Spinach Extract 90131-25-2 Manufacturer Exporter MEDIOCON INC

 

 

Spinach Extract Manufactured by MEDIOCON INC     

 

   Name: Spinach Extract

 

   CAS No:  90131-25-2

 

Molecular Weight:  NA

Molecular formula:   NA

Synonyms:  Appethyl, Spisar, Solarplast, and Quickhemo.

Appearance:  a vibrant green fine powder, a lighter yellow-brown powder.

 Solubility :  some are water-soluble, often due to the presence of vitamins and other hydrophilic compounds, others, such as those rich in apolar components like chlorophyll and lutein, are oil-soluble.

Use :

Spinach extract is used for various purposes due to its nutritional and bioactive compounds, including:

Health Benefits

1. Antioxidant properties: Rich in antioxidants like beta-carotene and lutein, which help protect cells from damage.

2. Eye health: Supports eye health and may reduce the risk of age-related macular degeneration.

3. Anti-inflammatory effects: May help reduce inflammation and oxidative stress.

Uses

1. Dietary supplements: Available in capsules, tablets, or powders to support overall health.

2. Functional foods: Added to foods and beverages for nutritional enhancement.

3. Skincare: Used in skincare products for its antioxidant and anti-inflammatory properties.

Potential Benefits

1. Cardiovascular health: May support heart health due to its antioxidant and anti-inflammatory effects.

2. Immune system support: May help boost the immune system.

When using spinach extract, it's essential to follow recommended dosages and consult with a healthcare professional if necessary.

 How is  Spinach Extract manufactured by MEDIOCON INC Synthesized?

Spinach extract is typically obtained through various extraction methods, rather than synthesis. Here are some common extraction methods:

Extraction Methods

1. Solvent extraction: Using solvents like ethanol or water to extract bioactive compounds.

2. Cold pressing: Mechanical extraction of juice or oil from spinach leaves.

3. Enzymatic extraction: Using enzymes to break down cell walls and release bioactive compounds.

4. Supercritical fluid extraction: Using high-pressure carbon dioxide to extract compounds.

Processing Steps

1. Harvesting: Fresh spinach leaves are harvested and cleaned.

2. Drying: Leaves may be dried to remove excess moisture.

3. Grinding: Leaves are ground into a fine powder.

4. Extraction: Bioactive compounds are extracted using chosen method.

5. Filtration: Extract is filtered to remove impurities.

6. Concentration: Extract may be concentrated through evaporation or other methods.

The resulting spinach extract can be standardized to contain specific levels of bioactive compounds like lutein and beta-carotene.

What are the different  dosage forms  of   Spinach Extract Manufactured  by  MEDIOCON INC?

Spinach extract is available in various dosage forms, including:

Oral Dosage Forms

1. Capsules: Containing powdered spinach extract or oil-based extracts.

2. Tablets: Compressed tablets containing spinach extract.

3. Powders: Loose powders for adding to food or beverages.

Skincare Dosage Forms

1. Topical creams: Moisturizing creams with spinach extract.

2. Serums: Lightweight serums with antioxidant-rich spinach extract.

Other Forms

1. Juice: Fresh spinach juice or concentrated juice extracts.

2. Softgels: Soft gelatin capsules containing spinach extract oil.

These dosage forms cater to different needs, such as dietary supplementation, skincare, or specific health benefits. Always follow recommended dosages and consult with a healthcare professional if necessary.

 How Spinach Extract Manufactured by MEDIOCON INC   Dosage Forms are prepared?

Spinach extract dosage forms are prepared through various processes, depending on the desired form:

Capsules and Tablets

1. Extraction: Spinach extract is obtained through solvent extraction, cold pressing, or other methods.

2. Standardization: Extract is standardized to contain specific levels of bioactive compounds.

3. Formulation: Extract is mixed with excipients and fillers.

4. Encapsulation or tableting: Mixture is filled into capsules or compressed into tablets.

Powders

1. Drying: Spinach extract is dried to remove excess moisture.

2. Milling: Dried extract is milled into a fine powder.

3. Blending: Powder is blended with other ingredients (if necessary).

Topical Creams and Serums

1. Extraction: Spinach extract is obtained through suitable methods.

2. Formulation: Extract is mixed with skincare ingredients, such as emollients and moisturizers.

3. Blending: Mixture is blended to achieve desired consistency and texture.

4. Filling: Product is filled into containers.

 

Quality control measures ensure the final product meets standards for purity, potency, and safety.

What are the appropriate Dosage forms of Spinach Extract Manufactured  by  MEDIOCON   INC?                

The appropriate dosage forms of Spinach Extract depend on the intended use and desired benefits. Here are some common dosage forms:

For Dietary Supplementation

1. Capsules: Containing standardized extract with antioxidants like lutein and beta-carotene.

2. Tablets: Formulated with extract and other nutrients to support overall health.

For Skincare

1. Topical creams: Moisturizing creams with antioxidant-rich spinach extract.

2. Serums: Lightweight serums with extract and other skincare ingredients.

For Eye Health

1. Capsules: Containing lutein and zeaxanthin-rich spinach extract.

Other Forms

1. Powders: For adding to food or beverages.

The choice of dosage form depends on individual needs and preferences. Always follow recommended dosages and consult with a healthcare professional if necessary.

When should Spinach Extract Manufactured by MEDIOCON INC be taken?

The timing of taking Spinach Extract depends on the intended use and individual needs. Here are some general guidelines:

For Dietary Supplementation

1. With meals: Taking with meals may enhance absorption and minimize stomach upset.

For Eye Health

1. Consistently: Take regularly, ideally with a meal, to support eye health.

For Skincare

1. Topical application: Apply topically as directed, usually morning and night.

General Recommendations

1. Follow label instructions: Adhere to recommended dosage and timing.

2. Consult a healthcare professional: If you have specific health concerns or questions.

Timing may vary depending on individual needs and product specifications.

 What are the effects And Side effects of Spinach Extract Manufactured by MEDIOCON INC?

Spinach extract has various effects and potential side effects:

Effects:

- Antioxidant Properties: Rich in antioxidants like beta-carotene and lutein, which help protect cells from damage.

- Eye Health: Supports eye health and may reduce the risk of age-related macular degeneration.

- Anti-Inflammatory Benefits: May help reduce inflammation and oxidative stress.

- Immune System Boost: Strengthens the immune system, helping the body fight off infections.

- Skin Health: Improves skin texture and protects against sun damage.

- Muscle Growth: May support muscle growth and strength.

- Weight Loss: Delays fat digestion, reduces appetite, and increases weight loss.

Side Effects:

- Diarrhea: May cause diarrhea due to high fiber and water content.

- Allergic Reactions: Can cause allergic reactions, such as itching, hives, or swelling, especially in individuals sensitive to latex or certain molds.

- Kidney Stones: May contribute to the formation of kidney stones due to high oxalate content.

- Mineral Absorption: May decrease absorption of minerals like calcium, magnesium, and zinc.

- Blood Sugar Levels: May lower blood sugar levels, potentially interacting with diabetes medications.

- Interactions with Medications: May interact with blood thinners, thyroid medications, and certain antibiotics.

Precautions:

- Pregnancy and Breastfeeding: Limited research on safety; consult a healthcare professional before using spinach extract.

- Surgery: Stop using spinach extract at least 2 weeks before scheduled surgery.

- Kidney Disease: May worsen kidney disease due to high oxalate content.

- Infants: Not recommended for infants under 4 months due to risk of methemoglobinemia

  How is Spinach Extract Manufactured by MEDIOCON  INC  Tested Qualitatively?

Spinach extract is tested qualitatively using various analytical techniques to ensure its quality, purity, and potency. Some common methods include:

Analytical Techniques

1. High-Performance Liquid Chromatography (HPLC): Separates and identifies bioactive compounds like lutein and beta-carotene.

2. Spectroscopy: Analyzes the extract's absorption spectrum.

3. Mass Spectrometry (MS): Identifies and quantifies compounds based on their mass-to-charge ratio.

Quality Control Parameters

1. Purity: Testing for contaminants, heavy metals, and adulterants.

2. Potency: Measuring the concentration of bioactive compounds.

3. Identity: Verifying the extract's botanical identity.

Testing Methods

1. Standardization: Ensuring consistent levels of bioactive compounds.

2. Fingerprinting: Creating a unique chromatographic profile for the extract.

These tests help ensure the extract meets quality standards and is safe for use in various applications.

   Which tests are performed on Spinach Extract Manufactured by  MEDIOCON INC ?

Spinach extract undergoes various tests to ensure its quality, purity, and potency. Some common tests include:

Chemical Tests

1. HPLC (High-Performance Liquid Chromatography): Measures the content of bioactive compounds like lutein and beta-carotene.

2. Spectrophotometry: Analyzes the extract's absorption spectrum.

Physical Tests

1. Appearance: Verifies the extract's color, texture, and appearance.

2. Solubility: Tests the extract's solubility in various solvents.

Purity and Contamination Tests

1. Heavy Metal Analysis: Detects the presence of heavy metals like lead, mercury, and arsenic.

2. Microbial Contamination: Tests for the presence of microorganisms like bacteria, yeast, and mold.

Standardization Tests

1. Bioactive Compound Content: Measures the content of specific bioactive compounds.

2. Potency: Verifies the extract's potency and effectiveness.

These tests help ensure the extract meets quality standards and is safe for use in various applications.

What are the challenges in Manufacturing of Spinach Extract Manufactured by MEDIOCON   INC API?

The challenges in manufacturing Spinach Extract API include¹ ² ³:

- Regulatory Compliance: Keeping up with constantly changing regulations and ensuring compliance with Good Manufacturing Practices (GMP) standards.

- High Costs: Infrastructure and equipment upgrades can be expensive, and manufacturers may need to explore government schemes and subsidies.

- Documentation Burden: Maintaining detailed records can be time-consuming, but adopting digital tools can help automate documentation and record-keeping.

- Employee Resistance: Training and implementing new practices may face resistance; fostering a culture of quality and safety is essential.

- Raw Material Quality Control: Ensuring the quality and suitability of raw materials is crucial, including testing for identity, potency, and impurities.

- Process Validation: Validating all manufacturing processes to ensure consistent product quality, including reaction, filtration, and drying.

- Environmental, Health, and Safety (EHS) Compliance: Proper training for employees, provision of personal protective equipment, and emergency response plans are necessary.

- Scaling Up Production: Unexpected outcomes, such as new impurities or increased impurity levels, can occur during scale-up, requiring close monitoring and R&D involvement.

- Quality Control and Assurance: Testing intermediate and final API batches for compliance with specifications, and regular audits to identify and address gaps.

- Supply Chain Complexities: Managing relationships with external partners, such as suppliers and contractors, is essential for smooth manufacturing operations.

To overcome these challenges, manufacturers can:

- Implement Robust Quality Management Systems: Including standard operating procedures, internal audits, and corrective and preventive actions.

- Invest in Real-Time Monitoring: Utilizing technologies like IoT sensors and advanced analytics platforms to gain insights into production processes.

- Develop Comprehensive Training Programs: Providing hands-on training and ongoing education to keep employees informed about new technologies and regulatory changes.

- Improve Communication and Collaboration: Establishing clear communication protocols and regular meetings with external partners and cross-functional teams.

What are the challenges in manufacturing of Spinach Extract Manufactured by MEDIOCON  INC ’s Dosage forms?

Manufacturing spinach extract dosage forms poses several challenges, including¹ ² ³:

- Stability Issues: Spinach extract can be susceptible to chemical and physical changes over time, leading to degradation, alteration of potency, or contamination. This is particularly true for liquid dosage forms.

- Microbial Contamination: Liquid dosage forms are prone to microbial contamination, which can lead to product recall and safety concerns. This risk can be mitigated with proper preservatives and manufacturing conditions.

- Poor Solubility: Some components of spinach extract may have poor solubility, leading to precipitation, sedimentation, or clogging of equipment during manufacturing.

- Particle Aggregation: Solid particles in liquid formulations can aggregate over time, resulting in inconsistent dosing and potential blockages in drug delivery devices.

- Container Closure Integrity: Inadequate closure systems can allow oxygen or moisture to enter, causing product degradation, contamination, or reduced shelf life.

- Uniformity and Dosing Accuracy: Ensuring uniform distribution of the active ingredients and accurate dosing can be challenging, particularly in liquid or suspension formulations.

- pH and Buffering: The pH of the formulation can impact stability and efficacy of the spinach extract, requiring careful control and buffering.

- Viscosity and Injectability: For parenteral formulations, viscosity control is crucial for easy injectability and maintaining stability.

- Storage and Stability: Spinach extract dosage forms, especially biologics, may require controlled storage environments to prevent degradation due to temperature or light exposure.

- Regulatory Compliance: Manufacturers must adhere to Good Manufacturing Practices (GMP) standards and regulatory requirements to ensure product quality and safety.

To overcome these challenges, manufacturers can implement robust quality management systems, invest in real-time monitoring, and develop comprehensive training programs for employees.

What is the Packing for Spinach Extract Manufactured by MEDIOCON INC?

Spinach extract packing varies depending on the manufacturer and product specifications. Here are some common packaging options:

- Double Layer Poly Bag: 1 Kilogram packaging size, often used for powder forms

- HDPE (High-Density Polyethylene) Drum: Available in various sizes, including 1 Kg, 5 Kg, and 25 Kg, often used for powder and liquid forms

- Packet: Used for packaging sizes like 1 Kg, 2 Kg, and 25 Kg

- Plastic Container: Used for packaging sizes like 5 Kg

- Paper Drum: Used for packaging sizes like 25 Kg, often for organic or specialty products

Some manufacturers also use sealed, reusable bottles for liquid extracts, ensuring quality and ease of storage. Packaging details may vary based on the intended use, product form, and manufacturer specifications

What is shelf life Of Spinach Extract Manufactured by MEDIOCON INC? 

The shelf life of spinach extract varies depending on the product specifications and storage conditions. Generally, spinach extract powder has a shelf life of 2 years when stored properly in a cool, dry environment. Some products may have a longer shelf life, such as 24 months, as seen in certain red spinach extract products.

 

Factors Affecting Shelf Life:

 

- Storage Conditions: Cool, dry environment

- Packaging: Airtight containers, aluminum foil bags, or drums

- Product Specifications: Concentration of active ingredients, presence of preservatives

Tips for Maintaining Shelf Life:

- Store in airtight containers to prevent moisture and air exposure

- Keep away from direct sunlight and heat sources

- Follow recommended storage conditions and handling procedures

It's essential to check the product label or consult with the manufacturer for specific shelf life information, as it may vary depending on the product formulation and storage conditions.

What should the label claim for Spinach Extract Manufactured by MEDIOCON INC   Include?

The label claim for Spinach Extract should include:

Essential Information

1. Product Name: Spinach Extract or specific product name.

2. Active Ingredients: List of bioactive compounds (e.g., lutein, beta-carotene).

3. Concentration: Percentage or amount of active ingredients.

4. Net Weight: Quantity of product.

Usage and Safety

1. Directions for Use: Recommended dosage and usage.

2. Warnings: Potential allergens, interactions, or side effects.

3. Precautions: Specific precautions for certain populations (e.g., pregnant women).

Quality and Compliance

1. Manufacturer Information: Name, address, and contact details.

2. Batch Number: Unique identifier for quality control.

3. Expiry Date: Shelf life or expiration date.

4. Certifications: Relevant certifications (e.g., GMP, organic).

Additional Claims

1. Health Benefits: Supported health benefits (e.g., eye health, antioxidant support).

2. Vegetarian/Vegan: Indication of suitability for specific diets.

Ensure label claims comply with regulatory requirements and are substantiated by scientific evidence.

Where can Spinach Extract Manufactured by MEDIOCON INC are procured?

Spinach Extract Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

FOR API

MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com           

GST No: 27DHUPM2366D1ZZ

For Dosage Forms :

- Online Marketplaces: You can find Spinach Extract Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in your area for Spinach Extract Manufactured by MEDIOCON INC products.

Remember to ensure the quality and authenticity of the Spinach Extract Manufactured by MEDIOCON INC product, regardless of the procurement source.