Fever Few Extract 89997-65-9 Manufacturer Exporter MEDIOCON INC

 

Fever Few Extract Manufactured by MEDIOCON INC     

 

·   Name: Feverfew extract

 

·      CAS No: 89997-65-9

 

 

·   Molecular Weight: 248.32g/mol

 

·   Molecular formula: C₁₅H₂₀O₃

 

·   Synonyms:  anacetum parthenium extract.

 

                                                        

·   Appearance:  Dark amber colour Liquid. 

 

·   Solubility :  soluble in  ethanol.

                  

·   Use :

                                                                   

Feverfew extract is used for various purposes, including:

 

Health Benefits:

 

1. Migraine prevention: Reducing frequency and severity of migraines.

2. Anti-inflammatory: Relieving pain and inflammation.

3. Antioxidant: Protecting against oxidative stress.

 

Traditional Uses:

 

1. Fever reduction: Historically used to reduce fever.

2. Digestive issues: Relieving digestive discomfort.

 

Other Potential Uses:

 

1. Arthritis: Reducing inflammation and pain.

2. Skin issues: Anti-inflammatory and antioxidant effects.

 

Precautions:

 

1. Pregnancy and breastfeeding: Consult a healthcare professional.

2. Allergies: Potential allergic reactions.

 

Feverfew extract's effectiveness and safety may vary depending on individual circumstances.

 

 

 

 

·      How is Feverfew extract manufactured by MEDIOCON INC Synthesized?

 

Achyranthes aspera extract synthesis involves various methods, including:

 

Extraction Methods:

 

1. Solvent extraction: Using solvents like ethanol, methanol, or water.

2. Cold pressing: Mechanical extraction.

3. Soxhlet extraction: Continuous extraction.

 

Purification Methods:

 

1. Filtration: Removing impurities.

2. Concentration: Evaporating solvents.

3. Chromatography: Separating compounds.

 

Standardization:

 

1. Marker compound identification: Identifying specific compounds.

2. Quantification: Measuring compound concentrations.

 

Quality Control:

 

1. Testing for purity: Ensuring extract quality.

2. Testing for potency: Verifying bioactive compound levels.

 

The synthesis process may vary depending on desired extract properties and intended use.

 

·   What are the different  dosage forms  of   Fever Few Extract Manufactured  by  MEDIOCON INC?

 

Feverfew extract is available in various dosage forms, including:

 

Oral Dosage Forms:

 

1. Capsules: Encapsulated extract for oral consumption.

2. Tablets: Compressed extract in tablet form.

3. Powders: Loose powder for mixing with food or drinks.

 

Other Dosage Forms:

 

1. Teas: Herbal teas made from feverfew leaves or flowers.

2. Tinctures: Liquid extracts for sublingual use.

 

Combination Products:

 

1. Herbal blends: Combinations with other herbs.

2. Supplement formulas: Feverfew extract combined with other supplements.

 

The choice of dosage form depends on individual preferences and needs.

 

·         How Fever Few Extract Manufactured by MEDIOCON INC   Dosage Forms are prepared?

Feverfew extract dosage forms are prepared through:

 

Extraction and Processing:

 

1. Harvesting and drying of feverfew leaves or flowers.

2. Extraction using solvents (e.g., ethanol, water).

3. Filtration and concentration.

 

Dosage Form Preparation:

 

1. Capsules: Filling capsules with standardized extract.

2. Tablets: Compressing granulated extract into tablets.

3. Powders: Packaging powdered extract.

 

Quality Control:

 

1. Standardization of bioactive compounds (e.g., parthenolide).

2. Testing for purity, potency, and contaminants.

 

Manufacturing Considerations:

 

1. Good Manufacturing Practices (GMP).

2. Quality assurance and control.

 

The process ensures high-quality feverfew extract dosage forms.

 

·         What are the appropriate Dosage forms of Fever Few Extract Manufactured  by  MEDIOCON   INC?

Appropriate dosage forms of Feverfew Extract include:

 

Oral Dosage Forms:

 

1. Capsules: Standardized extract in capsule form.

2. Tablets: Compressed tablets containing feverfew extract.

3. Powders: Powdered extract for mixing with food or drinks.

 

Considerations:

 

1. Standardization: Ensuring consistent levels of bioactive compounds (e.g., parthenolide).

2. Dosage: Following recommended dosages for therapeutic benefits.

3. Quality: Choosing products from reputable manufacturers.

 

Individualized Dosage:

 

1. Consult a healthcare professional for personalized dosage recommendations.

 

The appropriate dosage form and dosage may vary depending on individual needs and health status.

 

 

 

 

·         When should Fever Few Extract Manufactured by MEDIOCON INC  be taken?

Feverfew extract can be taken:

 

For Migraine Prevention:

 

1. Regularly: Daily or as directed by a healthcare professional.

2. Long-term: To achieve optimal benefits.

 

For General Health:

 

1. As needed: For occasional use.

2. With food: To minimize potential stomach upset.

 

Consult a Healthcare Professional:

 

1. Before starting: Especially if pregnant, breastfeeding, or taking medications.

2. For personalized guidance: To determine optimal dosage and duration.

 

Timing and dosage may vary depending on individual needs and health status.

 

 

·         What are the effects And Side effects of Fever Few Extract Manufactured by MEDIOCON INC?

Feverfew extract's effects and side effects:

 

Therapeutic Effects:

 

1. Migraine prevention: Reducing frequency and severity.

2. Anti-inflammatory: Relieving pain and inflammation.

3. Antioxidant: Protecting against oxidative stress.

 

Potential Side Effects:

 

1. Gastrointestinal issues: Nausea, vomiting, diarrhea.

2. Allergic reactions: Skin rashes, itching.

3. Interactions: With blood thinners, NSAIDs, and other medications.

4. Pregnancy and breastfeeding: Potential risks; consult a healthcare professional.

 

Rare but Serious Side Effects:

 

1. Bleeding disorders: Increased risk of bleeding.

2. Seizures: Rare reports of seizures.

 

Precautions:

 

1. Consult a healthcare professional before starting feverfew extract.

2. Monitor side effects and adjust dosage or discontinue use if necessary.

 

 

 

 

·         How is Fever Few Extract Manufactured by MEDIOCON  INC  Tested Qualitatively?

Feverfew extract qualitative testing involves:

 

Methods:

 

1. High-Performance Liquid Chromatography (HPLC): Analyzing bioactive compounds like parthenolide.

2. Gas Chromatography (GC): Identifying volatile compounds.

3. Mass Spectrometry (MS): Confirming compound identity.

 

Parameters:

 

1. Parthenolide content: Quantifying the primary bioactive compound.

2. Purity: Detecting contaminants or adulterants.

3. Identity: Verifying feverfew extract authenticity.

 

Testing Objectives:

 

1. Quality control: Ensuring extract quality and consistency.

2. Standardization: Verifying bioactive compound levels.

 

Regulatory Compliance:

 

1. Adherence to standards: Meeting regulatory requirements.

 

Qualitative testing ensures feverfew extract's quality, efficacy, and safety.

 

·         Which tests are performed on Fever Few Extract Manufactured by  MEDIOCON INC ?

Feverfew extract testing typically includes:

 

Physical and Chemical Tests:

 

1. High-Performance Liquid Chromatography (HPLC): Quantifying parthenolide and other bioactive compounds.

2. Gas Chromatography (GC): Analyzing volatile compounds.

3. Mass Spectrometry (MS): Confirming compound identity.

 

Quality Control Tests:

 

1. Purity testing: Detecting contaminants or adulterants.

2. Potency testing: Verifying bioactive compound levels.

3. Identity testing: Confirming feverfew extract authenticity.

 

Microbial Tests:

 

1. Microbial limit testing: Ensuring compliance with microbial standards.

 

Other Tests:

 

1. Heavy metal testing: Detecting heavy metal contaminants.

2. Pesticide residue testing: Ensuring compliance with pesticide regulations.

 

These tests ensure feverfew extract's quality, safety, and efficacy.

 

·         What are the challenges in Manufacturing of Fever Few Extract Manufactured by MEDIOCON   INC API?

The manufacturing of Feverfew Extract API (Active Pharmaceutical Ingredient) faces several challenges, including:

 

Raw Material Challenges:

 

1. Quality variation: Variations in feverfew plant quality, freshness, and sourcing.

2. Supply chain management: Ensuring consistent supply and managing logistics.

 

Extraction Challenges:

 

1. Efficient extraction methods: Optimizing extraction techniques for high-quality API.

2. Yield and purity: Achieving desired API yield and purity levels.

 

Quality Control Challenges:

 

1. Standardization: Ensuring consistent quality and composition.

2. Regulatory compliance: Meeting regulatory requirements and standards.

 

Manufacturing Challenges:

 

1. Scalability: Scaling up production while maintaining quality.

2. Cost optimization: Managing production costs while ensuring quality.

 

Other Challenges:

 

1. Adulteration: Preventing adulteration and ensuring authenticity.

2. Stability and shelf life: Ensuring API stability and shelf life.

 

These challenges require careful planning, quality control, and regulatory compliance to ensure high-quality Feverfew Extract API.

 

·         What are the challenges in manufacturing of Fever Few Extract Manufactured by MEDIOCON  INC ’s Dosage forms?

The manufacturing of Feverfew Extract dosage forms faces several challenges, including:

 

Formulation Challenges:

 

1. Stability and compatibility: Ensuring extract stability and compatibility with excipients.

2. Bioavailability: Optimizing extract bioavailability.

 

Manufacturing Challenges:

 

1. Scalability: Scaling up production while maintaining quality.

2. Process optimization: Optimizing manufacturing processes.

 

Quality Control Challenges:

 

1. Standardization: Ensuring consistent quality and potency.

2. Regulatory compliance: Meeting regulatory requirements.

 

Dosage Form-Specific Challenges:

 

1. Capsules: Uniform filling and content uniformity.

2. Tablets: Compression and disintegration.

 

Other Challenges:

 

1. Raw material variability: Managing extract variability.

2. Cost optimization: Balancing quality and cost.

 

These challenges require careful formulation, manufacturing, and quality control to ensure high-quality Feverfew Extract dosage forms.

 

·         What is the Packing for Fever Few Extract Manufactured by MEDIOCON INC?

Feverfew extract is typically packed in:

 

Containers:

 

1. Airtight containers: Protecting from moisture and air.

2. Glass or plastic bottles: Suitable for capsules or powders.

3. Blister packs: For tablet or capsule forms.

 

Packaging Features:

 

1. Light protection: Protecting from light degradation.

2. Tamper-evident: Ensuring product integrity.

3. Labeling: Clear labeling with product information and instructions.

 

Special Considerations:

 

1. Moisture control: Preventing moisture absorption.

2. Temperature control: Maintaining stable temperatures.

 

The packaging ensures feverfew extract's quality, potency, and safety.

 

 

·         What is shelf life Of Fever Few Extract Manufactured by MEDIOCON INC? 

The shelf life of Feverfew Extract typically ranges from:

 

Unopened:

 

1. 2-3 years: When stored properly in a cool, dry place.

 

Opened:

 

1. 1-2 years: When stored properly in a cool, dry place, tightly sealed.

 

Factors Affecting Shelf Life:

 

1. Storage conditions: Exposure to heat, light, or moisture.

2. Container quality: Airtight, light-resistant containers.

3. Handling practices: Minimizing contamination and exposure.

 

Storage Tips:

 

1. Cool, dry place: Away from direct sunlight and heat sources.

2. Tightly sealed: Minimize exposure to air.

 

Proper storage and handling help maintain feverfew extract's quality and potency.

 

·         What should the label claim for Fever Few Extract Manufactured by MEDIOCON INC   Include?

The label claim for Feverfew Extract should include:

 

Key Information:

 

1. Product name: Feverfew Extract or specific product name.

2. Standardization: Parthenolide content or other bioactive compounds.

3. Dosage instructions: Recommended daily intake.

4. Warning statements: Potential interactions or contraindications.

5. Storage instructions: Cool, dry place, away from light.

6. Expiration date: Shelf life or expiration date.

7. Manufacturer information: Name and contact details.

 

Regulatory Compliance:

 

1. Compliance with regulations: Meeting labeling requirements.

 

Additional Information:

 

1. Allergen warnings: Potential allergens or sensitivities.

2. Vegetarian/Vegan status: Suitable for vegetarian or vegan diets.

 

The label claim should provide clear, accurate information to ensure safe and effective use.

 

·         Where can Fever Few Extract Manufactured by MEDIOCON INC are procured?

Fever Few Extract Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

1.      FOR API

 MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com            

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com            

 GST No: 27DHUPM2366D1ZZ

 

2.      For Dosage Forms :

     - Online Marketplaces: You can find Fever Few Extract Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

 - Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in             

   your area for Fever Few Extract Manufactured by MEDIOCON INC  products.

 Remember to ensure the quality and authenticity of the Fever Few Extract Manufactured by MEDIOCON INC product, regardless of the procurement source.