Melatonin 73-31-4 Manufacturer Exporter MEDIOCON INC

 

 

Melatonin Manufactured by MEDIOCON INC     

 

·           Name: Melatonin

 

·           CAS No: 73-31-4

  

·        Molecular Weight: 232.27 g/mol

 

·          Molecular formula:   C₁₃H₁₆O₂N₂

 

·        Synonyms:  N-Acetyl-2-Methoxytriptamine 

                                               

·        Appearance: White-cream to yellowish crystalline powder.

·           Solubility :   poorly soluble in water, slightly soluble in benzene and very slightly soluble in petroleum ether

·            Use :

Melatonin is used for:

1. Sleep regulation: Improving sleep quality, duration, and onset.

2. Insomnia treatment: Managing insomnia, especially in older adults.

3. Circadian rhythm regulation: Adjusting sleep-wake cycles.

4. Antioxidant properties: Potential antioxidant benefits.

5. Mood support: Some studies suggest melatonin may help with anxiety and depression.

 

·              How is  Melatonin manufactured by MEDIOCON INC Synthesized?

 Melatonin is synthesized in the body from the amino acid tryptophan through a multi-step process:

1. Tryptophan conversion: Tryptophan is converted into serotonin.

2. Serotonin conversion: Serotonin is converted into N-acetylserotonin.

3. Melatonin synthesis: N-acetylserotonin is converted into melatonin by the enzyme hydroxyindole O-methyltransferase.

This process occurs primarily in the pineal gland. Melatonin can also be synthesized industrially for commercial production.

 

·        What are the different  dosage forms  of   Melatonin Manufactured  by  MEDIOCON INC?

Melatonin is available in various dosage forms, including:

1. Tablets: Immediate-release or sustained-release tablets.

2. Capsules: Softgels or vegetarian capsules.

3. Gummies: Chewable gummies, often flavored.

4. Liquid: Oral solutions or sublingual liquids.

5. Sublingual tablets: Dissolve under the tongue.

6. Extended-release formulations: Designed for prolonged release.

These dosage forms cater to different needs and preferences, such as ease of use, absorption rate, and release mechanism. Always follow the recommended dosage and consult a healthcare professional if needed.

·          How Melatonin  Manufactured by MEDIOCON INC   Dosage Forms are prepared?

 Melatonin dosage forms are prepared through various processes, including:

1. Tablets: Compression of melatonin powder with excipients.

2. Capsules: Filling capsules with melatonin powder or liquid.

3. Gummies: Mixing melatonin with gummy base, sweeteners, and flavorings.

4. Liquid: Dissolving melatonin in a suitable solvent.

The preparation process typically involves:

1. Material sourcing: Obtaining melatonin and excipients.

2. Formulation development: Determining optimal composition.

3. Manufacturing: Producing the dosage form.

4. Quality control: Testing for purity, potency, and stability.

Good Manufacturing Practices (GMP) ensure quality and safety.

·        What are the appropriate Dosage forms of Melatonin Manufactured  by  MEDIOCON   INC?                

 

Appropriate dosage forms of melatonin include:

1. Immediate-release tablets/capsules: For quick sleep onset.

2. Sustained-release tablets/capsules: For maintaining sleep throughout the night.

3. Sublingual tablets/liquids: For faster absorption.

4. Gummies: For ease of use, especially for children or those with swallowing difficulties.

The choice of dosage form depends on individual needs, such as sleep issues (insomnia, sleep maintenance) and personal preferences. Consult a healthcare professional for guidance. 

·            When should Melatonin Manufactured by MEDIOCON INC be taken?

Melatonin is typically taken:

1. 30-60 minutes before bedtime: To help regulate sleep-wake cycles and improve sleep quality.

2. At the same time each day: To establish a consistent sleep schedule.

However, the optimal timing may vary depending on individual needs and circumstances. Consult a healthcare professional for personalized guidance.

·            What are the effects And Side effects of Melatonin Manufactured by MEDIOCON INC?

Effects:

1. Regulates sleep-wake cycle: Improves sleep quality and duration.

2. Antioxidant properties: May help protect against oxidative stress.

3. Mood support: Some studies suggest melatonin may help with anxiety and depression.

Side effects:

1. Drowsiness: Common, especially during the day.

2. Headaches: Some people may experience headaches.

3. Dizziness: May cause dizziness or lightheadedness.

4. Nausea: Some individuals may experience nausea.

5. Interactions: May interact with medications, such as blood thinners.

Long-term use:

1. Dependence: Potential risk of dependence or withdrawal symptoms.

2. Hormone regulation: May affect hormone levels, including reproductive hormones.

Consult a healthcare professional before taking melatonin, especially if you have underlying medical conditions or take medications.

·          How is Melatonin Manufactured by MEDIOCON  INC  Tested Qualitatively?

Melatonin is tested qualitatively through:

1. High-Performance Liquid Chromatography (HPLC): Identifies and quantifies melatonin content.

2. Spectroscopy (IR, UV): Analyzes molecular structure and functional groups.

3. Mass Spectrometry (MS): Confirms molecular weight and structure.

These tests ensure melatonin's identity, purity, and quality. 

·           Which tests are performed on Melatonin Manufactured by  MEDIOCON INC ?

Tests performed on melatonin may include:

 

1. High-Performance Liquid Chromatography (HPLC): Verifies purity and potency.

2. Mass Spectrometry (MS): Confirms molecular structure and weight.

3. Infrared Spectroscopy (IR): Identifies molecular structure.

4. Ultraviolet Spectroscopy (UV): Analyzes absorption characteristics.

5. Microbial testing: Assesses microbial contamination.

6. Stability testing: Evaluates shelf life and storage conditions.

 

These tests ensure melatonin's quality, safety, and efficacy.

·        What are the challenges in Manufacturing of Melatonin Manufactured by MEDIOCON   INC API?

Challenges in manufacturing Melatonin API may include:

1. Purity control: Ensuring high purity and minimizing impurities.

2. Stability: Maintaining stability during production, storage, and transportation.

3. Scalability: Scaling up production while maintaining quality and consistency.

4. Regulatory compliance: Meeting regulatory requirements and standards.

5. Raw material sourcing: Sourcing high-quality raw materials.

6. Process optimization: Optimizing manufacturing processes for efficiency and yield.

7. Controlling particle size: Ensuring consistent particle size for optimal bioavailability.

Overcoming these challenges requires expertise, advanced technology, and strict quality control measures. 

·        What are the challenges in manufacturing of Melatonin Manufactured by MEDIOCON  INC ’s Dosage forms?

 

Challenges in manufacturing Melatonin dosage forms may include:

 

1. Formulation stability: Ensuring melatonin stability in the dosage form.

2. Content uniformity: Achieving consistent melatonin content.

3. Bioavailability: Optimizing bioavailability.

4. Excipient compatibility: Ensuring compatibility with other ingredients.

5. Manufacturing process: Scaling up production.

6. Regulatory compliance: Meeting regulatory requirements.

7. Quality control: Ensuring consistent quality.

Additionally, challenges may arise from:

1. Light sensitivity: Protecting melatonin from light degradation.

2. Moisture sensitivity: Controlling moisture levels.

Addressing these challenges requires expertise in formulation development and manufacturing.

·           What is the Packing for Melatonin Manufactured by MEDIOCON INC?

Melatonin packaging typically includes:

 

1. Bottles: Glass or plastic bottles with child-resistant caps.

2. Blister packs: Individual tablets or capsules in blister packs.

3. Foil packets: Single-dose packets.

4. Labeling: Clear labeling with dosage instructions, ingredients, and warnings.

 

Packaging considerations:

1. Light protection: Amber or opaque containers to protect from light.

2. Moisture control: Desiccants or moisture-resistant packaging.

3. Tamper-evidence: Tamper-evident seals or packaging.

Proper packaging ensures melatonin stability, safety, and efficacy.

 

·         What is shelf life Of Melatonin Manufactured by MEDIOCON INC? 

The shelf life of Melatonin typically ranges from:

 

1. 2-3 years: For tablets, capsules, or gummies stored properly.

2. Specific storage conditions: Cool, dry place, away from light and moisture.

Shelf life may vary depending on:

1. Formulation: Type of dosage form (e.g., tablet, liquid).

2. Storage conditions: Temperature, humidity, and light exposure.

3. Packaging: Quality and type of packaging material.

Always check the expiration date or "Best By" date on the label.

·        What should the label claim for Melatonin Manufactured by MEDIOCON INC   Include?

 The label claim for Melatonin should include:

1. Dosage instructions: Recommended dosage and frequency.

2. Ingredients: List of ingredients, including melatonin and any other active or inactive ingredients.

3. Warnings: Any relevant warnings, such as interactions with medications or potential side effects.

4. Expiration date: Clearly stated expiration date or "Best By" date.

5. Storage instructions: Recommendations for storage conditions (e.g., cool, dry place).

6. Net quantity: Amount of melatonin per serving and total number of servings.

7. Manufacturer information: Name and contact information of the manufacturer or distributor.

This information helps ensure safe and effective use of the product.

 

·        Where can Melatonin  Manufactured by MEDIOCON INC are procured?

Melatonin Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

1.      FOR API

 MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com           

 GST No: 27DHUPM2366D1ZZ

 

 

2.      For Dosage Forms :

     - Online Marketplaces: You can find Melatonin Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

 - Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in your area for Melatonin Manufactured by MEDIOCON INC products.

 Remember to ensure the quality and authenticity of the Melatonin Manufactured by MEDIOCON INC product, regardless of the procurement source.