Calcium Succinate 159389-75-0 Manufacturer Exporter MEDIOCON INC

 

Calcium Succinate  Manufactured by MEDIOCON INC     

 

·   Name: Calcium Succinate

 

·      CAS No: 159389-75-0

 

 

·   Molecular Weight: 156.15g/mol

 

·   Molecular formula: C₄H₄CaO₄

 

·   Synonyms: Succinic acid calcium salt.

 

                                                        

·   Appearance: A fine white powder. 

 

·   Solubility :   Slightly soluble in Water.

                  

·   Use :

                                                                   

Calcium Succinate is a compound used in various applications:

 

Pharmaceutical Applications:

1. Calcium supplement: Used to treat or prevent calcium deficiency.

2. Buffering agent: Used in pharmaceutical formulations to maintain pH stability.

 

Food Industry:

1. Food additive: Used as an acidity regulator or stabilizer in food products.

2. Nutritional supplement: Added to food products to enhance calcium content.

 

Other Applications:

1. Cosmetics: Used in some cosmetic products for its potential skin benefits.

2. Industrial applications: Used in various industrial processes, such as paper manufacturing.

 

The specific use of Calcium Succinate depends on its properties and the desired outcome in a particular application.

 

·      How is Calcium  Succinate  extract manufactured by MEDIOCON INC Synthesized?

 

Calcium Succinate is typically synthesized through chemical reactions rather than extraction from plants. Here's a general overview:

 

Synthesis:

1. Reaction of Succinic Acid and Calcium Salt: Succinic acid reacts with a calcium salt, such as calcium hydroxide or calcium carbonate, to form Calcium Succinate.

2. Neutralization Reaction: The reaction involves neutralizing succinic acid with a calcium base, resulting in the formation of Calcium Succinate.

 

Purification:

1. Crystallization: The resulting Calcium Succinate can be purified through crystallization.

2. Filtration: The crystals are filtered and washed to remove impurities.

 

Applications:

1. Pharmaceuticals: Calcium Succinate is used as a calcium supplement or excipient in pharmaceutical formulations.

2. Food Industry: It may be used as a food additive or nutritional supplement.

 

The specific synthesis method may vary depending on the desired purity, yield, and application of Calcium Succinate.

 

·   What are the different  dosage forms  of   Calcium Succinate  Manufactured  by  MEDIOCON INC?

 

Calcium Succinate can be formulated into various dosage forms, including:

 

Oral Dosage Forms:

1. Tablets: Compressed tablets containing Calcium Succinate.

2. Capsules: Hard or soft gelatin capsules filled with Calcium Succinate powder.

3. Powders: Powdered form of Calcium Succinate for oral administration.

 

Other Dosage Forms:

1. Suspensions: Liquid suspensions containing Calcium Succinate particles.

2. Granules: Granular form of Calcium Succinate for oral administration.

 

The choice of dosage form depends on factors such as:

Factors Influencing Dosage Form:

1. Desired release profile: Immediate release or sustained release.

2. Patient needs: Ease of administration, dosing frequency.

3. Formulation requirements: Stability, bioavailability.

The specific dosage form and formulation will depend on the intended use and requirements of the product.

 

 

·         How Calcium Succinate  Manufactured by MEDIOCON INC   Dosage Forms are prepared?

 

The preparation of Calcium Succinate dosage forms involves several steps:

 

Tablet Preparation:

1. Weighing and mixing: Accurately weigh Calcium Succinate and excipients, then mix uniformly.

2. Granulation: Granulate the mixture to improve flowability and compressibility.

3. Compression: Compress the granules into tablets using a tablet press.

 

Capsule Preparation:

1. Weighing and mixing: Accurately weigh Calcium Succinate and excipients, then mix uniformly.

2. Filling: Fill hard gelatin capsules with the powder mixture.

3. Sealing: Seal the capsules to prevent powder leakage.

 

Powder Preparation:

1. Weighing and mixing: Accurately weigh Calcium Succinate and excipients, then mix uniformly.

2. Packaging: Package the powder in suitable containers, such as sachets or bottles.

 

Quality Control:

1. Assay: Verify the amount of Calcium Succinate in the dosage form.

2. Content uniformity: Ensure uniform distribution of Calcium Succinate.

3. Physical properties: Evaluate tablet hardness, friability, or capsule integrity.

 

The specific preparation method may vary depending on the dosage form and formulation requirements.

 

·         What are the appropriate Dosage forms of Calcium Succinate  Manufactured  by  MEDIOCON   INC?

The appropriate dosage forms of Calcium Succinate depend on the intended use and patient needs. Common dosage forms include:

 

Oral Dosage Forms:

1. Tablets: Suitable for patients who require a fixed dose and can swallow tablets.

2. Capsules: Suitable for patients who have difficulty swallowing tablets or require a specific release profile.

3. Powders: Suitable for patients who require a flexible dose or have difficulty swallowing solid dosage forms.

 

Considerations:

1. Patient age and ability: Choose dosage forms that are easy to administer and swallow.

2. Dose flexibility: Consider dosage forms that allow for flexible dosing.

3. Release profile: Choose dosage forms that provide the desired release profile (e.g., immediate release or sustained release).

 

           The choice of dosage form should be based on individual patient needs and the specific       

           requirements of the product.     

 

·         When should Calcium Succinate  Manufactured by MEDIOCON INC  be taken?

Calcium Succinate can be taken:

 

Timing:

1. With meals: Taking Calcium Succinate with meals can help enhance absorption and reduce gastrointestinal side effects.

2. As directed by a healthcare provider: Follow the recommended dosage and timing instructions provided by a healthcare provider or the product label.

 

Considerations:

1. Stomach upset: Taking Calcium Succinate with food can help minimize stomach upset or gastrointestinal side effects.

2. Interactions: Be aware of potential interactions with other medications or nutrients.

It's essential to consult with a healthcare provider for personalized advice on taking Calcium Succinate.

 

·         What are the effects And Side effects of Calcium Succinate  Manufactured by MEDIOCON INC?

Calcium Succinate can have various effects and potential side effects:

 

Effects:

1. Calcium supplementation: Helps maintain bone health and supports muscle function.

2. Therapeutic benefits: May be used to treat conditions related to calcium deficiency.

 

Potential Side Effects:

1. Gastrointestinal issues: Nausea, vomiting, constipation, or stomach upset.

2. Allergic reactions: Rarely, some individuals may experience allergic reactions.

 

Interactions:

1. Medications: May interact with certain medications, such as antibiotics or thyroid medications.

2. Nutrients: May interact with other nutrients, such as iron or zinc.

 

Precautions:

1. Pregnancy and lactation: Consult a healthcare provider before taking Calcium Succinate during pregnancy or breastfeeding.

2. Kidney or heart conditions: Individuals with kidney or heart conditions should consult a healthcare provider before taking Calcium Succinate.

 

It's essential to consult with a healthcare provider for personalized advice on taking Calcium Succinate.

 

 

·         How is Calcium Succinate  Manufactured by MEDIOCON  INC  Tested Qualitatively?

Calcium Succinate can be tested qualitatively using various analytical techniques:

 

Chemical Tests:

1. Infrared Spectroscopy (IR): Identifies the molecular structure of Calcium Succinate.

2. Precipitation reactions: Tests for the presence of calcium or succinate ions.

 

Instrumental Tests:

1. High-Performance Liquid Chromatography (HPLC): Separates and detects succinate ions.

2. Atomic Absorption Spectroscopy (AAS): Measures the amount of calcium present.

 

Physical Tests:

1. Melting point determination: Determines the melting point of Calcium Succinate.

2. Solubility tests: Evaluates the solubility of Calcium Succinate in various solvents.

 

These tests help ensure the identity, purity, and quality of Calcium Succinate.

 

·         Which tests are performed on Calcium Succinate  Manufactured by  MEDIOCON INC ?

 

Calcium Succinate undergoes various tests to ensure its quality, purity, and potency. Some common tests include:

 

Physical Tests:

1. Appearance: Verifies the physical appearance, such as color and texture.

2. Solubility: Tests the solubility of Calcium Succinate in various solvents.

 

Chemical Tests:

1. Assay: Measures the amount of calcium and succinate present.

2. pH: Determines the pH of the solution.

 

Instrumental Tests:

1. High-Performance Liquid Chromatography (HPLC): Separates and detects succinate ions.

2. Atomic Absorption Spectroscopy (AAS): Measures the amount of calcium present.

 

Quality Control Tests:

1. Impurity profiling: Detects and quantifies impurities.

2. Microbial testing: Ensures the product meets microbial safety standards.

 

These tests help ensure the quality and safety of Calcium Succinate for various applications.

 

·         What are the challenges in Manufacturing of Calcium Succinate  Manufactured by MEDIOCON   INC API?

The manufacturing of Calcium Succinate API (Active Pharmaceutical Ingredient) poses several challenges:

 

Chemical Challenges:

1. Synthesis complexity: The synthesis process requires careful control to ensure purity and yield.

2. Impurity control: Controlling impurities is crucial to ensure the quality and safety of the API.

 

Physical Challenges:

1. Particle size control: Controlling particle size is important for uniformity and bioavailability.

2. Hygroscopicity: Calcium Succinate may be hygroscopic, requiring careful handling and storage.

 

Process Challenges:

1. Process optimization: Optimizing the manufacturing process is crucial to ensure consistency and quality.

2. Scale-up: Scaling up the manufacturing process while maintaining quality and consistency can be challenging.

 

Regulatory Challenges:

1. Compliance with GMP: Ensuring compliance with Good Manufacturing Practice (GMP) regulations is essential.

2. Documentation and validation: Maintaining detailed documentation and validating the manufacturing process are critical.

 

Addressing these challenges is essential to ensure the production of high-quality Calcium Succinate API.

 

·         What are the challenges in manufacturing of Calcium Succinate  Manufactured by MEDIOCON  INC ’s Dosage forms?

The manufacturing of Calcium Succinate dosage forms poses several challenges:

 

Formulation Challenges:

1. Stability: Ensuring the stability of Calcium Succinate in various dosage forms.

2. Compatibility: Ensuring compatibility with excipients and other ingredients.

 

Manufacturing Challenges:

1. Uniformity: Ensuring uniform distribution of Calcium Succinate in the dosage form.

2. Particle size control: Controlling particle size to ensure uniformity and bioavailability.

 

Quality Control Challenges:

1. Assay: Ensuring accurate assay of Calcium Succinate content.

2. Impurity profiling: Detecting and controlling impurities.

 

Regulatory Challenges:

1. Compliance with GMP: Ensuring compliance with Good Manufacturing Practice (GMP) regulations.

2. Documentation and validation: Maintaining detailed documentation and validating the manufacturing process.

 

Dosage Form-Specific Challenges:

1. Tablets: Ensuring tablet hardness, friability, and dissolution.

2. Capsules: Ensuring uniform filling and capsule integrity.

 

Addressing these challenges ensures the production of high-quality Calcium Succinate dosage forms.

 

·         What is the Packing for Calcium Succinate  Manufactured by MEDIOCON INC?

 

Calcium Succinate packaging typically involves:

 

Containers:

1. Drums: Fiber drums or plastic drums for bulk packaging.

2. Bags: Multi-layer bags or foil bags for smaller quantities.

3. Bottles: Glass or plastic bottles for pharmaceutical-grade Calcium Succinate.

 

Protective Measures:

1. Moisture control: Desiccants or moisture-absorbing materials may be used.

2. Light protection: Light-resistant packaging or containers may be used.

 

Labeling:

1. Product identification: Clear labeling of product name, strength, and quantity.

2. Handling instructions: Instructions for handling, storage, and transportation.

 

Quality Control:

1. Packaging material quality: Ensuring packaging materials meet quality standards.

2. Packaging integrity: Verifying packaging integrity to prevent contamination or damage.

 

Proper packaging helps maintain the quality and stability of Calcium Succinate.

 

·         What is shelf life Of Calcium Succinate  Manufactured by MEDIOCON INC? 

 

The shelf life of Calcium Succinate depends on various factors, including:

 

Storage Conditions:

1. Temperature: Store in a cool, dry place, away from direct sunlight and heat sources.

2. Humidity: Store in a dry environment to prevent moisture absorption.

 

Packaging:

1. Airtight containers: Store in airtight containers to prevent exposure to air and moisture.

 

General Guidelines:

1. Manufacturer's specifications: Follow the manufacturer's recommended shelf life and storage conditions.

2. Regulatory requirements: Comply with regulatory requirements for shelf life and storage.

 

Typical Shelf Life:

1. 2-5 years: The shelf life of Calcium Succinate can range from 2 to 5 years, depending on the storage conditions and packaging.

 

It's essential to check the product label or consult with the manufacturer for specific shelf life information.

 

 

·         What should the label claim for Calcium Succinate  Manufactured by MEDIOCON INC   Include?

 

The label claim for Calcium Succinate should include:

 

Essential Information:

1. Product name: Calcium Succinate

2. Strength: Amount of Calcium Succinate per serving or unit

3. Net weight or quantity: Total amount of product in the container

4. Manufacturer's name and address: Contact information for the manufacturer

5. Directions for use: Instructions for taking or using the product

 

Additional Information:

1. Ingredients: List of ingredients used in the product

2. Allergen warnings: Warnings about potential allergens or sensitivities

3. Storage instructions: Instructions for storing the product to maintain its quality

4. Expiration date or shelf life: Date after which the product may not retain its potency or quality

 

Regulatory Compliance:

1. Compliance with regulations: Ensure the label complies with relevant regulatory requirements, such as those related to food supplements or pharmaceuticals.

 

·         Where can Calcium Succinate  Manufactured by MEDIOCON INC are procured?

Calcium Succinate Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

1.      FOR API

 MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com            

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com            

 GST No: 27DHUPM2366D1ZZ

 

2.      For Dosage Forms :

     - Online Marketplaces: You can find Calcium Succinate Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

 - Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in             

   your area for Calcium Succinate  Manufactured by MEDIOCON INC  products.

 Remember to ensure the quality and authenticity of the Calcium Succinate Manufactured by MEDIOCON INC product, regardless of the procurement source.