Echinacea Purpurea Extract 90028-20-9 Manufactured by MEDIOCON INC

 

 

Echinacea Purpurea Extract Manufactured by MEDIOCON INC     

 

   Name: Echinacea Purpurea Extract

   CAS No:  90028-20-9

Molecular Weight:  NA

Molecular formula:   NA

Synonyms:  purple coneflower extract, eastern purple coneflower extract, and other less common names such as coneflower extract and Red Sunflower extract.

Appearance:  brownish-yellow to brown-green fine powder.

 Solubility :  water-soluble

Use :

Echinacea purpurea extract is commonly used for:

Immune System Support1. Boosting immunity: Enhances the body's natural defense against infections.

2. Cold and flu prevention: May help reduce the severity and duration of cold and flu symptoms.

Anti-Inflammatory Effects1. Reducing inflammation: May help alleviate inflammation and related conditions.

Antiviral and Antibacterial Properties1. Fighting infections: Exhibits antimicrobial properties, potentially helping to combat infections.

Other Uses1. Skin health: May support skin health and wound healing.

2. Respiratory health: May help alleviate respiratory issues, such as bronchitis and coughs.

Forms1. Capsules: Available in various strengths and formulations.

2. Tablets: Often combined with other herbs or vitamins.

3. Liquid extracts: May be used sublingually or added to beverages.

Precautions1. Allergies: Individuals with allergies to plants in the Asteraceae family may experience allergic reactions.

2. Interactions: May interact with certain medications, such as immunosuppressants.

3. Pregnancy and breastfeeding: Consult a healthcare professional before using Echinacea purpurea extract.

As with any supplement, consult a healthcare professional before using Echinacea purpurea extract, especially if you have underlying medical conditions or take medications.

 How is  Echinacea Purpurea Extract manufactured by MEDIOCON INC Synthesized?

Echinacea purpurea extract is typically synthesized through various extraction methods, including:

Extraction Methods1. Solvent extraction: Uses solvents like ethanol, methanol, or water to extract bioactive compounds.

2. Hydroethanolic extraction: Combines water and ethanol to extract a broad range of compounds.

3. Aqueous extraction: Uses water as the solvent to extract water-soluble compounds.

4. Supercritical fluid extraction: Utilizes supercritical fluids, like CO2, to extract compounds without solvents.

Processing Steps1. Harvesting: Echinacea purpurea plants are harvested, typically during peak flowering.

2. Drying: Plants are dried to remove excess moisture.

3. Grinding: Dried plants are ground into a fine powder.

4. Extraction: The powder is subjected to the chosen extraction method.

5. Filtration: The extract is filtered to remove impurities.

6. Concentration: The extract may be concentrated through evaporation or other methods.

7. Standardization: The extract is standardized to specific levels of bioactive compounds, such as alkamides and phenolic acids.

Quality Control1. Testing: The extract is tested for purity, potency, and contaminants.

2. Certification: Some products may be certified by third-party organizations, ensuring quality and authenticity.

The choice of extraction method and processing steps can impact the quality and efficacy of the final product.

What are the different  dosage forms  of   Echinacea Purpurea Extract Manufactured  by  MEDIOCON INC?

Echinacea purpurea extract is available in various dosage forms, including:

Dosage Forms1. Capsules: Containing dried extract or oil-based extracts.

2. Tablets: Often combined with other herbs or vitamins.

3. Liquid extracts: May be used sublingually or added to beverages.

4. Tinctures: Concentrated liquid extracts.

5. Teas: Dried roots or flowers steeped in hot water.

6. Topical preparations: Creams, ointments, or gels for skin application.

7. Powders: Can be used to make teas, capsules, or added to food.

Formulations1. Single-herb formulations: Containing only Echinacea purpurea extract.

2. Combination products: Blended with other herbs, vitamins, or minerals.

Strengths and Concentrations1. Standardized extracts: Containing specific levels of bioactive compounds (e.g., alkamides, phenolic acids).

2. Variable strengths: Different products may have varying concentrations of Echinacea purpurea extract.

When choosing a product, consider factors like dosage, formulation, and quality to ensure efficacy and safety. Consult a healthcare professional for personalized guidance.

 How Echinacea Purpurea Extract Manufactured by MEDIOCON INC   Dosage Forms are prepared?

Echinacea purpurea extract dosage forms are prepared through various methods depending on the desired form. Here's an overview of the preparation process for different forms:

 

Preparation Methods- Tincture: Made by soaking dried Echinacea root or aerial parts in high-proof alcohol (at least 40%) for 4-6 weeks, shaking gently every few days. Strain and store in a cool, dark place.

- Tea: Prepare by steeping 1-2 teaspoons of dried Echinacea herb (leaves, flowers, or roots) in boiling water for 10-15 minutes. Strain and drink.

- Capsules/Tablets: Commercially prepared from dried and powdered Echinacea plant material, often standardized to specific levels of active compounds.

- Liquid Extracts: Similar to tinctures but may be more concentrated, produced using specialized equipment like Soxhlet extractors.

- Topical Preparations: Creams, ointments, or gels are made by incorporating Echinacea extract into a topical base, often for skin issues or wound healing.

 

Quality Control- Standardization: Many products are standardized to specific levels of active compounds like alkamides, caffeic acid derivatives, or phenolic acids.

- Quality Assurance: Reputable manufacturers follow good manufacturing practices (GMPs) to ensure product purity and potency.

What are the appropriate Dosage forms of Echinacea Purpurea Extract Manufactured  by  MEDIOCON   INC?                

The appropriate dosage forms of Echinacea purpurea extract depend on the intended use and individual needs. Here are some common dosage forms and their uses:

Dosage Forms1. Capsules: Suitable for immune system support, cold and flu prevention, and general health.

2. Tablets: Often used for immune system support and cold prevention, may be combined with other herbs or vitamins.

3. Liquid extracts: May be used sublingually or added to beverages, suitable for immune system support and cold prevention.

4. Tinctures: Concentrated liquid extracts, often used sublingually or added to beverages, suitable for immune system support.

5. Teas: Suitable for general health, immune system support, and relaxation.

6. Topical preparations: Creams, ointments, or gels for skin application, suitable for wound healing and skin issues.

Dosage Considerations1. Standardization: Look for products standardized to specific levels of bioactive compounds (e.g., alkamides, phenolic acids).

2. Dosage: Follow recommended dosages, typically 300-500 mg per day for capsules or tablets.

3. Duration: Consult a healthcare professional for long-term use or high doses.

Individual Needs1. Age: Consult a healthcare professional for children or elderly individuals.

2. Health status: Consult a healthcare professional for individuals with underlying medical conditions or taking medications.

3. Pregnancy and breastfeeding: Consult a healthcare professional before using Echinacea purpurea extract.

 

When choosing a dosage form, consider individual needs, intended use, and product quality to ensure efficacy and safety. Consult a healthcare professional for personalized guidance.

When should Echinacea Purpurea Extract Manufactured by MEDIOCON INC be taken?

Echinacea purpurea extract can be taken:

Timing1. At the onset of cold or flu symptoms: To potentially reduce severity and duration.

2. During cold and flu season: As a preventative measure to support immune system function.

3. Regularly for immune system support: To potentially enhance overall immune function.

Considerations1. Consistency: Take consistently for optimal benefits.

2. Dosage: Follow recommended dosages.

3. Individual needs: Consult a healthcare professional for personalized guidance.

Precautions1. Pregnancy and breastfeeding: Consult a healthcare professional before using Echinacea purpurea extract.

2. Underlying medical conditions: Consult a healthcare professional if you have underlying medical conditions or take medications.

When taken appropriately, Echinacea purpurea extract may support immune system function and overall health.

 What are the effects And Side effects of Echinacea Purpurea Extract Manufactured by MEDIOCON INC?

Echinacea purpurea extract has various effects and potential side effects:

Effects1. Immune system support: May enhance immune function and reduce severity of cold and flu symptoms.

2. Anti-inflammatory properties: May help reduce inflammation and alleviate related conditions.

3. Antiviral and antibacterial properties: May help combat infections.

Side Effects1. Allergic reactions: Rarely, some individuals may experience allergic reactions, such as skin rashes or itching.

2. Gastrointestinal issues: May cause stomach upset, nausea, or diarrhea in some individuals.

3. Interactions with medications: May interact with immunosuppressants, diabetes medications, or other medications.

Precautions1. Pregnancy and breastfeeding: Consult a healthcare professional before using Echinacea purpurea extract.

2. Autoimmune disorders: Consult a healthcare professional before using Echinacea purpurea extract if you have an autoimmune disorder.

3. Long-term use: Consult a healthcare professional for long-term use or high doses.

When used appropriately, Echinacea purpurea extract is generally considered safe. However, individual results may vary, and potential interactions or side effects should be considered. Consult a healthcare professional for personalized guidance.

  How is Echinacea Purpurea Extract Manufactured by MEDIOCON  INC  Tested Qualitatively?

Echinacea purpurea extract is qualitatively tested using various methods to ensure its quality, purity, and potency. Some common testing methods include:

Chemical Testing1. High-Performance Liquid Chromatography (HPLC): Analyzes the presence and concentration of bioactive compounds like alkamides and phenolic acids.

2. Gas Chromatography (GC): Identifies and quantifies volatile compounds.

Physical Testing1. Appearance: Visual inspection for color, texture, and consistency.

2. Solubility: Tests for solubility in various solvents.

Microbiological Testing1. Microbial contamination: Tests for presence of microorganisms like bacteria, yeast, and mold.

Authentication1. DNA testing: Verifies the botanical identity of Echinacea purpurea.

Standardization1. Standardization to bioactive compounds: Ensures consistent levels of alkamides, phenolic acids, or other bioactive compounds.

Quality Control1. Good Manufacturing Practices (GMPs): Ensures manufacturing processes meet quality standards.

These testing methods help ensure the quality and efficacy of Echinacea purpurea extract products.

   Which tests are performed on Echinacea Purpurea Extract Manufactured by  MEDIOCON INC ?

Echinacea purpurea extract undergoes various tests to ensure its quality, purity, and potency. These tests include¹ ²:

- Chemical Tests

    - High-Performance Liquid Chromatography (HPLC): Analyzes the presence and concentration of bioactive compounds like alkamides and phenolic acids.

    - Content of Alkamides: Measures the percentage of alkamides calculated as dodecatetraenoic acid isobutylamides.

    - Content of Total Phenols: Measures the percentage of total phenols, including caftaric acid, chicoric acid, chlorogenic acid, and echinacoside.

- Physical Tests

    - Appearance: Visual inspection for color, texture, and consistency.

    - Loss on Drying: Measures the moisture content of the extract.

- Microbiological Tests

    - Pesticide Residues: Tests for the presence of pesticide residues.

    - Heavy Metals: Tests for the presence of heavy metals.

- Identification Tests

    - Thin-Layer Chromatographic Identification Test: Verifies the presence of chicoric acid and absence of echinacoside.

    - Presence of Isobutylalkenylamides: Tests for the presence of specific compounds.

- Other Tests

    - Acid-Insoluble Ash: Measures the acid-insoluble ash content.

    - Total Ash: Measures the total ash content.

These tests help ensure the quality and efficacy of Echinacea purpurea extract products.

What are the challenges in Manufacturing of Echinacea Purpurea Extract Manufactured by MEDIOCON   INC API?

Manufacturing Echinacea purpurea extract API poses several challenges, including¹:

- Raw Material Variability: Ensuring consistency in the quality and bioactive profile of Echinacea raw materials can be difficult due to factors like seasonal changes, cultivation practices, and geographic origin. To mitigate this, manufacturers establish partnerships with certified organic farmers and implement strict quality control measures.

- Scalability of Production: Scaling up production while maintaining product consistency is a significant challenge. Investing in scalable manufacturing processes and equipment helps address this issue.

- Regulatory Compliance: Navigating complex regulatory landscapes across different markets requires constant vigilance. A dedicated regulatory affairs team ensures compliance with international standards and regulations.

- Extraction Efficiency: Achieving optimal extraction efficiency, especially when avoiding certain solvents, requires precise control over extraction parameters. Advanced extraction technologies and continuous monitoring help maximize yield and potency.

- Quality Control and Standardization: Maintaining stringent quality control during scale-up processes is crucial. A robust quality management system, including detailed documentation and regular audits, ensures quality consistency.

- Stability and Shelf Life: Stability testing assesses how the quality of Echinacea extract changes over time, determining its shelf life and storage conditions.

- Purity and Safety Testing: Testing for heavy metals, pesticides, solvents, and microbial contamination ensures the extract's safety for consumption.

- Standardization: Standardizing the extract to contain specific levels of bioactive compounds ensures consistent efficacy across products.

Additionally, other potential challenges include²:

- Competition from Synthetic Alternatives: Increasing competition from synthetic alternatives and pharmaceuticals offering similar benefits may impact market growth.

To overcome these challenges, manufacturers like HimPharm invest in advanced extraction technologies, scalable manufacturing processes, and robust quality management systems, ensuring the production of high-quality Echinacea purpurea extract API.

What are the challenges in manufacturing of Echinacea Purpurea Extract Manufactured by MEDIOCON  INC ’s Dosage forms?

Manufacturing Echinacea purpurea extract dosage forms poses several challenges, including¹:

- Raw Material Variability: Ensuring consistency in the quality and bioactive profile of Echinacea raw materials can be difficult due to factors like seasonal changes, cultivation practices, and geographic origin. To mitigate this, manufacturers establish partnerships with certified organic farmers and implement stringent quality control measures.

- Scalability of Production: Scaling up production while maintaining product consistency is a significant challenge. Investing in scalable manufacturing processes and equipment helps address this issue.

- Regulatory Compliance: Navigating complex regulatory landscapes across different markets requires constant vigilance. A dedicated regulatory affairs team ensures compliance with international standards and regulations.

- Extraction Efficiency: Achieving optimal extraction efficiency, especially when avoiding certain solvents, requires precise control over extraction parameters. Advanced extraction technologies and continuous monitoring help maximize yield and potency.

- Quality Control and Standardization: Maintaining stringent quality control during scale-up processes is crucial. A robust quality management system, including detailed documentation and regular audits, ensures quality consistency.

- Stability and Shelf Life: Stability testing assesses how the quality of Echinacea extract changes over time, determining its shelf life and storage conditions.

- Purity and Safety Testing: Testing for heavy metals, pesticides, solvents, and microbial contamination ensures the extract's safety for consumption.

- Standardization: Standardizing the extract to contain specific levels of bioactive compounds ensures consistent efficacy across products.

Additionally, other potential challenges include:

- Interactions with Medications: Echinacea may interact with certain medications, affecting their efficacy or leading to adverse effects. Consulting healthcare professionals before combining Echinacea with other medications is crucial.

- Allergic Reactions: Rarely, some individuals may experience allergic reactions, particularly those allergic to plants in the daisy family. Discontinuing use and seeking medical attention if symptoms occur is essential.

To overcome these challenges, manufacturers invest in advanced extraction technologies, scalable manufacturing processes, and robust quality management systems, ensuring the production of high-quality Echinacea purpurea extract dosage forms.

What is the Packing for Echinacea Purpurea Extract Manufactured by MEDIOCON INC?

Echinacea purpurea extract packing typically comes in various forms and sizes depending on the manufacturer and intended use. Some common packaging options include:

- Drums: 25kg/drum, often used for bulk quantities

- Paper drums with plastic bags: Containing 20-25kg of product, suitable for large-scale applications

- HDPE drums: Available in sizes ranging from 1kg to 25kg

 

The packaging materials used are often designed to protect the product from moisture, light, and other environmental factors that may affect its quality. It's common to see¹ ² ³:

- Double-layer plastic bags or food-grade PE bags inside the drums for added protection

- Airtight containers to maintain product freshness and potency

Manufacturers may also provide customized packaging options depending on specific requirements. If you're looking for more information on a particular product or packaging option, it's best to contact the manufacturer directly.

What is shelf life Of Echinacea Purpurea Extract Manufactured by MEDIOCON INC? 

The shelf life of Echinacea purpurea extract typically ranges from 1 to 2 years, depending on storage conditions and product formulation.

Factors Affecting Shelf Life:

- Storage Conditions: Cool, dry places away from direct sunlight and moisture help preserve the extract's potency.

- Product Formulation: The type of extract, concentration, and presence of other ingredients can impact shelf life.

General Guidelines:

- Typical Shelf Life: 2 years when stored properly in cool, dry conditions.

- Optimal Usage: Use within 1 year for freshest quality.

Storage Tips:

- Store in airtight containers to maintain freshness and potency.

- Keep away from strong light and moisture.

- Follow manufacturer instructions for specific storage recommendations

What should the label claim for Echinacea Purpurea Extract Manufactured by MEDIOCON INC   Include?

The label claim for Echinacea purpurea extract should include:

Essential Information1. Product Name: Clearly state the product name, including the Latin name "Echinacea purpurea".

2. Active Ingredients: Specify the amount of bioactive compounds (e.g., alkamides, phenolic acids) per serving.

3. Dosage Instructions: Provide clear dosage instructions, including recommended daily intake.

4. Warning Statements: Include warnings for potential allergic reactions or interactions with medications.

5. Storage Instructions: Provide storage instructions to maintain product potency and safety.

Additional Information1. Standardization: Specify the standardization method and level of bioactive compounds.

2. Other Ingredients: List any other ingredients, such as fillers or excipients.

3. Manufacturer Information: Include the manufacturer's name, address, and contact information.

Regulatory Compliance1. Regulatory Statements: Comply with relevant regulatory requirements (e.g., FDA, EU).

2. Label Claims: Ensure label claims are accurate and substantiated by scientific evidence.

By including this information, the label claim for Echinacea purpurea extract can provide consumers with essential information for safe and effective use.

Where can Echinacea Purpurea Extract Manufactured by MEDIOCON INC are procured?

Echinacea Purpurea Extract Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

FOR API

MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com           

GST No: 27DHUPM2366D1ZZ

For Dosage Forms :

- Online Marketplaces: You can find Echinacea Purpurea Extract Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in your area for Echinacea Purpurea Extract Manufactured by MEDIOCON INC products.

Remember to ensure the quality and authenticity of the Echinacea Purpurea Extract Manufactured by MEDIOCON INC product, regardless of the procurement source.