Aurantium Extract Manufacturer Exporter MEDIOCON INC

 

 

Aurantium Extract Manufactured by MEDIOCON INC     

 

   Name: Aurantium Extract

 

   CAS No: NA

 

Molecular Weight:  NA

 

  Molecular formula:  NA

 

Synonyms:  Bitter Orange Extract

 

Appearance:  A yellow to brown powder.

 

   Solubility:    water-insoluble, water, ethanol, and methanol are common solvents.

 

    Use :

Aurantium extract, also known as bitter orange extract, has several uses:

 

Weight loss supplements: It's often used to boost metabolism and suppress appetite.

Digestive issues: It may help with indigestion, bloating, and nausea.

Skincare: Antioxidant properties can help with skin issues like acne and aging.

Perfumery: Used in fragrances due to its citrus scent.

Food flavoring: Adds a bitter orange flavor to foods and beverages.

      How is Aurantium Extract manufactured by MEDIOCON INC Synthesized?

Aurantium extract, derived from bitter orange, can be synthesized or extracted through various  

methods, including:

 

Solvent extraction: Using solvents like ethanol or hexane to extract desired compounds.

Cold pressing: Mechanical pressing of peel to obtain essential oils.

Hydro distillation: Steam distillation to extract volatile compounds.

 

The choice of method depends on the desired compounds and product application.

What are the different  dosage forms  of   Aurantium Extract Manufactured  by  MEDIOCON INC?

Aurantium extract is available in various dosage forms, including:

 

Capsules: Oral supplements containing standardized extracts.

Tablets: Similar to capsules, often combined with other ingredients.

Powders: Can be mixed with water or other beverages.

Liquid extracts: Tinctures or solutions for oral use.

Topical creams or gels: For skincare applications.

 

These dosage forms cater to different needs, such as weight loss, digestion, or skin health.

  How Aurantium Extract Manufactured by MEDIOCON INC   Dosage Forms are prepared?

Aurantium extract dosage forms are prepared through various processes, depending on the desired form:

 

1. Capsules/Tablets: Extract is mixed with excipients, filled into capsules or compressed into tablets.

2. Powders: Extract is blended with other ingredients, then filled into packets or containers.

3. Liquid extracts: Extract is dissolved in a solvent, filtered, and bottled.

4. Topical creams/gels: Extract is mixed with creams or gels, ensuring stability and bioavailability.

 

Preparation involves:

 

1. Extraction and purification

2. Standardization

3. Formulation

4. Quality control

5. Packaging

 

What are the appropriate Dosage forms of Aurantium Extract Manufactured  by  MEDIOCON   INC?                

Appropriate dosage forms of Aurantium extract vary depending on the intended use:

1. Weight loss: Capsules or tablets (500-1000 mg, standardized extract)

2. Digestive issues: Capsules or liquid extracts (200-500 mg, 2-3 times a day)

3. Skincare: Topical creams or gels (1-5% extract concentration)

Dosage and form may vary based on individual needs, product formulation, and manufacturer recommendations.

When should Aurantium Extract Manufactured by MEDIOCON INC be taken?

The timing of taking Aurantium extract depends on its intended use:

1. Weight loss: Typically taken before meals (30 minutes to 1 hour) to enhance metabolism and appetite suppression.

2. Digestive issues: Often taken with meals or after meals to aid digestion.

3. Skincare: Topical application as needed, usually morning and night.

It's essential to follow the product's instructions or consult with a healthcare professional for personalized guidance.

    What are the effects And Side effects of Aurantium Extract Manufactured by MEDIOCON INC?

Aurantium extract, also known as bitter orange extract, has various effects and potential side effects.

 

Benefits:

 

- Weight Loss: Aurantium extract may aid in weight loss by increasing metabolic rate, suppressing appetite, and enhancing fat breakdown.

- Improved Sports Performance: It may improve exercise performance by increasing anaerobic power production and endurance.

- Antioxidant and Anti-Inflammatory Properties: Aurantium extract contains flavonoids like hesperidin and naringin, which can help reduce oxidative stress and inflammation.

- Digestive Health: It may help with indigestion, bloating, and nausea.

 

Side Effects:

 

- Cardiovascular Issues: High doses may cause increased heart rate, blood pressure, and risk of cardiovascular events like heart attack, stroke, or arrhythmias.

- Neurological Effects: Anxiety, jitteriness, insomnia, and headaches, including migraines and cluster headaches.

- Gastrointestinal Issues: Nausea, vomiting, abdominal pain, and intestinal colic.

- Sun Sensitivity: Increased risk of sunburn and skin reactions.

 

Precautions:

 

- Interactions with Medications: Aurantium extract may interact with various medications, including MAOIs, stimulants, and certain drugs broken down by the liver.

- Pregnancy and Breastfeeding: Not recommended due to potential risks.

- Surgery: Stop taking Aurantium extract at least 2 weeks before scheduled surgery.

- Certain Health Conditions: Individuals with glaucoma, heart disease, high blood pressure, or irregular heartbeat should exercise caution or avoid using Aurantium extract

  How is Aurantium Extract Manufactured by MEDIOCON  INC  Tested Qualitatively?

Aurantium Extract is tested qualitatively through:

 

High-Performance Liquid Chromatography (HPLC): Identifies and quantifies steviol glycosides.

Gas Chromatography (GC): Analyzes the extract's composition.

Mass Spectrometry (MS): Confirms the presence of specific compounds.

Spectroscopy: Techniques like infrared (IR) spectroscopy help identify functional groups.

 

These tests ensure the quality, purity, and authenticity of Stevia extract.

 

   Which tests are performed on Aurantium Extract Manufactured by  MEDIOCON INC ?

Aurantium extract, like other herbal supplements, undergoes various tests to ensure quality, safety, and efficacy. Some common tests include:

 

1. Chemical analysis: HPLC (High-Performance Liquid Chromatography) or GC (Gas Chromatography) to identify and quantify active compounds like synephrine, flavonoids, and other bioactive molecules.

2. Microbial testing: To ensure the extract is free from harmful microorganisms like bacteria, yeast, and mold.

3. Heavy metal testing: To detect presence of heavy metals like lead, mercury, and arsenic.

4. Pesticide residue testing: To ensure the extract is free from pesticide residues.

5. Standardization: To ensure consistent levels of active compounds.

6. Stability testing: To assess shelf life and storage conditions.

 

These tests help ensure the quality and safety of Aurantium extract products.

What are the challenges in Manufacturing of Stevia Extract Manufactured by MEDIOCON   INC API?

Manufacturing Stevia Extract API poses several challenges, including¹ ² ³:

- Technological Challenges:

    - High-end extraction techniques: Methods like supercritical fluid extraction require significant investment in equipment and expertise, limiting widespread adoption due to cost and technical know-how constraints.

    - Efficient extraction methods: Developing cost-effective and efficient extraction methods that can produce high-quality stevia extracts while minimizing costs is crucial.

- Quality Control and Assurance:

    - Impurities removal: Stevia extract contains a mixture of multiple glycosides and impurities, requiring further isolation and purification to achieve high-purity products.

    - Standardization: Ensuring consistent quality and standardization of stevia extracts is essential for food and beverage applications.

- Raw Material and Supply Chain:

    - Stevia cultivation: Stevia plant cultivation requires specific climatic conditions, and factors like soil quality, temperature, and moisture levels can impact the yield and quality of stevia leaves.

    - Supply chain management: Managing the supply chain for stevia leaves and extracts can be complex, particularly in regions with varying agricultural practices and regulations.

- Regulatory and Compliance:

    - Regulatory approvals: Obtaining regulatory approvals and certifications for stevia extract products can be time-consuming and costly.

    - Compliance with food safety standards: Ensuring compliance with food safety standards and regulations is critical for stevia extract manufacturers.

- Cost and Investment:

    - High capital investment: Setting up a stevia extract manufacturing facility requires significant capital investment in equipment, technology, and infrastructure.

    - Operating costs: Managing operating costs, including labor, utilities, and raw materials, is essential for maintaining profitability in the stevia extract industry.

What are the challenges in manufacturing of Aurantium Extract Manufactured by MEDIOCON  INC ’s Dosage forms?

Manufacturing Aurantium extract dosage forms poses several challenges, including¹ ² ³:

- Stability Issues: Liquid dosage forms are susceptible to chemical and physical changes over time, leading to degradation, alteration of drug potency, and contamination.

- Microbial Contamination: Non-sterile pharmaceutical dosage forms, especially liquid and semisolid forms, pose a risk of microbial contamination, which can impact product quality and safety.

- Product Uniformity: Ensuring consistent potency and appearance of the final product can be challenging, particularly with liquid or semisolid dosage forms.

- Compatibility Issues: Interactions between active ingredients, excipients, and container materials can affect product stability, efficacy, and safety.

- Formulation Challenges: Poor solubility of active ingredients, particle aggregation, and improper mixing or homogenization can lead to inconsistent dosing and product recalls.

- Regulatory Compliance: Manufacturers must adhere to strict guidelines and regulations to ensure product quality, safety, and efficacy.

- Manufacturing Process Failures: Deficiencies in the manufacturing process, such as inadequate quality control measures or equipment failures, can result in defective or unsafe products.

- Container Closure Integrity: Inadequate closure systems can allow entry of oxygen or moisture, leading to product degradation or contamination.

 

These challenges highlight the importance of careful formulation, manufacturing, and quality control processes to ensure the quality and safety of Aurantium extract dosage forms.

What is the Packing for Aurantium Extract Manufactured by MEDIOCON INC?

Aurantium extract packing varies depending on the product and manufacturer. Here are some common packaging options:

- Tablets: 180-tablet packs, often labeled as "Pure Natural and Organic"

- Powder: Various pack sizes, such as¹:

    - 100g: Shri Cirtus Aurantium Extract Powder

    - 200g: Vedik Herbal Aurantium Seed Extract Powder or Shri Citrus Aurantium - Orange Peels Extract Powder

    - 300g: Vedik Herbal Aurantium Seed Extract Powder.

 

 What is shelf life Of Aurantium Extract Manufactured by MEDIOCON INC? 

The shelf life of Aurantium extract varies depending on the product and storage conditions. Here are some general guidelines:

- Citrus Bioflavonoid Extract Powder: 24 months from the manufacturing date when stored in a cool, dry, and dark place.

- Citrus Bioflavonoids Extract 60% Powder: 36 months from the date of manufacture when stored under normal warehouse conditions, off the floor and away from outer walls.

To maintain the quality and extend the shelf life of Aurantium extract, it's essential to:

- Store it in airtight containers

- Keep it away from direct sunlight and moisture

- Follow proper handling and storage instructions

Some studies have also explored the potential of Aurantium extract in prolonging the shelf life of food products, such as¹ ²:

- Food preservation: Aurantium extract has been shown to exhibit antioxidant and antimicrobial properties, making it a potential natural preservative for extending the shelf life of food products like yoghurt and fish.

Keep in mind that the shelf life may vary depending on the specific product formulation, storage conditions, and handling practices. Always check the product label or consult with the manufacturer for specific guidance.

What should the label claim for Aurantium Extract Manufactured by MEDIOCON INC   Include?

The label claim for Aurantium extract should include:

- Product Name: Accurate and clear product name

- Active Ingredients: List of active ingredients, such as synephrine

- Concentration: Concentration of active ingredients (e.g., percentage or mg per serving)

- Dosage Instructions: Recommended dosage and usage guidelines

- Warning Statements: Any relevant warnings or cautions, such as potential interactions or side effects

- Storage Instructions: Proper storage conditions to maintain product quality

- Expiration Date: Manufacturing date and expiration date or shelf life

- Manufacturer Information: Manufacturer's name, address, and contact information

- Certifications: Any relevant certifications, such as GMP or third-party testing

- Claims: Any specific claims, such as weight loss or digestive support, should be substantiated by scientific evidence.

 

The label should comply with regulatory requirements and industry standards to ensure product safety and efficacy.

Where can Aurantium Extract Manufactured by MEDIOCON INC are procured?

Aurantium Extract Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

FOR API

MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com           

GST No: 27DHUPM2366D1ZZ

For Dosage Forms :

- Online Marketplaces: You can find Aurantium Extract Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in your area for Aurantium Extract Manufactured by MEDIOCON INC products.

Remember to ensure the quality and authenticity of the Aurantium Extract Manufactured by MEDIOCON INC product, regardless of the procurement source.