals: Take 1-2 capsules or tablets before meals to help with digestive issues such as bloating, gas, or indigestion.

2. After Meals: Take 1-2 teaspoons of powder mixed with water or other liquids after meals to help with digestive issues.

Skin Conditions

1. Topical Application: Apply paste or oil topically to affected areas as needed to relieve pain, itching, and skin conditions.

Ear Disorders

1. Ear Drops: Use 1-3 drops of Apamarg Kshara Oil as ear drops as needed to help with ear disorders.

 

It's essential to consult with a healthcare professional before taking Achyranthes aspera extract, as it may interact with other medications or have adverse effects in certain individuals

 

 

·         What are the effects And Side effects of Achyranthes aspera extract Manufactured by MEDIOCON INC?

Achyranthes aspera extract manufactured by MEDIOCON INC may have various effects and side effects, depending on the individual and intended use. Here are some possible effects and side effects :

Effects

1. Digestive Benefits: Achyranthes aspera extract may help with digestive issues such as bloating, gas, and indigestion.

2. Anti-Inflammatory Properties: The extract may have anti-inflammatory properties, which can help with pain and inflammation.

3. Antimicrobial Properties: Achyranthes aspera extract may have antimicrobial properties, which can help with infections.

4. Antioxidant Properties: The extract may have antioxidant properties, which can help protect against oxidative stress and cell damage.

Side Effects

1. Allergic Reactions: Some individuals may experience allergic reactions, such as hives, itching, or difficulty breathing.

2. Gastrointestinal Issues: Achyranthes aspera extract may cause gastrointestinal issues such as nausea, vomiting, or diarrhea in some individuals.

3. Interactions with Medications: The extract may interact with certain medications, such as blood thinners or diabetes medications.

4. Pregnancy and Lactation: The safety of Achyranthes aspera extract during pregnancy and lactation has not been established, and it is recommended to consult with a healthcare professional before using it.

Precautions

1. Consult a Healthcare Professional: It is recommended to consult with a healthcare professional before using Achyranthes aspera extract, especially if you have any underlying medical conditions or are taking medications.

2. Dosage and Duration: Follow the recommended dosage and duration of use to minimize the risk of side effects.

3. Monitor for Side Effects: Monitor for any side effects and report them to your healthcare professional if they occur.

 

It's essential to note that the effects and side effects of Achyranthes aspera extract may vary depending on the individual and intended use. If you experience any adverse effects or have concerns, consult with a healthcare professional

 

·         How is Achyranthes aspera extract Manufactured by MEDIOCON  INC  Tested Qualitatively?

Achyranthes aspera extract manufactured by MEDIOCON INC undergoes qualitative testing to ensure its quality and purity. Here are some common qualitative tests:

Chemical Tests

1. High-Performance Liquid Chromatography (HPLC): Verifies the presence and concentration of bioactive compounds.

2. Gas Chromatography (GC): Detects and quantifies volatile compounds.

3. Mass Spectrometry (MS): Confirms the molecular structure and identity of bioactive compounds.

Physical Tests

1. Appearance: Verifies the extract's color, texture, and appearance.

2. Solubility: Tests the extract's solubility in various solvents.

3. Moisture Content: Determines the extract's moisture content to ensure stability.

Microbiological Tests

1. Microbial Contamination: Tests for the presence of microorganisms, such as bacteria, yeast, and mold.

2. Sterility: Verifies the extract's sterility, if applicable.

Other Tests

1. pH: Determines the extract's pH level to ensure stability.

2. Heavy Metal Analysis: Tests for the presence of heavy metals, such as lead, mercury, and arsenic.

 

These qualitative tests help ensure that Achyranthes aspera extract manufactured by MEDIOCON INC meets the required standards for quality, purity, and safety

 

 

·         Which tests are performed on Achyranthes aspera extract Manufactured by  MEDIOCON INC ?

Achyranthes aspera extract manufactured by MEDIOCON INC undergoes various tests to ensure its quality, purity, and safety. Here are some common tests performed on the extract:

Chemical Tests

1. High-Performance Liquid Chromatography (HPLC): Verifies the presence and concentration of bioactive compounds.

2. Gas Chromatography (GC): Detects and quantifies volatile compounds.

3. Mass Spectrometry (MS): Confirms the molecular structure and identity of bioactive compounds.

4. Fourier Transform Infrared Spectroscopy (FTIR): Identifies the functional groups and molecular structure of the extract.

Physical Tests

1. Appearance: Verifies the extract's color, texture, and appearance.

2. Solubility: Tests the extract's solubility in various solvents.

3. Moisture Content: Determines the extract's moisture content to ensure stability.

4. Particle Size Distribution: Tests the extract's particle size distribution to ensure uniformity.

Microbiological Tests

1. Microbial Contamination: Tests for the presence of microorganisms, such as bacteria, yeast, and mold.

2. Sterility: Verifies the extract's sterility, if applicable.

3. Total Plate Count: Determines the total number of microorganisms present in the extract.

Other Tests

1. pH: Determines the extract's pH level to ensure stability.

2. Heavy Metal Analysis: Tests for the presence of heavy metals, such as lead, mercury, and arsenic.

3. Pesticide Residue Analysis: Tests for the presence of pesticide residues.

4. Microbial Limit Test: Tests for the presence of specific microorganisms, such as E. coli and Salmonella.

 

·         What are the challenges in Manufacturing of Achyranthes aspera extract Manufactured by MEDIOCON   INC API?

The manufacturing of Achyro, anthes aspera extract as an Active Pharmaceutical Ingredient (API) by MEDIOCON INC may face several challenges, including [1]:

Raw Material Sourcing

1. Quality and Availability: Ensuring a consistent supply of high-quality raw materials can be challenging.

2. Seasonal Variability: The plant's growth and quality may vary depending on the season, which can impact the consistency of the extract.

Extraction and Purification

1. Optimizing Extraction Methods: Developing efficient extraction methods to obtain the desired compounds can be challenging.

2. Purification Techniques: Ensuring the purity of the extract through various purification techniques can be time-consuming and costly.

Standardization and Quality Control

1. Standardizing Extracts: Ensuring the consistency of the extract's composition and potency can be challenging.

2. Quality Control Measures: Implementing robust quality control measures to ensure the extract meets regulatory standards can be resource-intensive.

Regulatory Compliance

1. Regulatory Framework: Navigating the regulatory framework for botanical APIs can be complex and time-consuming.

2. Documentation and Record-Keeping: Maintaining detailed documentation and records to demonstrate compliance with regulatory requirements can be challenging.

Scalability and Cost-Effectiveness

1. Scaling Up Production: Scaling up production while maintaining consistency and quality can be challenging.

2. Cost-Effective Manufacturing: Ensuring that the manufacturing process is cost-effective while maintaining quality can be a challenge.

Other Challenges

1. Environmental Factors: Ensuring that the manufacturing process is environmentally friendly and sustainable can be a challenge.

2. Supply Chain Management: Managing the supply chain to ensure timely delivery of raw materials and finished products can be challenging.

 

By understanding these challenges, MEDIOCON INC can develop strategies to overcome them and ensure the successful manufacturing of Achyranthes aspera extract as an API

 

 

·         What are the challenges in manufacturing of Achyranthes aspera extract Manufactured by MEDIOCON  INC ’s Dosage forms?

The manufacturing of Achyranthes aspera extract dosage forms by MEDIOCON INC may face several challenges, including :

Formulation Challenges

1. Stability and Compatibility: Ensuring the stability and compatibility of the extract with other ingredients and excipients can be challenging.

2. Solubility and Bioavailability: Enhancing the solubility and bioavailability of the extract can be difficult.

Manufacturing Process Challenges

1. Scaling Up Production: Scaling up production while maintaining consistency and quality can be challenging.

2. Process Optimization: Optimizing the manufacturing process to ensure efficient production and minimize waste can be time-consuming.

Quality Control Challenges

1. Quality Assurance: Ensuring that the final product meets quality standards can be challenging.

2. Testing and Validation: Conducting thorough testing and validation to ensure the product's safety and efficacy can be resource-intensive.

Regulatory Challenges

1. Regulatory Compliance: Ensuring compliance with regulatory requirements can be complex and time-consuming.

2. Documentation and Record-Keeping: Maintaining detailed documentation and records to demonstrate compliance can be challenging.

Supply Chain Challenges

1. Raw Material Sourcing: Ensuring a consistent supply of high-quality raw materials can be challenging.

2. Supply Chain Management: Managing the supply chain to ensure timely delivery of raw materials and finished products can be challenging.

Other Challenges

1. Cost-Effectiveness: Ensuring that the manufacturing process is cost-effective while maintaining quality can be a challenge.

2. Environmental Sustainability: Ensuring that the manufacturing process is environmentally friendly and sustainable can be a challenge.

 

By understanding these challenges, MEDIOCON INC can develop strategies to overcome them and ensure the successful manufacturing of Achyranthes aspera extract dosage forms

 

·         What is the Packing for Achyranthes aspera extract Manufactured by MEDIOCON INC?

The packing for Achyranthes aspera extract manufactured by MEDIOCON INC isn't explicitly stated, but here's what we do know about the extract's packaging from similar manufacturers¹:

- Standard Packaging Options: Achyranthes aspera extract is commonly available in powder form, which can be packaged in various quantities, such as 25 kg or 50 kg, in fiber drums or cardboard boxes with inner liners.

- Customized Packaging: Some manufacturers offer customized packaging options to meet specific customer requirements, including different container sizes, materials, or labeling.

- Quality Control: Reputable manufacturers, like MEDIOCON INC, ensure that their products are packaged in a controlled environment to maintain quality and prevent contamination.

 

To confirm the exact packaging details for MEDIOCON INC's Achyranthes aspera extract, it's best to contact the manufacturer directly or check their official website for product specifications.

 

 

·         What is shelf life Of Achyranthes aspera extract Manufactured by MEDIOCON INC? 

The shelf life of Achyranthes aspera extract manufactured by MEDIOCON INC isn't publicly available. However, similar products from other manufacturers typically have a shelf life ranging from 2 to 5 years, depending on storage conditions and packaging.¹

 

Factors Affecting Shelf Life:

 

- Storage Conditions: Cool, dry place, away from direct sunlight and moisture.

- Packaging: Airtight containers, such as fiber drums or cardboard boxes with inner liners.

- Product Formulation: Concentration of active compounds, like saponins, and presence of preservatives.

 

To confirm the shelf life of MEDIOCON INC's Achyranthes aspera extract, it's best to contact the manufacturer directly or check their official website for product specifications.

 

·         What should the label claim for Achyranthes aspera extract Manufactured by MEDIOCON INC   Include?

The label claim for Achyranthes aspera extract manufactured by MEDIOCON INC should include the following information:

Product Information

1. Product Name: Achyranthes aspera extract

2. Manufacturer's Name: MEDIOCON INC

3. Address: Manufacturer's address

4. Country of Origin: Country where the product is manufactured

Product Description

1. Description: A brief description of the product, including its botanical name and extraction method

2. Appearance: Description of the product's appearance, including its color, texture, and form

3. Concentration: Statement of the product's concentration, including the percentage of active compounds (e.g., saponins)

Usage and Application

1. Recommended Use: Recommended use of the product, including its intended application and industry (e.g., food, cosmetics, pharmaceuticals)

2. Dosage: Recommended dosage or concentration of the product

3. Instructions for Use: Instructions for using the product, including any necessary precautions or warnings

Safety and Regulatory Information

1. Safety Precautions: Safety precautions for handling and using the product, including any necessary personal protective equipment (PPE)

2. Regulatory Compliance: Statement of regulatory compliance, including any relevant certifications or approvals (e.g., FDA, USDA, COSMOS)

3. Allergen Information: Information on potential allergens or contaminants

Storage and Handling

1. Storage Conditions: Recommended storage conditions, including temperature, humidity, and light exposure

2. Handling Precautions: Handling precautions, including any necessary precautions for transportation or storage

Quality Control and Assurance

1. Quality Control: Statement of quality control measures, including any relevant testing or certification

2. Assurance: Statement of assurance, including any relevant guarantees or warranties

 

This information is general and may vary depending on the specific product and industry. It's essential to consult with regulatory experts and industry professionals to ensure compliance with relevant regulations and standards

 

·         Where can Achyranthes aspera extract Manufactured by MEDIOCON INC are procured?

Achyranthes aspera extract Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

1.      FOR API

 MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com            

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com            

 GST No: 27DHUPM2366D1ZZ

 

2.      For Dosage Forms :

     - Online Marketplaces: You can find Achyranthes aspera extract Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

 - Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in             

   your area for Achyranthes aspera extract Manufactured by MEDIOCON INC  products.

 Remember to ensure the quality and authenticity of the Achyranthes aspera extract Manufactured by MEDIOCON INC product, regardless of the procurement source.