Policosanol 142583-61-7 Manufacturer Exporter MEDIOCON INC

 

Policosanol Manufactured by MEDIOCON INC     

 

   Name: Policosanol

 

   CAS No:  142583-61-7

 

Molecular Weight: 418-422 g/mol

  Molecular formula:   NA

 

Synonyms:  Ateromixol

Appearance:  - A white or off-white powder Fine crystals or granules.

 

   Solubility :   Insoluble in water, Soluble in organic solvents like ethanol, chloroform, and           

                         other non-polar solvents

    Use :

Policosanol is often used for:

- Lowering cholesterol levels

- Improving cardiovascular health

- Antioxidant properties

- Potential benefits for intermittent claudication and atherosclerosis

 

Some people also use it for:

- Anti-inflammatory effects

- Improving blood flow

However, consult a healthcare professional before using Policosanol supplements, as results may vary and interactions with medications are possible.

 How is  Policosanol manufactured by MEDIOCON INC Synthesized?

Policosanol is typically derived from natural sources, such as:

- Sugarcane wax

- Bee wax

- Other plant-based waxes

The synthesis process involves:

1. Extraction of wax

2. Purification

3. Isolation of policosanol compounds (mainly octacosanol, triacontanol, and hexacosanol)

Some manufacturers may use different methods, such as:

- Solvent extraction

- Chromatography

- Crystallization

The resulting product is often a mixture of long-chain alcohols, which are believed to contribute to its potential health benefits.

What are the different  dosage forms  of   Policosanol Manufactured  by  MEDIOCON INC?

Policosanol is available in various dosage forms, including:

- Tablets

- Capsules

- Powders

These forms may contain different concentrations of Policosanol, such as:

- 5mg

- 10mg

- 20mg

Some products may also combine Policosanol with other supplements or nutrients. Always follow the recommended dosage and consult a healthcare professional before using.

  How Policosanol Manufactured by MEDIOCON INC   Dosage Forms are prepared?

The preparation of Policosanol dosage forms involves several steps:

- Tablets:

    1. Mixing Policosanol powder with excipients (e.g., binders, fillers)

    2. Granulation (if needed)

    3. Compression into tablets

- Capsules:

    1. Filling capsules with Policosanol powder or granules

    2. Adding excipients (e.g., fillers, lubricants) if necessary

    3. Sealing the capsules

- Powders:

    1. Mixing Policosanol powder with excipients (if needed)

    2. Filling containers or sachets

 

The specific process may vary depending on the manufacturer and desired product characteristics. Quality control measures ensure the final product meets standards.

What are the appropriate Dosage forms of Policosanol Manufactured  by  MEDIOCON   INC?                

The appropriate dosage forms of Policosanol can vary depending on the intended use and individual preferences. Common forms include:

1. Oral tablets: Convenient for precise dosing.

2. Capsules: Often used for supplements, may contain oils or powders.

3. Powders: Can be mixed with food or drinks, flexible dosing.

The choice of dosage form may depend on factors like:

- Desired dosage

- Ease of administration

- Individual tolerance

It's essential to follow the recommended dosage and consult a healthcare professional for personalized guidance.

When should Policosanol Manufactured by MEDIOCON INC be taken?

Policosanol is typically taken:

- With meals to enhance absorption

- Once or twice daily, depending on the product and individual needs

- At the same time each day for consistent effects

However, it's best to follow the specific instructions provided by the manufacturer or healthcare professional, as optimal timing may vary.

 What are the effects And Side effects of Policosanol Manufactured by MEDIOCON INC?

Effects:

1. Cholesterol reduction (LDL and total cholesterol)

2. Improved cardiovascular health

3. Antioxidant properties

4. Potential benefits for intermittent claudication and atherosclerosis

5. Anti-inflammatory effects

Side Effects:

1. Generally considered safe and well-tolerated

2. Possible side effects:

    - Headache

    - Dizziness

    - Gastrointestinal issues (e.g., nausea, diarrhea)

    - Weight loss

    - Skin reactions (rare)

3. Interactions with medications (e.g., anticoagulants, antiplatelet drugs) are possible

Precautions:

1. Consult a healthcare professional before using Policosanol, especially if pregnant, breastfeeding, or taking medications.

2. Monitor blood sugar levels if diabetic, as Policosanol may affect glucose levels.

Individual results and side effects may vary. Consult a healthcare professional for personalized guidance.

  How is Policosanol Manufactured by MEDIOCON  INC  Tested Qualitatively?

Policosanol is typically tested qualitatively using:

- High-Performance Liquid Chromatography (HPLC): To identify and quantify individual components.

- Gas Chromatography (GC): To analyze the composition and purity.

- Mass Spectrometry (MS): To confirm the identity of specific compounds.

These methods help ensure the quality, purity, and authenticity of Policosanol products.

   Which tests are performed on Policosanol Manufactured by  MEDIOCON INC ?

- High-Performance Liquid Chromatography (HPLC): To identify and quantify individual components, such as octacosanol, triacontanol, and hexacosanol.

- Gas Chromatography (GC): To analyze the composition and purity of Policosanol.

- Mass Spectrometry (MS): To confirm the identity of specific compounds and detect any impurities.

- Lipid Peroxidation Assays: To evaluate the antioxidant properties of Policosanol and its effects on LDL oxidation.

- Toxicity Tests: To assess the safety and potential side effects of Policosanol, including animal studies and clinical trials.

- Clinical Trials: To evaluate the efficacy and safety of Policosanol in humans, including its effects on cholesterol levels, blood pressure, and cardiovascular health.

What are the challenges in Manufacturing of Policosanol Manufactured by MEDIOCON   INC API?

The manufacturing of Policosanol Active Pharmaceutical Ingredient (API) poses several challenges, including:

- Raw Material Sourcing: Ensuring consistent quality and availability of natural sources like sugarcane wax or beeswax.

- Purification: Isolating and purifying individual long-chain alcohols (e.g., octacosanol, triacontanol) to meet quality standards.

- Process Optimization: Developing efficient extraction and purification processes to minimize costs and maximize yield.

- Quality Control: Ensuring batch-to-batch consistency and compliance with regulatory standards.

- Regulatory Compliance: Meeting varying regulatory requirements across different countries and regions.

- Scalability: Scaling up production while maintaining quality and efficiency.

 

These challenges require careful planning, process optimization, and quality control measures to ensure the production of high-quality Policosanol API.

What are the challenges in manufacturing of Policosanol Manufactured by MEDIOCON  INC ’s Dosage forms?

The manufacturing of Policosanol dosage forms poses several challenges, including:

- Poor water solubility: Policosanol's low water solubility can affect bioavailability and formulation.

- Particle size control: Ensuring consistent particle size is crucial for uniform dosage and bioavailability.

- Excipient compatibility: Selecting excipients that are compatible with Policosanol and do not affect its stability or bioavailability.

- Tableting or encapsulation issues: Overcoming challenges related to tablet compression, capsule filling, or powder flow.

- Stability and shelf-life: Ensuring the product remains stable and effective throughout its shelf-life.

- Regulatory compliance: Meeting regulatory requirements for quality, safety, and efficacy.

These challenges require careful formulation development, process optimization, and quality control measures to ensure the production of high-quality Policosanol dosage forms.

What is the Packing for Policosanol Manufactured by MEDIOCON INC?

Policosanol packaging typically involves:

- Bottles: Glass or plastic bottles with tight-fitting lids to protect from light and moisture.

- Capsules or tablets containers: Blister packs, bottles, or containers specifically designed for capsules or tablets.

- Labeling: Labels indicating product name, dosage, ingredients, and storage instructions.

- Protective packaging: Additional packaging materials (e.g., foam inserts) to prevent damage during shipping.

 

The specific packaging may vary depending on the manufacturer, product form (e.g., tablets, capsules, powder), and regulatory requirements.

What is shelf life Of Policosanol Manufactured by MEDIOCON INC? 

- Policosanol Extract from Sugarcane: 3 years, as indicated by a manufacturer based in India

- Policosanol + CoQ10 Supplements: minimum of 2 years, according to a US-based supplier

- LesstanoL Policosanol 60: minimum of 3 years, specified by a manufacturer of raw materials

- Nano Soma Policosanol Spray: 3 years, claimed by Forever Life Naturals, a US-based company

 

To maximize shelf life, it's essential to store Policosanol products in:

- Cool, dry environments

- Protection from heat sources and sunlight

- Airtight containers or packaging

What should the label claim for Policosanol Manufactured by MEDIOCON INC   Include?

The label claim for Policosanol should include:

- Product Name: Accurate and clear product identification.

- Active Ingredient: Specification of Policosanol and its concentration.

- Dosage Instructions: Clear guidelines on recommended dosage and usage.

- Net Weight or Quantity: Declaration of the product's net weight or quantity.

- Storage Instructions: Guidance on proper storage conditions (e.g., cool, dry place).

- Expiration Date: Indication of the product's shelf life.

- Manufacturer Information: Details about the manufacturer, including name and contact information.

- Warning or Caution Statements: Any relevant warnings or cautions related to use, especially for specific populations (e.g., pregnant women, individuals with certain health conditions).

 

These details ensure compliance with regulatory requirements and provide consumers with essential information for safe and effective use.

Where can Policosanol Manufactured by MEDIOCON INC are procured?

Policosanol Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

FOR API

MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com           

GST No: 27DHUPM2366D1ZZ

For Dosage Forms :

- Online Marketplaces: You can find Policosanol Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in your area for Policosanol Manufactured by MEDIOCON INC products.

Remember to ensure the quality and authenticity of the Policosanol Manufactured by MEDIOCON INC product, regardless of the procurement source.