Black Sesame Extract 84650-60-2 Manufactured Exporter MEDIOCON INC

 

 

Black Sesame Extract Manufactured by MEDIOCON INC     

 

   Name: Black Sesame Extract

 

   CAS No:  84650-60-2

 

Molecular Weight: NA

Molecular formula:   NA

Synonyms:  Camellia sinensis extract, tea polyphenols, black camellia sinensis l. leaf extract, and Theaflavin.

Appearance:  Dark brown to reddish-brown powder.

 Solubility :  Generally water soluble.

Use :

Black tea extract has various uses due to its potential health benefits and antioxidant properties. Some of these uses include:

 

1. Antioxidant supplement: Rich in antioxidants like theaflavins and catechins.

2. Cardiovascular health: May help lower cholesterol and blood pressure.

3. Anti-inflammatory: May reduce inflammation and improve overall health.

4. Antimicrobial: Exhibits antimicrobial properties, potentially aiding in infection prevention.

5. Weight management: May aid in weight loss and metabolic health.

6. Skincare: Used in some skincare products for its antioxidant and anti-inflammatory properties.

7. Digestive health: May support gut health and digestion.

 How is  Black Tea Extract manufactured by MEDIOCON INC Synthesized?

Black Tea Extract is typically produced through:

1. Grinding or milling: Sunflower seeds are ground into a fine powder.

2. Roasting (optional): Seeds may be roasted before grinding for flavor enhancement.

3. Cold-pressing (optional): Oil may be extracted, leaving a defatted powder.

The process involves:

1. Cleaning and sorting seeds

2. Grinding or milling

3. Sifting or sieving

4. Packaging Black tea extract synthesis typically involves a green synthesis method, utilizing black tea as a reducing and stabilizing agent. Here's a breakdown of the process:

Synthesis Process

- Preparation of Black Tea Extract: Black tea powder is added to distilled water, boiled, and maintained at a temperature of around 70°C for 30 minutes. The resulting extract is then cooled and filtered.

- Reduction and Stabilization: The black tea extract is used as a reducing agent to synthesize nanoparticles, such as copper, zinc oxide, or iron oxide. The extract's organic compounds, like gallic acid, act as stabilizing agents, allowing for the formation of nanoparticles.

- Characterization: The synthesized nanoparticles are characterized using techniques like UV-visible spectrophotometry, X-ray diffraction (XRD), scanning electron microscopy (SEM), and thermogravimetric analysis (TGA).

 

Applications

Black tea extract-mediated synthesis has been used to create various nanoparticles, including:

- Copper nanoparticles: Synthesized using black tea extract and copper sulphate, these nanoparticles have potential applications in fields like medicine and electronics.

- Zinc oxide nanoparticles: Prepared using black tea extract and zinc nitrate, these nanoparticles have been explored for their antimicrobial and photocatalytic properties.

- Iron oxide nanoparticles: Synthesized using black tea extract and ferric nitrate, these nanoparticles have potential applications in environmental remediation and biomedical fields.

 

Benefits

The green synthesis method using black tea extract offers several advantages, including⁴:

- Environmental friendliness: The use of natural extracts reduces the need for harsh chemicals and minimizes environmental impact.

- Cost-effectiveness: The process is relatively inexpensive compared to traditional synthesis methods.

- Ease of scale-up: The green synthesis method can be easily scaled up for large-scale production.

What are the different  dosage forms  of   Black Tea Extract Manufactured  by  MEDIOCON INC?

Black tea extract is available in various dosage forms, including:

 

1. Capsules: Containing standardized extracts in powder or oil form.

2. Tablets: Compressed powder or granules containing black tea extract.

3. Powder: Loose powder for mixing with food or beverages.

4. Liquid Extract: Concentrated liquid form for oral consumption.

5. Tea Bags: Dried black tea leaves or extracts in tea bags for infusion.

6. Softgels: Gelatin or vegetarian capsules containing black tea extract in oil form.

7. Granules: Powdered extract in granule form for mixing with food or water.

 

These dosage forms cater to different preferences and needs, such as convenience, ease of consumption, and precise dosing. Always follow the recommended dosage and consult a healthcare professional if necessary.

  How Black Tea Extract Manufactured by MEDIOCON INC   Dosage Forms are prepared?

The preparation of black tea extract dosage forms involves several steps:

Preparation Steps

1. Extraction: Black tea leaves are extracted using solvents like water, ethanol, or a combination of both to obtain the desired compounds.

2. Concentration: The extract is then concentrated through evaporation, freeze-drying, or spray drying to remove excess solvent.

3. Standardization: The concentrated extract is standardized to ensure a consistent level of active compounds, such as theaflavins and catechins.

4. Formulation: The standardized extract is then formulated into various dosage forms, such as capsules, tablets, or powders, using excipients like fillers, binders, and lubricants.

5. Manufacturing: The formulated dosage form is manufactured using equipment like capsule fillers, tablet presses, or powder fillers.

Dosage Form-Specific Preparation

- Capsules: The extract is filled into gelatin or vegetarian capsules, often with additional ingredients like oils or fillers.

- Tablets: The extract is mixed with excipients and compressed into tablets using a tablet press.

- Powders: The extract is mixed with excipients and filled into powder containers or sachets.

- Liquid Extracts: The concentrated extract is diluted with a solvent, such as water or glycerin, to create a liquid dosage form.

Quality Control

Throughout the preparation process, quality control measures are taken to ensure the final product meets the required standards for purity, potency, and safety.

What are the appropriate Dosage forms of Black Tea Extract Manufactured  by  MEDIOCON   INC?                

The appropriate dosage forms of black tea extract depend on the intended use, individual preferences, and needs. Here are some common dosage forms and their suitability:

Suitable Dosage Forms

1. Capsules or Tablets: Suitable for standardized extracts, providing a precise dose of active compounds like theaflavins and catechins.

2. Powder: Convenient for mixing with food or beverages, allowing for flexible dosing.

3. Liquid Extract: Suitable for those who prefer a liquid form or have difficulty swallowing capsules or tablets.

4. Tea Bags: Suitable for traditional tea consumption, providing a relaxing and enjoyable experience.

Considerations

When choosing a dosage form, consider factors like:

- Convenience: Capsules or tablets may be more convenient for daily use.

- Dose flexibility: Powders or liquid extracts may offer more flexibility in dosing.

- Personal preference: Tea bags or liquid extracts may be preferred for their taste or ease of use.

- Standardization: Look for standardized extracts to ensure consistent levels of active compounds.

Consultation

Consult with a healthcare professional to determine the most suitable dosage form and dosage for your specific needs and health status.

When should Black Tea Extract Manufactured by MEDIOCON INC be taken?

The optimal time to take black tea extract depends on the individual's goals and needs. Here are some considerations:

 

Timing Options

1. With meals: Taking black tea extract with meals may help with digestion and reduce potential stomach upset.

2. In the morning: Consuming black tea extract in the morning may help boost energy and mental clarity.

3. Before or after exercise: Taking black tea extract before or after exercise may aid in weight management, improve exercise performance, or support recovery.

4. As directed: Follow the recommended dosage and timing instructions provided by the manufacturer or healthcare professional.

 

Considerations

When deciding when to take black tea extract, consider factors like:

 

- Caffeine sensitivity: If you're sensitive to caffeine, consider taking black tea extract earlier in the day to avoid interfering with sleep.

- Stomach sensitivity: If you experience stomach upset, try taking black tea extract with food or a meal.

- Interactions with medications: Consult with a healthcare professional to determine the best timing for taking black tea extract if you're taking medications.

 

Consultation

Consult with a healthcare professional to determine the most suitable timing for taking black tea extract based on your individual needs and health status.

 What are the effects And Side effects of Black Tea Extract Manufactured by MEDIOCON INC?

Black tea extract has various effects and potential side effects:

 

Effects

1. Antioxidant properties: May help protect against cell damage and oxidative stress.

2. Cardiovascular health: May help lower cholesterol and blood pressure.

3. Anti-inflammatory: May reduce inflammation and improve overall health.

4. Antimicrobial: Exhibits antimicrobial properties, potentially aiding in infection prevention.

5. Weight management: May aid in weight loss and metabolic health.

Potential Side Effects

1. Caffeine-related side effects: Anxiety, jitteriness, insomnia, or increased heart rate due to caffeine content.

2. Stomach upset: Nausea, vomiting, or diarrhea, especially when consumed in large quantities.

3. Interactions with medications: May interact with certain medications, such as blood thinners or certain antidepressants.

4. Allergic reactions: Rarely, some individuals may experience allergic reactions, such as hives or itching.

Precautions

1. Pregnancy and breastfeeding: Consult a healthcare professional before using black tea extract.

2. Caffeine sensitivity: Individuals sensitive to caffeine may want to start with low doses or avoid black tea extract.

3. Underlying health conditions: Consult a healthcare professional if you have underlying health conditions or take medications.

Consultation

Consult with a healthcare professional to discuss potential effects, side effects, and interactions, and to determine the best course of use for your individual needs and health status.

  How is Black Tea Extract Manufactured by MEDIOCON  INC  Tested Qualitatively?

Black tea extract is tested qualitatively using various methods to ensure its quality, purity, and potency. Here are some common qualitative testing methods:

Testing Methods

1. High-Performance Liquid Chromatography (HPLC): Used to identify and quantify specific compounds, such as theaflavins and catechins.

2. Gas Chromatography-Mass Spectrometry (GC-MS): Used to identify and quantify volatile compounds and contaminants.

3. Ultraviolet-Visible Spectroscopy (UV-Vis): Used to determine the total polyphenol content and antioxidant activity.

4. Fourier Transform Infrared Spectroscopy (FTIR): Used to identify functional groups and detect contaminants.

5. Microbial Testing: Used to ensure the extract is free from microbial contaminants, such as bacteria, yeast, and mold.

Parameters Tested

1. Theaflavin and catechin content: Ensures the extract meets the required standards for these bioactive compounds.

2. Purity: Verifies the absence of contaminants, such as heavy metals, pesticides, and microbial contaminants.

3. Potency: Ensures the extract has the required level of bioactive compounds.

4. Antioxidant activity: Measures the extract's ability to neutralize free radicals.

Importance

Qualitative testing of black tea extract ensures:

1. Quality: Ensures the extract meets the required standards for safety, purity, and potency.

2. Efficacy: Ensures the extract has the desired biological effects.

3. Safety: Ensures the extract is safe for consumption and free from contaminants.

Certification

Look for certifications like:

1. Good Manufacturing Practice (GMP): Ensures the extract is manufactured according to strict quality standards.

2. ISO 9001: Ensures the manufacturer has a quality management system in place.

Certifications and qualitative testing ensure the black tea extract meets the required standards for quality, safety, and efficacy.

Which tests are performed on Black Tea Extract Manufactured by  MEDIOCON INC?

Black tea extract undergoes various tests to ensure its quality, safety, and efficacy. Here are some common tests performed:

Physical and Chemical Tests

1. Appearance: Visual inspection for color, texture, and consistency.

2. Solubility: Test for solubility in water or other solvents.

3. pH: Measurement of the extract's pH level.

4. Moisture content: Determination of the extract's moisture content.

5. Ash content: Measurement of the extract's ash content.

Analytical Tests

1. HPLC (High-Performance Liquid Chromatography): Analysis of theaflavins, catechins, and other bioactive compounds.

2. UV-Vis spectroscopy: Measurement of total polyphenol content and antioxidant activity.

3. GC-MS (Gas Chromatography-Mass Spectrometry): Identification and quantification of volatile compounds.

Microbiological Tests

1. Total plate count: Determination of the total microbial load.

2. Yeast and mold count: Detection of yeast and mold contamination.

3. Pathogen testing: Testing for pathogens like E. coli, Salmonella, and Staphylococcus aureus.

Contaminant Testing

1. Heavy metal testing: Detection of heavy metals like lead, mercury, and arsenic.

2. Pesticide testing: Detection of pesticide residues.

3. Aflatoxin testing: Detection of aflatoxins, toxic compounds produced by certain molds.

Other Tests

1. Antioxidant activity: Measurement of the extract's antioxidant capacity.

2. Stability testing: Evaluation of the extract's stability over time.

These tests ensure the black tea extract meets quality, safety, and efficacy standards.

 

What are the challenges in Manufacturing of Black Tea Extract Manufactured by MEDIOCON   INC API?

The manufacturing of Black Tea Extract API (Active Pharmaceutical Ingredient) poses several challenges:

Challenges

1. Raw material variability: Variations in tea quality, climate, and processing conditions can affect the extract's composition and potency.

2. Standardization: Ensuring consistent levels of bioactive compounds, such as theaflavins and catechins, can be challenging.

3. Extraction efficiency: Optimizing extraction methods to maximize yield and minimize degradation of bioactive compounds.

4. Purification: Removing impurities and contaminants while preserving bioactive compounds.

5. Stability: Maintaining the stability of bioactive compounds during processing, storage, and transportation.

6. Scalability: Scaling up production while maintaining consistency and quality.

7. Regulatory compliance: Meeting regulatory requirements for API manufacturing, such as GMP (Good Manufacturing Practice) guidelines.

8. Quality control: Implementing robust quality control measures to ensure batch-to-batch consistency.

Solutions

1. Standardized extraction protocols: Developing and implementing standardized extraction protocols.

2. Advanced analytical techniques: Utilizing advanced analytical techniques, such as HPLC and GC-MS, for quality control.

3. Process optimization: Optimizing processing conditions to minimize degradation of bioactive compounds.

4. Quality assurance: Implementing quality assurance measures, such as GMP and ISO 9001, to ensure consistency and quality.

By addressing these challenges, manufacturers can produce high-quality Black Tea Extract API that meets regulatory requirements and customer expectations.

What are the challenges in manufacturing of Black Tea Extract Manufactured by MEDIOCON  INC ’s Dosage forms?

The manufacturing of Black Tea Extract dosage forms poses several challenges:

Challenges

1. Standardization: Ensuring consistent levels of bioactive compounds in each dosage form.

2. Formulation: Developing a stable and bioavailable formulation that masks the bitter taste of black tea extract.

3. Excipient compatibility: Ensuring compatibility between the extract and excipients to maintain stability and efficacy.

4. Moisture sensitivity: Protecting the extract from moisture to prevent degradation and loss of potency.

5. Scale-up: Scaling up production while maintaining consistency and quality.

6. Regulatory compliance: Meeting regulatory requirements for dosage form manufacturing, such as GMP guidelines.

7. Quality control: Implementing robust quality control measures to ensure batch-to-batch consistency.

8. Stability testing: Conducting stability testing to ensure the dosage form remains effective over time.

Solutions

1. Optimized formulation: Developing optimized formulations that ensure stability, bioavailability, and palatability.

2. Advanced manufacturing technologies: Utilizing advanced manufacturing technologies, such as granulation and encapsulation, to improve consistency and quality.

3. Robust quality control: Implementing robust quality control measures, such as in-process testing and finished product testing.

4. Stability testing protocols: Developing stability testing protocols to ensure the dosage form remains effective over time.

By addressing these challenges, manufacturers can produce high-quality Black Tea Extract dosage forms that meet regulatory requirements and customer expectations.

What is the Packing for Black Tea Extract Manufactured by MEDIOCON INC?

The packaging for Black Tea Extract typically includes:

Packaging Options

1. Drums or barrels: Large quantities of extract are often packaged in drums or barrels for industrial use.

2. Bags or pouches: Smaller quantities of extract can be packaged in bags or pouches for commercial use.

3. Capsules or tablets: Black Tea Extract can be formulated into capsules or tablets and packaged in bottles or blister packs.

4. Powder packets: Powdered extract can be packaged in single-serve packets or sachets.

Packaging Materials

1. Plastic containers: Plastic containers, such as HDPE or PET, are commonly used for packaging Black Tea Extract.

2. Glass containers: Glass containers can be used for packaging extract, especially for smaller quantities.

3. Foil packets: Foil packets can be used to package extract, providing a barrier against moisture and light.

Packaging Considerations

1. Moisture protection: Packaging should protect the extract from moisture to prevent degradation.

2. Light protection: Packaging should protect the extract from light to prevent degradation of bioactive compounds.

3. Tamper-evidence: Packaging should be tamper-evident to ensure product integrity.

Labeling

1. Product information: Labels should include product information, such as ingredients, instructions for use, and storage conditions.

2. Batch number and expiration date: Labels should include the batch number and expiration date to ensure product traceability and quality control.

Proper packaging and labeling ensure the quality and safety of Black Tea Extract products.

What is shelf life Of Black Tea Extract Manufactured by MEDIOCON INC? 

The shelf life of Black Tea Extract can vary depending on several factors, including:

 

Factors Affecting Shelf Life

1. Storage conditions: Temperature, humidity, and light exposure can affect the shelf life of the extract.

2. Packaging: The type of packaging and its ability to protect the extract from moisture, light, and oxygen can impact shelf life.

3. Formulation: The formulation of the extract, including the presence of stabilizers or preservatives, can influence shelf life.

 

Typical Shelf Life

1. Powdered extract: 2-3 years when stored in a cool, dry place, away from direct sunlight.

2. Liquid extract: 1-2 years when stored in a cool, dry place, away from direct sunlight, and refrigerated if recommended.

3. Capsules or tablets: 2-3 years when stored in a cool, dry place, away from direct sunlight.

 

Storage Recommendations

1. Cool, dry place: Store the extract in a cool, dry place, away from direct sunlight and heat sources.

2. Tight container: Store the extract in a tightly sealed container to protect it from moisture and air.

3. Refrigeration: If recommended, store the extract in the refrigerator to prolong shelf life.

Expiration Date

The expiration date or "best by" date on the label indicates the manufacturer's guarantee of the product's potency and quality up to that date, when stored properly.

 

What should the label claim for Black Tea Extract Manufactured by MEDIOCON INC   Include?

The label claim for Black Tea Extract should include:

Required Information

1. Product name: The name of the product, including the type of extract (e.g., Black Tea Extract).

2. Ingredients: A list of ingredients, including the extract itself and any other components.

3. Net weight or quantity: The net weight or quantity of the product.

4. Directions for use: Instructions on how to use the product, including dosage and frequency.

5. Warning or caution statements: Any warning or caution statements related to potential side effects, interactions, or allergies.

6. Storage conditions: Recommendations for storing the product, including temperature, humidity, and light exposure.

7. Expiration date or batch number: The expiration date or batch number to ensure product traceability and quality control.

 

Optional Claims

1. Standardization: A claim stating the extract is standardized to a specific level of bioactive compounds (e.g., theaflavins).

2. Potency: A claim stating the potency of the extract, such as the amount of bioactive compounds per serving.

3. Certifications: Claims related to certifications, such as GMP (Good Manufacturing Practice) or organic certification.

4. Health benefits: Claims related to potential health benefits, such as antioxidant or cardiovascular support, if substantiated by scientific evidence.

Regulatory Compliance

The label claim should comply with relevant regulatory requirements, such as those set by the FDA or other national regulatory agencies.

Where can Black Tea Extract Manufactured by MEDIOCON INC are procured?

Black Tea Extract Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

FOR API

MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com           

GST No: 27DHUPM2366D1ZZ

For Dosage Forms :

- Online Marketplaces: You can find Black Tea Extract Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in your area for Black Tea Extract Manufactured by MEDIOCON INC products.

Remember to ensure the quality and authenticity of the Black Tea Extract Manufactured by MEDIOCON INC product, regardless of the procurement source.