Sophora Japonica Extract 90131-19-4 Manufactured by MEDIOCON INC

 

 

Sophora Japonica Extract Manufactured by MEDIOCON INC     

 

   Name: Sophora Japonica Extract

   CAS No:  90131-19-4

Molecular Weight:  590.6g/mol

Molecular formula:   NA

Synonyms:  Chinese scholar tree extract, Japanese pagoda tree extract, Huaihua extract (referring to the flowers), and Huaimi extract (referring to the flower buds)

Appearance:  a fine, reddish-brown to orange-colored powder.

 Solubility :  Soluble in water.

Use :

Sophora Japonica Extract has various uses due to its bioactive compounds, particularly rutin and quercetin:

Health Benefits

1. Antioxidant properties: Protects against oxidative stress and inflammation.

2. Cardiovascular health: Supports blood vessel health and may help lower blood pressure.

3. Anti-inflammatory effects: May help reduce inflammation and alleviate symptoms.

Skincare

1. Antioxidant-rich: Helps protect skin from environmental stressors.

2. Anti-aging benefits: May improve skin elasticity and reduce fine lines.

Traditional Medicine

1. Hemostatic properties: Traditionally used to stop bleeding.

2. Treatment of various ailments: Used in traditional medicine for its perceived health benefits.

Other Uses

1. Dye: The plant's flowers and fruits can be used as a natural dye.

2. Pharmaceutical applications: Used as a source of rutin and quercetin for pharmaceutical products.

When using Sophora Japonica Extract, consider factors like:

- Quality and purity: Ensure the extract is standardized and free of contaminants.

- Dosage and interactions: Consult with a healthcare professional for recommended dosages and potential interactions.

Sophora Japonica Extract's versatility makes it a valuable ingredient in various industries.

 How is  Sophora Japonica Extract manufactured by MEDIOCON INC Synthesized?

Sophora Japonica Extract is typically obtained through extraction from the plant's flowers, buds, or fruits, rather than chemical synthesis. The extraction process involves:

Extraction Process

1. Raw material selection: Selecting high-quality Sophora Japonica plant material.

2. Drying and grinding: Drying and grinding the plant material into a suitable form for extraction.

3. Solvent extraction: Using a suitable solvent (e.g., ethanol, water) to extract the desired compounds.

4. Filtration and concentration: Filtering and concentrating the extract to obtain the desired consistency.

Purification and Standardization

1. Purification techniques: Using techniques like chromatography or crystallization to purify the extract.

2. Standardization: Standardizing the extract to specific levels of bioactive compounds (e.g., rutin, quercetin).

The resulting extract can be used in various applications, including pharmaceuticals, dietary supplements, and cosmetics.

What are the different  dosage forms  of   Sophora Japonica ExtractManufactured  by  MEDIOCON INC?

Sophora Japonica Extract can be formulated into various dosage forms, including:

Oral Dosage Forms

1. Capsules: Containing powdered extract or standardized extract.

2. Tablets: Compressed tablets containing extract and excipients.

3. Liquid extracts: Liquid formulations for oral consumption.

Topical Dosage Forms

1. Creams: Topical creams containing extract for skin application.

2. Ointments: Semi-solid formulations for skin application.

3. Serums: Lightweight, concentrated serums for skin benefits.

Other Dosage Forms

1. Powders: Powdered extract for use in food, beverages, or supplements.

2. Teas: Herbal teas or infusions made from Sophora Japonica.

The choice of dosage form depends on the intended use, desired benefits, and target audience. Always follow the recommended dosage and usage instructions.

 How Sophora Japonica Extract Manufactured by MEDIOCON INC   Dosage Forms are prepared?

Sophora Japonica Extract dosage forms are prepared through various processes:

Oral Dosage Forms (e.g., Capsules, Tablets)

1. Extract preparation: Sophora Japonica Extract is prepared through extraction, filtration, and concentration.

2. Blending: The extract is blended with excipients (e.g., fillers, binders).

3. Granulation: The blend is granulated to improve flow and compression properties.

4. Capsule filling or tableting: The granules are filled into capsules or compressed into tablets.

Topical Dosage Forms (e.g., Creams, Ointments)

1. Extract preparation: Sophora Japonica Extract is prepared through extraction and concentration.

2. Emulsification: The extract is mixed with oils, emulsifiers, and other ingredients.

3. Cream or ointment formulation: The mixture is formulated into a cream or ointment base.

4. Filling and packaging: The final product is filled into containers.

Quality Control

1. Raw material testing: Testing the extract for purity and potency.

2. In-process testing: Monitoring the manufacturing process.

3. Final product testing: Testing the finished product for quality and stability.

 

The preparation process may vary depending on the specific dosage form and manufacturer.

What are the appropriate Dosage forms of Sophora Japonica Extract Manufactured  by  MEDIOCON   INC?                

The appropriate dosage forms of Sophora Japonica Extract depend on the intended use and desired benefits. Here are some common dosage forms:

For Cardiovascular Health

1. Capsules: Containing standardized extract with rutin and quercetin.

2. Tablets: Formulated with extract and other ingredients to support cardiovascular health.

For Antioxidant and Anti-Inflammatory Benefits

1. Capsules: Containing extract with high levels of antioxidants.

2. Powders: For adding to food or beverages.

For Skincare

1. Topical creams: Formulated with extract and other skincare ingredients.

2. Serums: Lightweight, concentrated serums with antioxidant properties.

For Traditional Use

1. Teas: Herbal teas or infusions made from Sophora Japonica.

2. Tinctures: Liquid extracts for oral use.

The dosage form and strength may vary depending on the specific product and manufacturer. Always follow the recommended dosage and usage instructions.

When should Sophora Japonica Extract Manufactured by MEDIOCON INC be taken?

The timing of taking Sophora Japonica Extract depends on the intended use and individual needs. Here are some general guidelines:

For Cardiovascular Health

1. With meals: Taking with meals may enhance absorption and minimize stomach upset.

For Antioxidant Benefits

1. Anytime: Can be taken at any time of day, with or without food.

For Skincare

1. Topical application: Apply topically as directed, usually morning and night.

General Recommendations

1. Follow label instructions: Adhere to the recommended dosage and timing on the product label.

2. Consult a healthcare professional: If you have specific health concerns or questions.

 

It's essential to note that individual results may vary, and the optimal timing may depend on the specific product and individual needs.

 What are the effects And Side effects of Sophora Japonica ExtractManufactured by MEDIOCON INC?

Sophora Japonica Extract has various effects and potential side effects:

 

Effects:

- Cardiovascular Health: Supports heart health by regulating blood pressure, improving blood vessel function, and reducing the risk of heart disease.

- Anti-Inflammatory Benefits: Reduces inflammation, providing relief from arthritis, joint pain, and skin inflammation.

- Antioxidant Activity: Neutralizes harmful free radicals, reducing oxidative stress and potentially slowing down the aging process.

- Immune System Boost: Strengthens the immune system, helping the body fight off infections and maintain overall health.

- Skin Health: Improves skin health by reducing redness, irritation, and signs of aging due to its anti-inflammatory and antioxidant properties.

 

Side Effects:

- Gastrointestinal Upset: Mild stomach discomfort or diarrhea, particularly when taken on an empty stomach.

- Allergic Reactions: Individuals with allergies to plants in the Fabaceae family may experience allergic reactions, ranging from mild skin irritation to severe symptoms.

- Interactions with Medications: May interact with blood thinners, anti-inflammatory drugs, or other cardiovascular medications.

- Pregnancy and Breastfeeding: Possibly unsafe during pregnancy and breastfeeding due to limited research.

 

Precautions:

- Start with a lower dose: Observe your body's response and discontinue use if adverse reactions occur.

- Consult a healthcare professional: Before using Sophora Japonica Extract, especially if you have underlying health conditions or are taking medications

  How is Sophora Japonica Extract Manufactured by MEDIOCON  INC  Tested Qualitatively?

Sophora Japonica Extract is tested qualitatively using various analytical techniques to ensure its quality, purity, and potency. Some common methods include:

Analytical Techniques

1. High-Performance Liquid Chromatography (HPLC): Separates and identifies bioactive compounds like rutin and quercetin.

2. Thin-Layer Chromatography (TLC): Identifies and separates compounds based on their mobility.

3. Gas Chromatography (GC): Analyzes volatile compounds.

4. Mass Spectrometry (MS): Identifies and quantifies compounds based on their mass-to-charge ratio.

Quality Control Parameters

1. Purity: Testing for contaminants, heavy metals, and adulterants.

2. Potency: Measuring the concentration of bioactive compounds.

3. Identity: Verifying the extract's botanical identity.

Testing Methods

1. Standardization: Ensuring consistent levels of bioactive compounds.

2. Fingerprinting: Creating a unique chromatographic profile for the extract.

 

These tests help ensure the extract meets quality standards and is safe for use in various applications.

   Which tests are performed on Sophora Japonica Extract Manufactured by  MEDIOCON INC ?

Sophora Japonica Extract undergoes various tests to ensure its quality, purity, and potency. Some common tests include:

Chemical Tests

1. HPLC (High-Performance Liquid Chromatography): Measures the content of bioactive compounds like rutin and quercetin.

2. UV-Vis Spectroscopy: Analyzes the extract's absorption spectrum.

Physical Tests

1. Appearance: Verifies the extract's color, texture, and appearance.

2. Solubility: Tests the extract's solubility in various solvents.

Purity and Contamination Tests

1. Heavy Metal Analysis: Detects the presence of heavy metals like lead, mercury, and arsenic.

2. Microbial Contamination: Tests for the presence of microorganisms like bacteria, yeast, and mold.

Standardization Tests

1. Bioactive Compound Content: Measures the content of specific bioactive compounds.

2. Potency: Verifies the extract's potency and effectiveness.

 

These tests help ensure the extract meets quality standards and is safe for use in various applications.

What are the challenges in Manufacturing of Sophora Japonica Extract Manufactured by MEDIOCON   INC API?

Manufacturing Sophora Japonica Extract API poses several challenges, including¹ ² ³:

- Extraction difficulties: Obtaining high-quality extract with consistent bioactive component levels requires proper techniques.

- Quality control: Ensuring purity, potency, and consistency of the extract is crucial.

- Regulatory compliance: Meeting regulatory requirements for pharmaceuticals, cosmetics, and food supplements can be complex.

- Raw material sourcing: Sourcing high-quality Sophora Japonica flowers or raw materials is essential.

- Advanced extraction techniques: Utilizing suitable extraction methods to preserve bioactive compounds.

- Standardization: Standardizing the extract to specific levels of bioactive compounds like rutin and quercetin.

- Logistics and supply chain management: Managing the supply chain efficiently to maintain product quality and meet demand.

 

To overcome these challenges, manufacturers can:

- Implement strict quality control measures: Ensure purity, potency, and consistency of the extract.

- Invest in research and development: Improve extraction techniques and standardization methods.

- Collaborate with regulatory experts: Ensure compliance with regulatory requirements.

- Develop strong supply chain relationships: Source high-quality raw materials and manage logistics efficiently.

What are the challenges in manufacturing of Sophora Japonica Extract Manufactured by MEDIOCON  INC ’s Dosage forms?

Manufacturing Sophora Japonica Extract dosage forms poses several challenges, including:

Formulation Challenges

1. Stability issues: Ensuring the extract's stability in various formulations.

2. Solubility: Achieving optimal solubility of the extract in different dosage forms.

Manufacturing Challenges

1. Consistency: Maintaining consistent quality and potency of the extract in each batch.

2. Scalability: Scaling up production while maintaining quality and consistency.

Regulatory Challenges

1. Compliance: Meeting regulatory requirements for pharmaceuticals, cosmetics, or food supplements.

2. Documentation: Maintaining detailed documentation of manufacturing processes and quality control.

Quality Control Challenges

1. Testing and validation: Ensuring the dosage form meets quality and potency standards.

2. Raw material variability: Managing variability in raw material quality and composition.

 

To overcome these challenges, manufacturers can:

1. Implement robust quality control measures: Ensure consistency and quality of the extract and dosage forms.

2. Optimize formulation and manufacturing processes: Improve stability, solubility, and scalability.

3. Collaborate with regulatory experts: Ensure compliance with regulatory requirements.

4. Invest in research and development: Improve extraction techniques, formulation, and manufacturing processes.

What is the Packing for Sophora Japonica Extract Manufactured by MEDIOCON INC?

Sophora Japonica Extract packing options vary depending on the manufacturer and quantity required. Here are some common packing specifications:

- Drum Packing: 25kg/barrel or drum, suitable for bulk quantities

- Carton Packing: 10kg/25kg/carton, ideal for smaller to medium-sized quantities

- Foil Bag Packing: 1kg/5kg/10kg/bag, suitable for smaller quantities or research purposes

- Paper-Drum Packing: Packing in paper drums with two food-grade poly bags inside, net weight 25kg/drum, ensuring safe storage and transportation

Some manufacturers may offer customized packing options based on specific requirements. It's essential to verify packing details with the supplier or manufacturer to ensure the product meets your needs

What is shelf life Of Sophora Japonica Extract Manufactured by MEDIOCON INC? 

Sophora Japonica Extract typically has a shelf life of 2 years when stored properly. To maintain its potency and quality, it's essential to store it in.

- Cool and dry place: Away from direct sunlight and heat sources

- Well-closed containers: Prevent moisture and air exposure

- Constant low temperature: Avoid extreme temperature fluctuations

Proper storage conditions help preserve the extract's bioactive compounds, such as Rutin  and Quercetin, ensuring its effectiveness and safety for use in various applications, including pharmaceuticals, cosmetics, and food products.

What should the label claim for Sophora Japonica Extract Manufactured by MEDIOCON INC   Include?

The label claim for Sophora Japonica Extract should include:

- Product Name: Sophora Japonica Extract or specific product name

- Active Ingredients: Rutin and quercetin content (e.g., "Standardized to contain 10% rutin and 5% quercetin")

- Net Weight: Quantity of extract in the package

- Recommended Use: Intended use (e.g., dietary supplement, skincare)

- Recommended Dosage: Suggested dosage or usage instructions

- Storage Instructions: Guidelines for storing the extract (e.g., cool, dry place)

- Caution/Warnings: Any relevant warnings or cautions (e.g., "Consult a healthcare professional before use")

- Manufacturer Information: Name and contact details of the manufacturer or distributor

- Batch Number: Batch or lot number for quality control and tracking

- Expiry Date: Shelf life or expiration date

The label claim should be accurate, clear, and compliant with regulatory requirements. It's essential to ensure the label information is consistent with the product's specifications and intended use.

Where can Sophora Japonica Extract Manufactured by MEDIOCON INC are procured?

Sophora Japonica Extract Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

FOR API

MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com           

GST No: 27DHUPM2366D1ZZ

For Dosage Forms :

- Online Marketplaces: You can find Sophora Japonica Extract Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in your area for Sophora Japonica Extract Manufactured by MEDIOCON INC products.

Remember to ensure the quality and authenticity of the Sophora Japonica Extract Manufactured by MEDIOCON INC product, regardless of the procurement source.