Sodium Ascorbate 134-03-2 Manufacturer Exporter MEDIOCON INC

 

Sodium Ascorbate  Manufactured by MEDIOCON INC     

 

·   Name: Sodium Ascorbate

 

·      CAS No: 134-03-2

 

 

·   Molecular Weight: 198.11 g/mol

 

·   Molecular formula: C₆H₇NaO₆

 

·   Synonyms: Vitamin C sodium salt

 

                                                        

·   Appearance:  white to off white crystalline powder. 

 

·   Solubility :  Highly soluble in water.

                  

·   Use :

                                                                   

Sodium Ascorbate is a form of Vitamin C:

 

Uses:

1. Antioxidant: Protects against oxidative stress.

2. Immune system support: Boosts immune function.

3. Collagen production: Supports skin and connective tissue health.

4. Iron absorption: Enhances iron absorption.

 

Applications:

1. Dietary supplements: Used in vitamin C supplements.

2. Food industry: Added to foods and beverages as a preservative.

3. Pharmaceuticals: Used in medications for various health conditions.

 

Benefits:

1. Antioxidant properties: Protects against cell damage.

2. Immune system support: Helps fight off infections.

3. Skin health: Supports collagen production and skin health.

 

Sodium Ascorbate is a versatile compound with various applications.

 

·      How is Sodium Ascorbate  extract manufactured by MEDIOCON INC Synthesized?

 

Sodium Ascorbate can be synthesized through various methods:

 

Synthesis Methods:

1. Fermentation: Microbial fermentation of glucose or other sugars.

2. Chemical synthesis: Reichstein process or other chemical reactions.

3. Enzymatic synthesis: Enzyme-catalyzed reactions.

 

Production Steps:

1. Raw material selection: Choosing suitable raw materials (e.g., glucose).

2. Fermentation or reaction: Converting raw materials into ascorbic acid.

3. Purification: Purifying the resulting ascorbic acid.

4. Sodium ascorbate formation: Reacting ascorbic acid with sodium hydroxide.

 

Quality Control:

1. Purity testing: Ensuring the purity of sodium ascorbate.

2. Quality assurance: Verifying the product meets standards.

 

The synthesis method may vary depending on the manufacturer and intended application.

 

 

·   What are the different  dosage forms  of   Sodium Ascorbate  Manufactured  by  MEDIOCON INC?

 

Sodium Ascorbate can be formulated into various dosage forms:

 

Dosage Forms:

1. Tablets

2. Capsules

3. Powder

4. Injectable solutions

5. Effervescent tablets

6. Topical creams or serums

 

These dosage forms cater to different needs, such as oral supplementation, injectable administration, or topical application.

 

·         How Sodium Ascorbate  Manufactured by MEDIOCON INC   Dosage Forms are prepared?

 

Sodium Ascorbate dosage forms are prepared through various processes:

 

Preparation of Oral Dosage Forms:

1. Tablets: Mixing sodium ascorbate with excipients, granulation, and compression.

2. Capsules: Filling capsules with sodium ascorbate powder or granules.

3. Powder: Mixing sodium ascorbate with other ingredients and packaging.

 

Preparation of Parenteral Dosage Forms:

1. Injectable solutions: Dissolving sodium ascorbate in water for injection, sterilization, and packaging.

 

Preparation of Topical Dosage Forms:

1. Creams or serums: Mixing sodium ascorbate with other ingredients, homogenization, and packaging.

 

Quality Control:

1. Assay: Verifying the amount of sodium ascorbate in the dosage form.

2. Purity: Ensuring the absence of impurities.

3. Stability: Evaluating the stability of the dosage form.

 

The preparation process may vary depending on the dosage form and manufacturer.

 

·         What are the appropriate Dosage forms of Sodium Ascorbate  Manufactured  by  MEDIOCON   INC?

The appropriate dosage forms of Sodium Ascorbate depend on the intended use and patient needs:

 

For Oral Supplementation:

1. Tablets: Suitable for high-dose supplementation.

2. Capsules: Convenient for individuals who have difficulty swallowing tablets.

3. Powder: Can be added to food or drinks for easy consumption.

 

For Parenteral Administration:

1. Injectable solutions: Suitable for patients requiring high doses or rapid absorption.

 

For Topical Application:

1. Creams or serums: Can be used for skin health and antioxidant benefits.

 

The choice of dosage form should be based on individual patient needs and medical guidance.

 

·         When should Sodium Ascorbate  Manufactured by MEDIOCON INC  be taken?

 

Sodium Ascorbate can be taken:

 

Timing Options:

1. With meals: To minimize gastrointestinal upset.

2. Between meals: For optimal absorption.

3. As directed: Follow the recommended dosage and timing instructions from a healthcare provider or product label.

Considerations:

1. Individual needs: Consult a healthcare provider for personalized advice.

2. Dosage: Follow the recommended dosage to avoid adverse effects.

It's essential to consult a healthcare provider for specific guidance on taking Sodium Ascorbate.

 

·         What are the effects And Side effects of Sodium Ascorbate  Manufactured by MEDIOCON INC?

Sodium Ascorbate can have various effects and side effects:

 

Effects:

1. Antioxidant properties: Protects against oxidative stress.

2. Immune system support: Boosts immune function.

3. Collagen production: Supports skin and connective tissue health.

 

Side Effects:

1. Gastrointestinal upset: Nausea, diarrhea, or stomach cramps.

2. Kidney stone risk: High doses may increase the risk of kidney stones.

3. Allergic reactions: Rarely, some individuals may experience allergic reactions.

 

Interactions:

1. Medications: Sodium ascorbate may interact with certain medications, such as blood thinners.

 

Precautions:

1. High doses: Consult a healthcare provider before taking high doses.

2. Individuals with kidney disease: May need to limit sodium intake.

 

            It's essential to consult a healthcare provider for personalized advice on taking Sodium Ascorbate.

 

·         How is Sodium Ascorbate  Manufactured by MEDIOCON  INC  Tested Qualitatively?

Sodium Ascorbate can be tested qualitatively using various methods:

 

Qualitative Tests:

1. Titration: Using a titrant to detect the presence of ascorbate.

2. Colorimetric tests: Observing color changes in response to ascorbate.

3. Chromatography: Separating and detecting ascorbate using chromatography techniques.

 

Specific Tests:

1. 2,6-Dichlorophenolindophenol (DCPIP) test: A colorimetric test for ascorbate.

2. Ferric reducing antioxidant power (FRAP) assay: Measures the reducing power of ascorbate.

 

Instrumentation:

1. Spectrophotometry: Measures absorbance or fluorescence.

2. High-performance liquid chromatography (HPLC): Separates and detects ascorbate.

 

These tests help identify and quantify Sodium Ascorbate in various samples.

 

 

·         Which tests are performed on Sodium Ascorbate  Manufactured by  MEDIOCON INC ?

Sodium Ascorbate can undergo various tests:

 

Quality Control Tests:

1. Assay: Verifies the amount of sodium ascorbate.

2. Purity: Checks for impurities and contaminants.

3. pH: Measures the pH of the solution or powder.

 

Analytical Tests:

1. High-performance liquid chromatography (HPLC): Separates and detects sodium ascorbate.

2. Spectrophotometry: Measures absorbance or fluorescence.

3. Titration: Determines the amount of sodium ascorbate.

 

Stability Tests:

1. Accelerated stability testing: Evaluates stability under stress conditions.

2. Long-term stability testing: Assesses stability over time.

 

These tests ensure the quality, purity, and stability of Sodium Ascorbate.

 

·         What are the challenges in Manufacturing of Sodium Ascorbate  Manufactured by MEDIOCON   INC API?

The manufacturing of Sodium Ascorbate API can pose several challenges:

 

Chemical Challenges:

1. Oxidation: Sodium ascorbate is sensitive to oxidation, which can affect its stability and quality.

2. pH control: Maintaining the optimal pH range is crucial to ensure the stability and quality of sodium ascorbate.

 

Process Challenges:

1. Process optimization: Optimizing the manufacturing process to ensure consistency and quality.

2. Scalability: Scaling up the manufacturing process while maintaining quality and consistency.

 

Quality Control Challenges:

1. Purity testing: Ensuring the purity of sodium ascorbate API.

2. Stability testing: Evaluating the stability of sodium ascorbate API under various conditions.

 

Regulatory Challenges:

1. Compliance with GMP: Ensuring compliance with Good Manufacturing Practice regulations.

2. Documentation and validation: Maintaining detailed documentation and validating the manufacturing process.

 

Addressing these challenges is essential to ensure the production of high-quality Sodium Ascorbate API.

 

·         What are the challenges in manufacturing of Sodium Ascorbate  Manufactured by MEDIOCON  INC ’s Dosage forms?

The manufacturing of Sodium Ascorbate dosage forms can pose several challenges:

 

Formulation Challenges:

1. Stability: Ensuring the stability of sodium ascorbate in the dosage form.

2. Excipient compatibility: Selecting excipients that are compatible with sodium ascorbate.

 

Manufacturing Challenges:

1. Process optimization: Optimizing the manufacturing process to ensure consistency and quality.

2. Scale-up: Scaling up the manufacturing process while maintaining quality and consistency.

 

Quality Control Challenges:

1. Content uniformity: Ensuring uniform distribution of sodium ascorbate in the dosage form.

2. Stability testing: Evaluating the stability of the dosage form under various conditions.

 

Regulatory Challenges:

1. Compliance with GMP: Ensuring compliance with Good Manufacturing Practice regulations.

2. Validation and documentation: Maintaining detailed documentation and validating the manufacturing process.

 

Addressing these challenges is essential to ensure the production of high-quality Sodium Ascorbate dosage forms.

 

 

·         What is the Packing for Sodium Ascorbate  Manufactured by MEDIOCON INC?

The packaging for Sodium Ascorbate may vary depending on the dosage form and intended use:

 

Packaging Options:

1. Airtight containers: Protects against moisture and oxidation.

2. Light-resistant containers: Protects against degradation caused by light.

3. Moisture-control packaging: Maintains a stable environment to prevent degradation.

 

Specific Packaging:

1. Bottles: Glass or plastic bottles with tight-fitting lids.

2. Sachets: Individual packets containing a single dose.

3. Blister packs: Unit-dose packaging for tablets or capsules.

 

The packaging should ensure the stability, quality, and safety of Sodium Ascorbate during storage and transportation.

 

·         What is shelf life Of Sodium Ascorbate  Manufactured by MEDIOCON INC? 

 

Sodium Ascorbate's shelf life varies depending on storage conditions and packaging. Here are some general guidelines:

 

- Typical Shelf Life: 60 months (5 years) when stored properly, according to Loba Chemie.

- Storage Conditions: Store in a well-closed, non-metallic container, protected from light, in a cool, dry place.

- Stability: Sodium ascorbate is relatively stable in air but gradually darkens on exposure to light. Aqueous solutions are unstable and subject to rapid oxidation in air at pH > 6.0.

- Factors Affecting Shelf Life: Temperature, moisture, oxygen, light, pH, and presence of metal ions can impact the stability of sodium ascorbate.¹

 

To maintain its potency and extend shelf life, consider the following:

- Minimize Exposure: Limit exposure to air, light, and moisture.

- Proper Packaging: Use airtight, light-resistant containers.

- Controlled Environment: Store in a cool, dry place with stable temperature and humidity levels.

 

Keep in mind that the actual shelf life may vary depending on specific product formulations and storage conditions. Always check the product label or consult with the manufacturer for specific guidance.

 

·         What should the label claim for Sodium Ascorbate  Manufactured by MEDIOCON INC   Include?

The label claim for Sodium Ascorbate should include:

 

Essential Information:

1. Product name: Sodium Ascorbate.

2. Dosage form: Specify the dosage form (e.g., tablets, capsules, powder).

3. Strength: Amount of sodium ascorbate per dosage unit (e.g., mg per tablet).

4. Net weight or volume: Quantity of product in the container.

5. Directions for use: Instructions for taking or using the product.

6. Storage conditions: Recommendations for storing the product (e.g., cool, dry place).

7. Expiration date: Date after which the product should not be used.

 

Additional Information:

1. Ingredients: List of ingredients, including any allergens or sensitizers.

2. Warning or caution statements: Any relevant warnings or cautions for use.

3. Manufacturer's information: Name and contact information of the manufacturer.

 

The label claim should comply with regulatory requirements and provide clear, accurate information to users.

 

·         Where can Sodium Ascorbate  Manufactured by MEDIOCON INC are procured?

Sodium Ascorbate Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

1.      FOR API

 MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com           

 GST No: 27DHUPM2366D1ZZ

 

2.      For Dosage Forms :

     - Online Marketplaces: You can find Sodium Ascorbate Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

 - Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in             

   your area for Sodium Ascorbate  Manufactured by MEDIOCON INC  products.

 Remember to ensure the quality and authenticity of the Sodium Ascorbate Manufactured by MEDIOCON INC product, regardless of the procurement source.