Bacopa Extract 93164-89-7 Manufacturer Exporter MEDIOCON INC

 

Bacopa Extract Manufactured by MEDIOCON INC     

 

·   Name: Bacopa Extract

 

·   CAS No : 93164-89-7

 

·   Molecular Weight: 536.51g/mol

 

 

·   Molecular formula:  NA

 

·   Synonyms :    Brahmi Extract

 

 

·   Appearance :    Light to dark  brown powder.

 

·   Solubility:  Partially water soluble.

 

·   Use :

 

Bacopa Extract, also known as Brahmi, has been traditionally used for:

Cognitive Function:

1. Memory enhancement: Improving memory, learning, and cognitive processing speed.

2. Neuroprotection: Potential protection against neurodegenerative diseases.

Stress Relief:

1. Anxiolytic effects: Reducing anxiety and stress.

2. Adaptogenic properties: Helping the body adapt to stress.

Other Potential Benefits:

1. Antioxidant activity: Protecting against oxidative stress.

2. Anti-inflammatory effects: Reducing inflammation.

Bacopa Extract is often used in dietary supplements, traditional medicine, and Ayurvedic practices. However, it's essential to consult with a healthcare professional before using any supplement.

 

 

How is  Bacopa Extract manufactured by MEDIOCON INC Synthesized?

 

Bacopa extract synthesis involves various methods to extract bioactive compounds from the Bacopa monnieri plant. Here's an overview of the synthesis process:

 

Extraction Methods

- Conventional Methods: Simple operations that may have drawbacks like long operation time, high energy consumption, and difficulty recovering bioactive substances.

- Innovative Approaches: Methods like¹:

    - Ultrasound-Assisted Extraction (UAE): Uses ultrasonic power to extract bioactive compounds.

    - Microwave-Assisted Extraction (MAE): Utilizes microwave energy to enhance extraction efficiency.

    - Enzymatic-Assisted Extraction (EAE): Employs enzymes to break down plant material and release bioactive compounds.

- Natural Deep Eutectic Solvents (NADES): A novel extraction method that uses natural deep eutectic solvents to extract bioactive compounds and proteins.

 

Synthesis Process

1. Drying and Grinding: Bacopa monnieri plants are dried and ground into a powder to facilitate extraction.

2. Extraction: The powdered plant material is subjected to various extraction methods, such as UAE, MAE, or EAE, using suitable solvents.

3. Purification: The extracted bioactive compounds are purified using techniques like High-Performance Liquid Chromatography (HPLC).

4. Concentration: The purified extract is then concentrated to obtain a standardized Bacopa extract, often with a specified percentage of bacosides (e.g., 20% or 50%).² ³

 

Enhancing Bacoside Synthesis

- Nanoparticle-Mediated Synthesis: Researchers have explored the use of metallic nanoparticles to regulate bacoside-A production in Bacopa monnieri plants. This approach involves synthesizing nanoparticles using Bacopa monnieri extracts, which can stimulate the production of secondary metabolites like bacoside-A.⁴

- Seed Exudates: Another study found that seed exudates from Tamarindus indica can enhance bacoside synthesis in Bacopa monnieri plants.

 

·         What are the different dosage forms of Bacopa Extract Manufactured by MEDIOCON INC?

 

Bacopa extract is available in various dosage forms, including:

 

Oral Dosage Forms:

1. Tablets: Standardized extract in tablet form.

2. Capsules: Powdered extract or oil-based extract in capsules.

3. Powders: Loose powder for mixing with food or beverages.

Other Forms:

1. Liquid Extracts: Liquid formulations for oral consumption.

2. Syrups: Sweetened liquid formulations.

Traditional Forms:

1. Ayurvedic formulations: Bacopa extract may be combined with other herbs in traditional Ayurvedic formulations.

The choice of dosage form often depends on personal preference, desired potency, and specific health goals. It's essential to follow the recommended dosage and consult with a healthcare professional before using Bacopa extract.

·         How Bacopa Extract Manufactured by MEDIOCON INC   Dosage Forms are prepared?

 

The preparation of Bacopa extract dosage forms involves several steps:

Preparation of Bacopa Extract:

1. Harvesting and drying: Bacopa monnieri plants are harvested, dried, and processed.

2. Extraction: Bioactive compounds are extracted using solvents like ethanol or water.

3. Purification: The extract is purified to remove impurities.

4. Standardization: The extract is standardized to a specific percentage of bacosides.

Dosage Form Preparation:

1. Tablets: The standardized extract is mixed with excipients and compressed into tablets.

2. Capsules: The extract is filled into capsules, often with other ingredients like fillers or lubricants.

3. Powders: The extract is powdered and packaged for use.

4. Liquid extracts: The extract is dissolved in a liquid carrier, such as water or glycerin.

Quality Control:

1. Testing for purity and potency: The final product is tested for quality and potency.

2. Labeling and packaging: The product is labeled and packaged for distribution.

The preparation process may vary depending on the manufacturer and specific dosage form.

 

·         What are the appropriate Dosage forms of Bacopa Extract Manufactured  by  MEDIOCON   INC?

 

The appropriate dosage forms of Bacopa extract include:

 

Common Dosage Forms:

1. Tablets: 100-200 mg, 1-2 times a day.

2. Capsules: 100-400 mg, 1-2 times a day.

3. Powders: 1/2 to 1 teaspoon, 1-2 times a day.

 

Considerations:

1. Standardization: Look for products standardized to 20-50% bacosides.

2. Dosage: Follow the recommended dosage on the label or consult a healthcare professional.

3. Individual needs: Dosage may vary depending on individual health goals and needs.

 

Consultation:

1. Healthcare professional: Consult with a healthcare professional before using Bacopa extract, especially if you have underlying health conditions or take medications.

 

It's essential to choose a high-quality product from a reputable manufacturer to ensure efficacy and safety.

 

·         When should Bacopa Extract Manufactured by MEDIOCON INC be taken?

Bacopa extract can be taken at various times, depending on individual goals and needs:

Recommended Timing:

1. Morning: Taking Bacopa extract in the morning may help improve cognitive function and mental clarity throughout the day.

2. With food: Taking Bacopa extract with food may help reduce stomach upset or gastrointestinal side effects.

3. Consistently: Consistency is key; take Bacopa extract at the same time every day to maintain its effects.

 

Considerations:

1. Individual tolerance: Some people may experience side effects like stomach upset or drowsiness; adjust the timing accordingly.

2. Interactions: Consult with a healthcare professional if taking other medications or supplements.

It's essential to follow the recommended dosage and consult with a healthcare professional for personalized guidance.

 

·         What are the effects And Side effects of Bacopa Extract Manufactured by MEDIOCON INC?

 

Bacopa extract has various effects and potential side effects:

 

Effects:

1. Cognitive enhancement: Improves memory, learning, and cognitive processing speed.

2. Neuroprotection: May protect against neurodegenerative diseases.

3. Anxiolytic effects: May reduce anxiety and stress.

4. Antioxidant activity: Protects against oxidative stress.

 

Potential Side Effects:

1. Gastrointestinal issues: Nausea, stomach upset, or diarrhea.

2. Dizziness or headaches: Some individuals may experience dizziness or headaches.

3. Interactions: May interact with certain medications, such as blood thinners or thyroid medications.

 

Precautions:

1. Pregnancy and breastfeeding: Consult a healthcare professional before using Bacopa extract.

2. Allergies: Individuals with allergies to Bacopa monnieri or related plants should exercise caution.

 

It's essential to consult with a healthcare professional before using Bacopa extract, especially if you have underlying health conditions or take medications.

 

 

 

·         How is Bacopa Extract Manufactured by MEDIOCON INC Tested Qualitatively?

 

Bacopa extract is tested qualitatively using various methods to ensure its quality, purity, and potency. Some common tests include:

 

Chemical Tests:

1. High-Performance Liquid Chromatography (HPLC): Analyzes the extract's chemical composition and identifies specific compounds like bacosides.

2. Spectroscopy: Techniques like UV-Vis spectroscopy or IR spectroscopy can help identify the extract's chemical structure.

 

Physical Tests:

1. Appearance: Evaluates the extract's color, texture, and appearance.

2. Solubility: Tests the extract's solubility in various solvents.

 

Biological Tests:

1. Antimicrobial testing: Assesses the extract's antimicrobial activity.

2. Antioxidant testing: Evaluates the extract's antioxidant properties.

 

Other Tests:

1. Heavy metal analysis: Tests for presence of heavy metals like lead, mercury, or arsenic.

2. Pesticide residue analysis: Tests for presence of pesticide residues.

 

These tests help ensure the quality and safety of Bacopa extract for use in dietary supplements and traditional medicine.

 

·         Which tests are performed on Bacopa Extract Manufactured by MEDIOCON INC?

Various tests are performed on Bacopa extract to ensure its quality, purity, and potency. Some common tests include:

Chemical Tests:

1. HPLC (High-Performance Liquid Chromatography): Analyzes bacoside content.

2. GC-MS (Gas Chromatography-Mass Spectrometry): Identifies and quantifies specific compounds.

Physical Tests:

1. Appearance: Evaluates color, texture, and appearance.

2. Moisture content: Determines moisture levels.

Microbiological Tests:

1. Microbial contamination: Tests for presence of microorganisms.

Contaminant Tests:

1. Heavy metal analysis: Tests for heavy metals like lead, mercury, or arsenic.

2. Pesticide residue analysis: Tests for pesticide residues.

Other Tests:

1. Potency testing: Verifies the extract's potency and efficacy.

2. Stability testing: Assesses the extract's stability over time.

These tests help ensure the quality and safety of Bacopa extract for use in dietary supplements and traditional medicine.

·         What are the challenges in Manufacturing of Bacopa Extract Manufactured by MEDIOCON   INC API?

 

The manufacturing of Bacopa extract API (Active Pharmaceutical Ingredient) poses several challenges:

 

Raw Material Challenges:

1. Quality variation: Variability in the quality of the raw material (Bacopa monnieri) can affect the final product.

2. Sourcing: Ensuring a consistent and reliable supply of high-quality raw material.

 

Extraction Challenges:

1. Extraction efficiency: Optimizing the extraction process to ensure maximum yield and quality.

2. Solvent selection: Choosing the right solvent to extract the desired bioactive compounds.

 

Purification Challenges:

1. Impurities: Removing impurities and contaminants from the extract.

2. Standardization: Standardizing the extract to ensure consistent levels of bacosides.

 

Stability Challenges:

1. Degradation: Preventing degradation of the bioactive compounds during processing and storage.

2. Shelf life: Ensuring the stability and shelf life of the final product.

 

Regulatory Challenges:

1. Compliance: Meeting regulatory requirements and standards for API manufacturing.

2. Documentation: Maintaining thorough documentation of the manufacturing process.

 

Other Challenges:

1. Scalability: Scaling up the manufacturing process while maintaining quality and consistency.

2. Cost optimization: Optimizing the manufacturing process to reduce costs while maintaining quality.

 

Addressing these challenges is crucial to ensure the quality, efficacy, and safety of the Bacopa extract API.

 

·         What are the challenges in manufacturing of Bacopa Extract Manufactured by MEDIOCON  INC ’s Dosage forms?

 

The manufacturing of Bacopa extract dosage forms poses several challenges:

Formulation Challenges:

1. Stability: Ensuring the stability of the Bacopa extract in the dosage form.

2. Bioavailability: Enhancing the bioavailability of the extract to ensure optimal efficacy.

Manufacturing Challenges:

1. Uniformity: Ensuring uniform distribution of the extract in the dosage form.

2. Scale-up: Scaling up the manufacturing process while maintaining quality and consistency.

Quality Control Challenges:

1. Standardization: Standardizing the extract and dosage form to ensure consistent levels of bacosides.

2. Testing: Conducting thorough testing to ensure quality, purity, and potency.

Regulatory Challenges:

1. Compliance: Meeting regulatory requirements and standards for dietary supplements or pharmaceuticals.

2. Labeling: Ensuring accurate labeling and claims.

Other Challenges:

1. Raw material sourcing: Sourcing high-quality Bacopa extract.

2. Cost optimization: Optimizing manufacturing costs while maintaining quality.

Addressing these challenges is crucial to ensure the quality, efficacy, and safety of Bacopa extract dosage forms.

 

 

·         What is the Packing for Bacopa Extract Manufactured by MEDIOCON INC?

 

Bacopa extract packaging varies depending on the product form and intended use:

 

Common Packaging Options:

1. Bottles: Glass or plastic bottles with caps or lids.

2. Capsules or tablets: Blister packs, bottles, or pouches.

3. Powder packets: Single-serve packets or bulk containers.

 

Packaging Considerations:

1. Light protection: Protecting the extract from light to prevent degradation.

2. Moisture control: Controlling humidity to prevent moisture absorption.

3. Tamper-evidence: Ensuring packaging is tamper-evident to maintain product integrity.

 

Labeling:

1. Product information: Including product name, dosage instructions, and ingredients.

2. Warning labels: Including warnings or cautions for potential side effects or interactions.

 

Proper packaging helps maintain the quality and potency of Bacopa extract.

 

·         What is shelf life Of Bacopa Extract Manufactured by MEDIOCON INC? 

 

The shelf life of Bacopa extract can vary depending on several factors, including:

Factors Affecting Shelf Life:

1. Storage conditions: Temperature, humidity, and light exposure.

2. Packaging: Type of packaging, such as airtight containers or sealed packets.

3. Quality of extract: Purity, potency, and processing methods.

Typical Shelf Life:

1. Raw extract: 2-5 years when stored properly.

2. Finished products: Varies depending on the product form and storage conditions.

Storage Recommendations:

1. Cool, dry place: Store in a cool, dry place, away from direct sunlight.

2. Airtight containers: Store in airtight containers to maintain freshness.

It's essential to check the product label or consult with the manufacturer for specific shelf life information.

·         What should the label claim for Bacopa Extract Manufactured by MEDIOCON INC Include?

 

The label claim for Bacopa extract should include:

Essential Information:

1. Product name: Name of the product.

2. Active ingredient: Bacopa monnieri extract or Bacopa extract.

3. Standardization: Percentage of bacosides or other active compounds.

4. Dosage instructions: Recommended dosage and usage.

5. Warning and caution statements: Potential side effects, interactions, or contraindications.

Additional Information:

1. Net weight or quantity: Amount of product in the container.

2. Manufacturer information: Name and contact information of the manufacturer.

3. Batch number and expiration date: Batch number and expiration date or shelf life.

4. Storage instructions: Recommendations for storage and handling.

The label claim should be accurate, clear, and compliant with regulatory requirements.

Regulatory Compliance

1. Comply with local regulations.

2. Ensure claims are substantiated by evidence.

Where can Bacopa Extract Manufactured by MEDIOCON INC are procured?

Bacopa Extract Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

1.      FOR API

 MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com           

 GST No: 27DHUPM2366D1ZZ

 

 

2.      For Dosage Forms :

     - Online Marketplaces: You can find Bacopa Extract Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

 - Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in your area for Bacopa Extract Manufactured by MEDIOCON INC products.

 Remember to ensure the quality and authenticity of the Bacopa Extract Manufactured by MEDIOCON INC product, regardless of the procurement source.