Watermelon Seed Extract 90244-99-8 Manufactured by MEDIOCON INC

 

 

Watermelon Seed Extract Manufactured by MEDIOCON INC     

 

   Name: Watermelon Seed Extract

   CAS No:  90244-99-8

Molecular Weight: NA

  Molecular formula:   NA

Synonyms:  citrullus lanatus seed oil, also known as Kalahari oil or Otanga oil

Appearance:  pale yellow or golden color.

   Solubility : 

 Protein Solubility: Watermelon seed protein concentrate shows high solubility in alkaline environments, with over 80% solubility at pH 10. In contrast, its solubility is lower in acidic mediums, with maximum solubility below 40%. The protein's solubility is influenced by its amino acid composition and structure.

    Use :

Watermelon seed extract has various uses due to its nutritional and potential health benefits. Some of the uses include:

1. Dietary supplement: Rich in protein, vitamins, and minerals, watermelon seed extract is used as a dietary supplement to support overall health and wellness.

2. Antioxidant properties: The extract's antioxidant properties may help protect against oxidative stress and inflammation.

3. Cardiovascular health: Watermelon seed extract may help support cardiovascular health by reducing blood pressure and improving lipid profiles.

4. Anti-inflammatory effects: The extract's anti-inflammatory properties may help alleviate symptoms of conditions like arthritis.

5. Skin and hair care: Watermelon seed extract is sometimes used in skincare and haircare products due to its potential benefits for skin and hair health.

6. Food ingredient: Watermelon seed extract can be used as a functional food ingredient, adding nutritional value and potential health benefits to various products.

7. Pharmaceutical applications: The extract's bioactive compounds may have potential therapeutic applications, such as anti-diabetic or anti-cancer effects.

These uses are based on traditional knowledge and some scientific studies, but more research is needed to confirm the efficacy and safety of watermelon seed extract for specific uses.

 How is  Watermelon Seed Extract manufactured by MEDIOCON INC Synthesized?

Watermelon seed extract is typically synthesized through various extraction methods, including:

1. Solvent extraction: Using solvents like hexane, ethanol, or water to extract bioactive compounds.

2. Cold pressing: Mechanical pressing of watermelon seeds to extract oil.

3. Enzymatic extraction: Using enzymes to break down seed components and release bioactive compounds.

4. Supercritical fluid extraction: Using supercritical fluids, like CO2, to extract bioactive compounds.

5. Aqueous extraction: Using water as a solvent to extract water-soluble compounds.

 

The choice of extraction method depends on the desired bioactive compounds, extract quality, and intended use. Some methods may be combined or followed by additional steps like filtration, purification, or concentration to obtain the final extract.

What are the different  dosage forms  of   Watermelon Seed Extract Manufactured  by  MEDIOCON INC?

Watermelon seed extract is available in various dosage forms, including:

1. Capsules: Containing powdered extract or oil.

2. Tablets: Compressed tablets with standardized extract.

3. Powder: Loose powder for mixing with food or beverages.

4. Liquid extract: Tinctures or liquid extracts for oral use.

5. Oil: Watermelon seed oil for culinary or topical use.

6. Softgels: Soft gelatin capsules containing oil or extract.

7. Tea: Dried watermelon seeds or extract in tea form.

These dosage forms offer flexibility in consumption and can be tailored to specific needs and preferences. Always follow recommended dosages and consult with a healthcare professional if necessary.

  How Watermelon Seed Extract Manufactured by MEDIOCON INC   Dosage Forms are prepared?

The preparation of watermelon seed extract dosage forms involves several steps, which may vary depending on the specific dosage form:

1. Extraction: Watermelon seeds are extracted using a suitable method (e.g., solvent extraction, cold pressing).

2. Filtration: The extract is filtered to remove impurities and improve clarity.

3. Concentration: The extract may be concentrated through evaporation or other methods.

4. Standardization: The extract is standardized to ensure consistent levels of bioactive compounds.

5. Formulation: The extract is formulated into the desired dosage form (e.g., capsules, tablets, powder).

6. Excipient selection: Suitable excipients (e.g., fillers, binders, lubricants) are selected to support the formulation.

7. Manufacturing: The dosage form is manufactured according to Good Manufacturing Practices (GMPs).

8. Quality control: The final product undergoes quality control testing to ensure purity, potency, and safety.

For specific dosage forms:

- Capsules: The extract is filled into gelatin or vegetarian capsules.

- Tablets: The extract is mixed with excipients and compressed into tablets.

- Powder: The extract is dried and powdered for use in capsules or as a loose powder.

The preparation process may vary depending on the manufacturer and specific product requirements.

What are the appropriate Dosage forms of Watermelon Seed Extract Manufactured  by  MEDIOCON   INC?                

MEDIOCON INC's Watermelon Seed Extract dosage forms are likely similar to those of other manufacturers, given the common practices in the industry. While I couldn't find specific information on MEDIOCON INC's products, here are some common dosage forms for Watermelon Seed Extract¹ ²:

- Capsules: Containing powdered extract or oil, these capsules support overall health and wellness.

- Tablets: Compressed tablets with standardized extract, providing a convenient way to consume the benefits of watermelon seeds.

- Powder: A loose powder that can be mixed with food or beverages, offering flexibility in consumption.

- Liquid Extract: Tinctures or liquid extracts for oral use, often containing a specified amount of bioactive compounds.

- Oil: Watermelon seed oil for culinary or topical use, rich in healthy fats and antioxidants.

- Softgels: Soft gelatin capsules containing oil or extract, providing a easily digestible form of the supplement.

Some extracts may be made with:

- 20-30% Ethanol Alcohol: Used as a solvent to extract bioactive compounds.

- Vegetable Glycerin: Used as an alternative to alcohol for those who prefer or require it

When should Watermelon Seed Extract Manufactured by MEDIOCON INC be taken?

The optimal time to take watermelon seed extract depends on the individual's health goals and needs. Here are some general guidelines:

1. With meals: Taking watermelon seed extract with meals may enhance absorption and reduce potential stomach upset.

2. Morning or afternoon: Some people prefer taking it in the morning or afternoon to support energy and overall well-being.

3. Before bedtime: Others may find it helpful to take it before bedtime to promote relaxation and support sleep.

It's essential to follow the recommended dosage and consult with a healthcare professional to determine the best time for your specific needs and health goals.

Additionally, consider the following:

- Consistency: Take the extract consistently, ideally at the same time every day.

- Food interactions: Be aware of potential interactions with food or other supplements.

- Health conditions: Consult with a healthcare professional if you have underlying health conditions or take medications.

Always prioritize your health and well-being by consulting with a healthcare professional for personalized guidance.

 What are the effects And Side effects of Watermelon Seed Extract Manufactured by MEDIOCON INC?

Watermelon seed extract is generally considered safe and well-tolerated. However, like any supplement, it may have some effects and potential side effects:

Potential Benefits:

1. Antioxidant properties: May help protect against oxidative stress and inflammation.

2. Cardiovascular health: May support heart health by reducing blood pressure and improving lipid profiles.

3. Anti-inflammatory effects: May help alleviate symptoms of conditions like arthritis.

4. Digestive health: May support digestive health and relieve symptoms of constipation.

Potential Side Effects:

1. Allergic reactions: Rarely, some individuals may experience allergic reactions, such as hives or itching.

2. Digestive issues: May cause stomach upset, nausea, or diarrhea in some individuals.

3. Interactions with medications: May interact with certain medications, such as blood thinners or diabetes medications.

4. Pregnancy and breastfeeding: Limited research is available on the safety of watermelon seed extract during pregnancy and breastfeeding.

Precautions:

1. Consult a healthcare professional: Before taking watermelon seed extract, especially if you have underlying health conditions or take medications.

2. Monitor blood sugar levels: If you have diabetes, monitor your blood sugar levels closely.

3. Monitor blood pressure: If you have hypertension, monitor your blood pressure regularly.

Contraindications:

1. Allergies: Avoid watermelon seed extract if you have known allergies to watermelon or related plants.

2. Surgery: Stop taking watermelon seed extract at least 2 weeks before surgery.

It's essential to consult with a healthcare professional to discuss potential benefits and risks and determine if watermelon seed extract is suitable for your individual needs.

  How is Watermelon Seed Extract Manufactured by MEDIOCON  INC  Tested Qualitatively?

Qualitative testing of watermelon seed extract involves various methods to assess its quality, purity, and composition. Some common tests include:

1. High-Performance Liquid Chromatography (HPLC): Analyzes bioactive compounds, such as flavonoids and phenolic acids.

2. Gas Chromatography-Mass Spectrometry (GC-MS): Identifies and quantifies volatile compounds.

3. Spectroscopy (UV-Vis, FTIR): Analyzes molecular structure and functional groups.

4. Proximate analysis: Determines moisture, ash, protein, and fat content.

5. Microbial testing: Assesses microbial contamination, such as bacteria, yeast, and mold.

6. Heavy metal testing: Detects presence of heavy metals, like lead, mercury, and arsenic.

7. Pesticide residue testing: Checks for presence of pesticide residues.

These tests help ensure the extract's quality, safety, and efficacy. Manufacturers may also conduct additional tests specific to their product requirements.

   Which tests are performed on Watermelon Seed Extract Manufactured by  MEDIOCON INC ?

Watermelon seed extract undergoes various tests to ensure its quality, safety, and efficacy. Some common tests include:

Physical and Chemical Tests:

1. Moisture content: Determines the extract's moisture level.

2. Ash content: Measures the extract's ash content.

3. pH: Determines the extract's acidity or alkalinity.

4. Solubility: Tests the extract's solubility in various solvents.

Analytical Tests:

1. HPLC (High-Performance Liquid Chromatography): Analyzes bioactive compounds, such as flavonoids and phenolic acids.

2. GC-MS (Gas Chromatography-Mass Spectrometry): Identifies and quantifies volatile compounds.

3. Spectroscopy (UV-Vis, FTIR): Analyzes molecular structure and functional groups.

Microbiological Tests:

1. Microbial contamination: Tests for presence of microorganisms, such as bacteria, yeast, and mold.

2. Sterility testing: Ensures the extract is free from microbial contamination.

Safety Tests:

1. Heavy metal testing: Detects presence of heavy metals, like lead, mercury, and arsenic.

2. Pesticide residue testing: Checks for presence of pesticide residues.

Quality Control Tests:

1. Identity testing: Verifies the extract's identity and authenticity.

2. Purity testing: Ensures the extract's purity and freedom from adulterants.

3. Potency testing: Determines the extract's bioactive compound content.

These tests help ensure the watermelon seed extract meets quality, safety, and efficacy standards.

What are the challenges in Manufacturing of Watermelon Seed Extract Manufactured by MEDIOCON   INC API?

The manufacturing of Watermelon Seed Extract API (Active Pharmaceutical Ingredient) faces several challenges, including:

1. Raw material sourcing: Ensuring consistent quality and supply of watermelon seeds.

2. Extraction method: Optimizing extraction methods to preserve bioactive compounds.

3. Standardization: Achieving consistent levels of bioactive compounds in the extract.

4. Purity and contamination: Ensuring the extract is free from contaminants, heavy metals, and pesticides.

5. Stability and shelf-life: Maintaining the extract's stability and shelf-life.

6. Regulatory compliance: Meeting regulatory requirements and standards.

7. Scalability: Scaling up production while maintaining quality and consistency.

8. Bioactive compound variability: Managing variability in bioactive compound levels due to factors like seed variety, growing conditions, and processing methods.

9. Quality control: Implementing robust quality control measures to ensure batch-to-batch consistency.

10. Cost-effective production: Balancing production costs with quality and efficacy requirements.

These challenges require careful consideration and optimization to ensure the production of high-quality Watermelon Seed Extract API.

What are the challenges in manufacturing of Watermelon Seed Extract Manufactured by MEDIOCON  INC ’s Dosage forms?

The manufacturing of Watermelon Seed Extract dosage forms faces several challenges, including:

1. Formulation stability: Ensuring the extract's stability and bioavailability in the dosage form.

2. Excipient compatibility: Selecting excipients that are compatible with the extract.

3. Uniformity and content: Achieving uniform distribution of the extract in the dosage form.

4. Moisture sensitivity: Managing moisture levels to prevent degradation or instability.

5. Scalability: Scaling up production while maintaining quality and consistency.

6. Regulatory compliance: Meeting regulatory requirements and standards for dosage forms.

7. Quality control: Implementing robust quality control measures to ensure batch-to-batch consistency.

8. Bioavailability and absorption: Ensuring the extract's bioavailability and absorption in the body.

9. Shelf-life and storage: Maintaining the dosage form's stability and shelf-life.

10. Cost-effective production: Balancing production costs with quality and efficacy requirements.

Additionally, specific dosage forms may have unique challenges, such as:

- Capsules: Ensuring uniform filling and minimizing capsule-to-capsule variability.

- Tablets: Achieving optimal compression and hardness.

- Liquid extracts: Ensuring stability and preventing sedimentation or separation.

These challenges require careful consideration and optimization to ensure the production of high-quality Watermelon Seed Extract dosage forms.

What is the Packing for Watermelon Seed Extract Manufactured by MEDIOCON INC?

Watermelon Seed Extract packaging typically includes:

1. Bottles: Glass or plastic bottles with tight-fitting lids.

2. Capsules or tablets containers: Bottles or blister packs for capsule or tablet forms.

3. Pouches or sachets: Flexible packaging for powdered or granular extracts.

4. Drums or containers: Larger containers for bulk packaging.

Packaging materials may include:

1. Labeling: Labels with product information, instructions, and warnings.

2. Desiccants: Desiccant packets to maintain dryness.

3. Tamper-evident packaging: Packaging designed to prevent tampering.

The packaging is designed to:

1. Protect the product: From light, moisture, and contamination.

2. Ensure stability: Maintain the extract's potency and shelf-life.

3. Provide convenience: Easy to use and store.

The specific packaging may vary depending on the product form, intended use, and regulatory requirements.

What is shelf life Of Watermelon Seed Extract Manufactured by MEDIOCON INC? 

The shelf life of Watermelon Seed Extract can vary depending on several factors, including:

1. Storage conditions: Temperature, humidity, and light exposure.

2. Packaging: Type of container, closure, and protection from moisture and light.

3. Formulation: Type of extract, presence of preservatives, and other ingredients.

Typically, the shelf life of Watermelon Seed Extract can range from:

1. 2-3 years: For dried extracts stored in airtight containers.

2. 1-2 years: For liquid extracts or tinctures stored in glass bottles.

It's essential to check the product label or consult with the manufacturer for specific shelf life information and storage recommendations to ensure the product's potency and safety.

What should the label claim for Watermelon Seed Extract Manufactured by MEDIOCON INC   Include?

The label claim for Watermelon Seed Extract should include:

1. Product name: Watermelon Seed Extract or Citrullus lanatus Seed Extract.

2. Active ingredients: List of bioactive compounds, such as citrulline, arginine.

3. Amount per serving: Quantity of extract per serving (e.g., capsule, tablet, or liquid dose).

4. Serving size: Recommended dosage and frequency.

5. Purpose: Intended use, such as cardiovascular health or antioxidant support.

6. Warning: Any relevant warnings, such as pregnancy, breastfeeding, or interactions with medications.

7. Storage: Storage instructions to maintain potency and shelf-life.

8. Expiration date: Date after which the product should not be used.

9. Manufacturer information: Name and contact details of the manufacturer or distributor.

10. Regulatory compliance: Compliance with relevant regulatory standards.

The label should be clear, accurate, and compliant with regulatory requirements.

Where can Watermelon Seed Extract Manufactured by MEDIOCON INC are procured?

Watermelon Seed Extract Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

FOR API

MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com           

GST No: 27DHUPM2366D1ZZ

For Dosage Forms :

- Online Marketplaces: You can find Watermelon Seed Extract Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in your area for Watermelon Seed Extract Manufactured by MEDIOCON INC products.

Remember to ensure the quality and authenticity of the Watermelon Seed Extract Manufactured by MEDIOCON INC product, regardless of the procurement source.