Sodium Propionate 137-40-6 Manufacturer Exporter MEDIOCON INC

 

Sodium Propionate Manufactured by MEDIOCON INC     

 

·   Name: Sodium Propionate

 

·   CAS No : 137-40-6

 

·   Molecular Weight: 96.07g/mol

 

 

·   Molecular formula:  C₃H₅O₂Na

 

 

·   Synonyms :    Sodium propanoate

 

 

·   Appearance :    white, crystalline powder or granules.

 

·   Solubility:  soluble in water, forming alkaline solutions. It is slightly soluble in       

 

                       alcohol

 

·   Use :

 

Sodium propionate is a food preservative commonly used to:

 

Applications

1. Prevent mold and yeast growth: Extending shelf life in baked goods, dairy products, and processed meats.

2. Inhibit microbial growth: Preserving freshness and safety in various food products.

 

Benefits

1. Effective preservative: Sodium propionate is effective against a wide range of microorganisms.

2. Wide usage: Used in various industries, including food, pharmaceuticals, and cosmetics.

 

Precautions

1. Allergic reactions: Some individuals may experience allergic reactions or sensitivities.

2. Regulatory compliance: Ensure compliance with regulatory requirements and guidelines.

 

Sodium propionate is generally recognized as safe (GRAS) by regulatory agencies when used within specified limits.

How is  Sodium Propionate  manufactured by MEDIOCON INC Synthesized?

 

Sodium propionate is synthesized through a chemical reaction between propionic acid and sodium carbonate or sodium hydroxide. The reaction produces sodium propionate, which is then isolated in crystalline form.

 

Synthesis Process:

 

- Reaction: Propionic acid reacts with sodium carbonate or sodium hydroxide to form sodium propionate.

- Crystallization: The resulting solution is cooled and treated to isolate pure sodium propionate in crystalline form.

- Purification: The crystalline sodium propionate may undergo further purification steps to meet desired quality standards.

 

Chemical Reaction:

 

CH₃CH₂COOH (propionic acid) + NaOH (sodium hydroxide) → CH₃CH₂COONa (sodium propionate) + H₂O¹

 

Sodium propionate can be produced in various forms, including anhydrous and hydrated forms, with different applications in industries such as food, pharmaceuticals, and cosmetics.

 

 

·         What are the different dosage forms of Sodium Propionate  Manufactured by MEDIOCON INC?

 

Sodium propionate is available in various dosage forms, including:

Dosage Forms

1. Powder: Used as a food preservative or in pharmaceutical applications.

2. Granules: May be used in food or pharmaceutical applications.

3. Solutions: Liquid solutions for use in food, pharmaceutical, or cosmetic applications.

4. Tablets or capsules: May be used in pharmaceutical applications.

 

Applications

1. Food industry: As a preservative in baked goods, dairy products, and processed meats.

2. Pharmaceutical industry: As an excipient or preservative in various pharmaceutical products.

3. Cosmetic industry: As a preservative in cosmetic products.

The specific dosage form and application may vary depending on the intended use and regulatory requirements.

 

·         How Sodium Propionate  Manufactured by MEDIOCON INC   Dosage Forms are prepared?

 

Sodium propionate dosage forms are prepared through various methods, depending on the intended use and dosage form. Here are some general preparation methods:

 

Powder Preparation

1. Synthesis: Sodium propionate is synthesized through a chemical reaction.

2. Crystallization: The resulting solution is cooled and treated to isolate pure sodium propionate in crystalline form.

3. Milling: The crystalline sodium propionate is milled into a fine powder.

Solution Preparation

1. Dissolution: Sodium propionate powder is dissolved in a suitable solvent, such as water.

2. Filtration: The solution may be filtered to remove impurities.

3. Sterilization: The solution may be sterilized through methods like autoclaving or filtration.

 

Tablet or Capsule Preparation

1. Blending: Sodium propionate powder is blended with other excipients.

2. Granulation: The blend may undergo granulation to improve flow and compression properties.

3. Tableting or encapsulation: The granules are compressed into tablets or filled into capsules.

 

The preparation method may vary depending on the specific application, regulatory requirements, and desired product characteristics.

 

 

·         What are the appropriate Dosage forms of Sodium Propionate  Manufactured  by  MEDIOCON   INC?

 

The appropriate dosage forms of sodium propionate depend on its intended use:

 

Food Industry

1. Powder: Added directly to food products as a preservative.

2. Solution: Used as a preservative in liquid food products.

 

Pharmaceutical Industry

1. Topical creams or ointments: Used to treat fungal infections or as a preservative.

2. Oral tablets or capsules: May be used as an antifungal agent or preservative.

 

Cosmetic Industry

1. Creams or lotions: Used as a preservative to prevent microbial growth.

2. Shampoos or conditioners: May be used as a preservative.

 

The choice of dosage form depends on the specific application, desired release characteristics, and regulatory requirements.

 

·         When should Sodium Propionate  Manufactured by MEDIOCON INC be taken?

 

Sodium propionate is typically used as a food preservative or in pharmaceutical/cosmetic applications, rather than being taken as a medication. However, if used as a medication, the timing would depend on the specific product and condition being treated.

 

General Guidance

1. Follow product instructions: Use sodium propionate products according to the manufacturer's instructions.

2. Consult a healthcare professional: If using sodium propionate for medical purposes, consult a healthcare professional for guidance on usage and timing.

 

Food Preservative

1. Added to food products: Sodium propionate is typically added to food products during processing to extend shelf life.

The specific usage and timing may vary depending on the product and application. Always follow the recommended usage guidelines.

 

·         What are the effects And Side effects of Sodium Propionate  Manufactured by MEDIOCON INC?

 

Sodium propionate is generally recognized as safe (GRAS) by regulatory agencies, but like any substance, it can have effects and potential side effects:

 

Effects

1. Antimicrobial properties: Effective against mold, yeast, and some bacteria.

2. Preservative properties: Extends shelf life of food and pharmaceutical products.

 

Potential Side Effects

1. Allergic reactions: Rarely, some individuals may experience allergic reactions, such as skin irritation or respiratory issues.

2. Gastrointestinal issues: High doses may cause gastrointestinal upset, such as nausea or diarrhea.

 

Precautions

1. Sensitive individuals: Some people may be more sensitive to sodium propionate, and experience adverse effects at lower doses.

2. Regulatory compliance: Ensure compliance with regulatory requirements and guidelines for use.

 

Overall, sodium propionate is considered safe when used within recommended limits and guidelines.

 

 

·         How is Sodium Propionate  Manufactured by MEDIOCON INC Tested Qualitatively?

 

Sodium propionate is tested qualitatively through various analytical techniques, including:

 

*Chemical Testing*

1. *Titration*: Quantitative determination of sodium propionate content.

2. *Spectroscopy*: Infrared (IR) or nuclear magnetic resonance (NMR) spectroscopy for identification and characterization.

3. *Chromatography*: High-performance liquid chromatography (HPLC) or gas chromatography (GC) for separation and detection.

 

*Physical Testing*

1. *Appearance and solubility*: Evaluation of physical characteristics, such as appearance, solubility, and melting point.

*Quality Control*

1. *Purity testing*: Evaluation of impurities and contaminants.

2. *Content uniformity*: Ensuring consistent levels of sodium propionate in products.

These tests ensure the quality, purity, and identity of sodium propionate.

 

·         Which tests are performed on Sodium Propionate  Manufactured by MEDIOCON INC?

Various tests are performed on sodium propionate to ensure its quality and purity. These tests include:

 

Chemical Tests

1. Assay: Quantitative determination of sodium propionate content.

2. Identification tests: Infrared (IR) spectroscopy or other methods to confirm identity.

 

Physical Tests

1. Appearance: Evaluation of color, odor, and texture.

2. Solubility: Determination of solubility in water or other solvents.

 

Purity Tests

1. Impurity testing: Evaluation of impurities, such as heavy metals or other contaminants.

2. Moisture content: Determination of water content.

 

Microbial Tests

1. Microbial limit testing: Evaluation of microbial contamination, such as bacteria, yeast, or mold.

These tests ensure the quality, purity, and safety of sodium propionate for use in food, pharmaceutical, or cosmetic applications.

 

·         What are the challenges in Manufacturing of Sodium Propionate  Manufactured by MEDIOCON   INC API?

 

The challenges in manufacturing Sodium Propionate API (Active Pharmaceutical Ingredient) include:

 

Raw Material Challenges

1. Quality and sourcing: Ensuring high-quality raw materials, such as propionic acid.

2. Supply chain reliability: Securing reliable sources of raw materials.

 

Synthesis Challenges

1. Reaction conditions: Optimizing reaction conditions to achieve high yields and purity.

2. Impurity control: Minimizing impurities and ensuring consistent quality.

 

Purification Challenges

1. Crystallization: Optimizing crystallization conditions to achieve desired particle size and purity.

2. Drying and handling: Ensuring proper drying and handling to prevent degradation or contamination.

 

Regulatory Challenges

1. Compliance with GMP: Adhering to Good Manufacturing Practices (GMP) regulations.

2. Regulatory approvals: Obtaining necessary approvals and certifications.

 

Quality Control Challenges

1. Analytical method development: Developing and validating analytical methods for quality control.

2. Batch-to-batch consistency: Ensuring consistent quality across batches.

 

Addressing these challenges is crucial to ensure the quality, safety, and efficacy of Sodium Propionate API.

 

 

What are the challenges in manufacturing of Sodium Propionate  Manufactured by MEDIOCON  INC ’s Dosage forms?

 

The challenges in manufacturing Sodium Propionate dosage forms include:

Formulation Challenges

1. Compatibility issues: Ensuring compatibility with other excipients and active ingredients.

2. Stability and degradation: Preventing degradation or instability of Sodium Propionate.

Manufacturing Challenges

1. Uniformity and blending: Achieving uniform blending and distribution of Sodium Propionate.

2. Particle size control: Controlling particle size to ensure consistent release characteristics.

Quality Control Challenges

1. Assay and content uniformity: Ensuring accurate assay and content uniformity.

2. Impurity profiling: Detecting and controlling impurities.

 

Regulatory Challenges

1. Compliance with GMP: Adhering to Good Manufacturing Practices (GMP) regulations.

2. Regulatory submissions: Preparing and submitting regulatory documents.

 

Scale-up Challenges

1. Process optimization: Scaling up manufacturing processes while maintaining quality.

2. Equipment and technology: Selecting suitable equipment and technology.

Addressing these challenges ensures the quality, safety, and efficacy of Sodium Propionate dosage forms.

 

 

 

·         What is the Packing for Sodium Propionate  Manufactured by MEDIOCON INC?

 

Sodium propionate is typically packaged in various forms, including:

 

Packaging Options

1. Drums: Fiber drums or plastic drums with liners.

2. Bags: Multi-wall paper bags or plastic bags.

3. Containers: Airtight containers, such as plastic or stainless steel containers.

 

Packaging Considerations

1. Moisture protection: Protecting sodium propionate from moisture to prevent caking or degradation.

2. Air-tight packaging: Ensuring packaging is airtight to prevent contamination and exposure to air.

3. Labeling and documentation: Proper labeling and documentation, including safety data sheets (SDS).

 

The specific packaging used may vary depending on the intended use, quantity, and regulatory requirements.

 

·         What is shelf life Of Sodium Propionate  Manufactured by MEDIOCON INC? 

 

The shelf life of Sodium Propionate typically depends on various factors, including:

 

Storage Conditions

1. Temperature: Store in a cool, dry place, away from direct sunlight and heat sources.

2. Humidity: Keep away from moisture to prevent caking or degradation.

 

Packaging

1. Airtight containers: Store in airtight containers to prevent contamination and exposure to air.

 

General Guidelines

1. Typical shelf life: 2-5 years, depending on the manufacturer and storage conditions.

2. Check manufacturer's guidelines: Verify the shelf life with the manufacturer or supplier, as it may vary.

 

Proper storage and handling can help maintain the quality and effectiveness of Sodium Propionate throughout its shelf life.

·         What should the label claim for Sodium Propionate  Manufactured by MEDIOCON INC Include?

 

The label claim for Sodium Propionate should include:

 

Essential Information

1. Product name: Sodium Propionate.

2. Concentration: Specify the concentration or percentage of Sodium Propionate.

3. Net weight: Indicate the net weight or quantity of the product.

4. Manufacturer's information: Include the manufacturer's name, address, and contact details.

Safety Information

1. Hazard warnings: Include hazard warnings or cautionary statements, if applicable.

2. Handling instructions: Provide handling instructions to ensure safe use.

Regulatory Compliance

1. Regulatory compliance: Comply with relevant regulatory requirements, such as labeling regulations.

2. Batch number: Include the batch number and expiration date.

Usage Information

1. Usage instructions: Provide usage instructions or guidelines for use.

2. Storage conditions: Specify storage conditions to maintain product quality.

The label claim should be accurate, clear, and compliant with relevant regulations.

 

Where can Sodium Propionate Manufactured by MEDIOCON INC are procured?

Sodium Propionate Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

1.      FOR API

 MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com           

 GST No: 27DHUPM2366D1ZZ

 

 

2.      For Dosage Forms :

     - Online Marketplaces: You can find Sodium Propionate Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

 - Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in your area for Sodium Propionate Manufactured by MEDIOCON INC products.

 Remember to ensure the quality and authenticity of the Sodium Propionate Manufactured by MEDIOCON INC product, regardless of the procurement source.