Bitter Orange Extract 68916-04-1 Manufacturer Exporter MEDIOCON INC

 

Bitter  Orange Extract Manufactured by MEDIOCON INC     

 

·   Name: Bitter  Orange Extract

 

·   CAS No: 68916-04-1

 

 

·   Molecular Weight: 302.29g/mol

 

·   Molecular formula:   C₉H₁₃NO₂

 

 

·   Synonyms:  Citrus aurantium extract, sour orange extract.

                                                

·   Appearance:  clear, light yellow to amber-yellow liquid with a characteristic odor.

 

 

·   Solubility :   soluble in water.

 

·   Use :

Bitter orange extract is used for various purposes:

 

1. Weight loss: Some supplements claim it aids in weight loss.

2. Digestive issues: Traditionally used to improve digestion.

3. Appetite stimulation: May increase appetite.

4. Antimicrobial properties: Some studies suggest potential benefits.

 

However, bitter orange extract can interact with medications and have side effects. Consult a healthcare professional before using it.

·      How is  Bitter  Orange Extract  manufactured by MEDIOCON INC Synthesized?

 

Bitter orange extract is typically obtained through:

 

1. Cold pressing: Extracting oil from peels.

2. Solvent extraction: Using solvents to extract bioactive compounds.

3. Hydrodistillation: Steam distillation to obtain essential oils.

 

The extraction method may vary depending on the desired compounds and intended use. Quality control ensures the extract's purity and potency.

 

·         What are the different  dosage forms  of   Bitter  Orange Extract  Manufactured  by  MEDIOCON INC?

 

Bitter orange extract comes in various dosage forms, including:

 

1. Capsules: Convenient for standardized dosing.

2. Tablets: Often combined with other ingredients.

3. Liquid extracts: Flexible dosing and potential digestive benefits.

4. Teas: Herbal teas or infusions.

5. Tinctures: Concentrated liquid extracts.

 

The choice of dosage form depends on individual preferences and needs. Consult a healthcare professional for personalized guidance.

 

·         How Bitter  Orange Extract  Manufactured by MEDIOCON INC   Dosage Forms are prepared?

 

Bitter orange extract dosage forms are prepared through various processes:

 

1. Capsules: Filling capsules with powdered extract or oil.

2. Tablets: Compressing granulated extract with excipients.

3. Liquid extracts: Mixing extract with solvents (e.g., water, glycerin).

4. Teas: Drying and packaging bitter orange peel or leaves.

5. Tinctures: Steeping bitter orange peel in solvent.

 

Quality control ensures accurate dosing, stability, and purity. Manufacturing processes follow Good Manufacturing Practices (GMPs) for safety and efficacy.

 

 

·         What are the appropriate Dosage forms of Bitter  Orange Extract  Manufactured  by  MEDIOCON   INC?

Appropriate dosage forms of Bitter Orange Extract include:

 

1. Capsules

2. Tablets

3. Liquid extracts

4. Tinctures

 

The choice of dosage form depends on individual needs, preferences, and intended use (e.g., digestive support, weight management). Consult a healthcare professional for personalized guidance.

 

 

·         When should Bitter  Orange Extract  Manufactured by MEDIOCON INC be taken?

 

Bitter orange extract is typically taken:

 

1. Before meals: To aid digestion or appetite stimulation.

2. As directed: Follow the recommended dosage and schedule.

 

Consult a healthcare professional for personalized guidance, as timing may vary depending on individual needs and health status.

 

·         What are the effects And Side effects of  Bitter  Orange Extract  Manufactured by MEDIOCON INC?

Effects of Bitter Orange Extract:

 

1. Digestive aid: Stimulates digestion and appetite.

2. Weight loss: May aid in weight loss due to stimulant properties.

3. Antimicrobial: Potential antimicrobial properties.

 

Common Side Effects:

 

1. Increased heart rate

2. High blood pressure

3. Anxiety

4. Digestive discomfort

5. Interactions with medications

Serious Side Effects (rare):

1. Cardiovascular issues

2. Seizures

Consult a healthcare professional before using bitter orange extract, especially if you have underlying health conditions or take medications.

 

 

·         How is Bitter  Orange Extract  Manufactured by MEDIOCON  INC  Tested Qualitatively?

 

Bitter orange extract is qualitatively tested using various methods, including:

 

1. High-Performance Liquid Chromatography (HPLC): Analyzes bioactive compounds like synephrine.

2. Gas Chromatography-Mass Spectrometry (GC-MS): Identifies and quantifies volatile compounds.

3. Thin-Layer Chromatography (TLC): Preliminary screening for flavonoids, alkaloids, etc.

 

These tests ensure the extract's identity, purity, and quality. Consult relevant pharmacopoeias or regulatory guidelines for specific testing requirements.

 

·         Which tests are performed on Bitter Orange Extract Manufactured by MEDIOCON INC ?

Tests performed on Bitter Orange Extract may include:

 

1. Identity tests: Confirming presence of synephrine and other bioactive compounds.

2. Purity tests: Checking for contaminants, heavy metals, and adulterants.

3. Potency tests: Quantifying synephrine and other active compounds.

4. Microbial testing: Ensuring absence of pathogens.

5. Stability testing: Evaluating shelf life and storage conditions.

 

These tests ensure quality, safety, and efficacy. Specific tests may vary depending on regulatory requirements and intended use.

 

 

·         What are the challenges in Manufacturing of Bitter  Orange Extract  Manufactured by MEDIOCON   INC API?

 

 

Challenges in manufacturing Bitter Orange Extract API (Active Pharmaceutical Ingredient) include:

 

1. Raw material variability: Quality and composition of bitter oranges can vary.

2. Standardization: Ensuring consistent levels of bioactive compounds like synephrine.

3. Extraction efficiency: Optimizing extraction methods to preserve potency.

4. Contamination risk: Preventing heavy metal, pesticide, or microbial contamination.

5. Regulatory compliance: Meeting GMP and regulatory standards.

6. Stability and shelf life: Ensuring extract stability during storage and transportation.

 

            Addressing these challenges ensures high-quality API production.

 

 

 

·         What are the challenges in manufacturing of Bitter  Orange Extract  Manufactured by MEDIOCON  INC ’s Dosage forms?

 

Challenges in manufacturing Bitter Orange Extract dosage forms include:

 

1. Standardization: Ensuring consistent levels of bioactive compounds.

2. Stability: Maintaining extract potency during formulation and storage.

3. Compatibility: Ensuring compatibility with excipients and packaging.

4. Content uniformity: Achieving uniform distribution of extract in dosage forms.

5. Regulatory compliance: Meeting GMP and regulatory requirements.

6. Quality control: Ensuring accurate labeling and quality assurance.

 

Overcoming these challenges ensures safe and effective dosage forms.

 

 

·         What is the Packing for Bitter  Orange Extract  Manufactured by MEDIOCON INC?

 

Bitter Orange Extract packaging typically includes:

 

1. Tight-fitting containers: Protecting from moisture and light.

2. Airtight containers: Preventing oxidation and degradation.

3. Labeling: Including storage instructions, expiration date, and ingredients.

4. Protective packaging: Using materials like amber glass or HDPE to shield from light.

 

Packaging ensures stability, potency, and safety of the extract.

 

 

 

·         What is shelf life Of Bitter  Orange Extract  Manufactured by MEDIOCON INC? 

The shelf life of Bitter Orange Extract varies depending on:

 

1. Storage conditions: Temperature, humidity, and light exposure.

2. Packaging: Quality and type of container.

3. Formulation: Type of extract (e.g., powder, liquid).

 

Typically, shelf life ranges from 1-3 years. Check the product label or manufacturer's guidelines for specific information.

 

 

·         What should the label claim for Bitter  Orange Extract  Manufactured by MEDIOCON INC   Include?

 

The label claim for Bitter Orange Extract should include:

 

1. Active ingredient: Bitter Orange Extract

2. Standardization: Levels of bioactive compounds (e.g., synephrine)

3. Dosage instructions: Recommended serving size

4. Storage conditions: Temperature, humidity, and light exposure guidelines

5. Expiration date: Manufacturing date and expiration date

6. Manufacturer information: Name and contact details

7. Warning statements: Potential interactions or side effects

 

             Accurate labeling ensures safe and effective use.

 

 

·         Where can Bitter  Orange Extract  Manufactured by MEDIOCON INC are procured?

Bitter Orange Extract Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

1.      FOR API

 MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com           

 GST No: 27DHUPM2366D1ZZ

 

2.      For Dosage Forms :

     - Online Marketplaces: You can find Bitter Orange Extract Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

 - Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in your area for Bitter Orange Extract Manufactured by MEDIOCON INC products.

 Remember to ensure the quality and authenticity of the Bitter Orange Extract Manufactured by MEDIOCON INC product, regardless of the procurement source.