Saffron Extract 84604-17-1 Manufacturer Exporter MEDIOCON INC

 

 

Saffron Extract  Manufactured by MEDIOCON INC     

 

   Name: Saffron Extract

   CAS No: 84604-17-1

Molecular Weight:  NA

Molecular formula:   NA

Synonyms:  Crocus Sativus Flower Extract or Indian Saffron.

Appearance:  pale yellow to yellow-orange liquid or a red-brown powder.

 Solubility :   water-soluble.

Use :

Saffron extract, derived from the Crocus sativus flower, has various potential uses:

Health Benefits

1. Mood enhancement: Saffron extract may help alleviate symptoms of depression and anxiety.

2. Cognitive function: Some studies suggest saffron may improve memory and cognitive function.

3. Antioxidant properties: Saffron's antioxidant properties may help protect against cell damage.

Traditional Uses

1. Digestive issues: Saffron has been traditionally used to alleviate digestive problems.

2. Menstrual relief: Some women use saffron to relieve menstrual cramps and symptoms.

Other Potential Uses

1. Skin and hair care: Saffron may be used in skincare products for its antioxidant and anti-inflammatory properties.

2. Food and beverage: Saffron is a popular spice in various cuisines, adding flavor and color to dishes.

When using saffron extract, consider factors like:

- Quality and sourcing: Ensure high-quality saffron from reputable sources.

- Dosage and interactions: Consult a healthcare professional for guidance on dosage and potential interactions.

Saffron extract's potential benefits and uses make it a valuable ingredient in various applications.

 How is  Saffron Extract  manufactured by MEDIOCON INC Synthesized?

Saffron extract is typically obtained through various extraction methods, rather than synthesis. Some common methods include:

Extraction Methods

1. Solvent extraction: Using solvents like ethanol or water to extract bioactive compounds.

2. Cold pressing: Mechanical extraction of saffron's bioactive compounds.

3. Supercritical fluid extraction: Using supercritical fluids, like CO2, to extract compounds.

Processing Steps

1. Drying: Saffron stigmas are dried to preserve bioactive compounds.

2. Grinding: Dried saffron is ground into a powder.

3. Extraction: Bioactive compounds are extracted using chosen methods.

Quality Control

1. Standardization: Ensuring consistent levels of bioactive compounds, like crocin and safranal.

2. Purity testing: Detecting contaminants and adulterants.

The extraction method and processing steps can impact the quality and potency of the final saffron extract product.

What are the different  dosage forms  of   Saffron Extract  Manufactured  by  MEDIOCON INC?

Saffron extract is available in various dosage forms, including:

Oral Dosage Forms

1. Capsules: Convenient for standardized dosing.

2. Tablets: Often used for dietary supplements.

3. Liquid extracts: May be used for faster absorption.

Other Forms

1. Powder: Can be used in food, beverages, or supplements.

2. Tea: Saffron stigmas can be steeped in hot water.

Considerations

1. Standardization: Ensure consistent levels of bioactive compounds.

2. Dosage: Follow recommended dosages to avoid adverse effects.

The choice of dosage form depends on individual needs and preferences. Consult a healthcare professional for guidance on using saffron extract.

 How Saffron Extract  Manufactured by MEDIOCON INC   Dosage Forms are prepared?

Saffron extract dosage forms are prepared through various processes:

Preparation Steps

1. Raw material sourcing: High-quality saffron stigmas are sourced.

2. Extraction: Bioactive compounds are extracted using methods like solvent extraction or supercritical fluid extraction.

3. Concentration: The extract is concentrated to desired potency.

4. Formulation: The extract is formulated into desired dosage forms (e.g., capsules, tablets, liquid extracts).

Manufacturing Process

1. Standardization: The extract is standardized to ensure consistent levels of bioactive compounds.

2. Quality control: The final product is tested for purity, potency, and contaminants.

3. Packaging: The product is packaged in suitable containers to maintain stability and potency.

 

The preparation process may vary depending on the manufacturer and specific product requirements. Good manufacturing practices (GMP) are essential to ensure product quality and safety.

What are the appropriate Dosage forms of Saffron Extract  Manufactured  by  MEDIOCON   INC?                

Appropriate dosage forms of Saffron Extract include:

Dosage Forms

1. Capsules: 15-30 mg of saffron extract per capsule, standardized to 1-2% crocins.

2. Tablets: 15-60 mg of saffron extract per tablet, standardized to specific bioactive compounds.

3. Liquid extracts: 20-50 mg of saffron extract per dose, often standardized to specific bioactive compounds.

Considerations

1. Standardization: Ensure consistent levels of bioactive compounds like crocin and safranal.

2. Dosage: Follow recommended dosages (typically 30 mg/day) and consult a healthcare professional.

Product Selection

1. Look for third-party certifications (e.g., NSF International, (link unavailable)).

2. Choose products from reputable manufacturers.

3. Check the label for standardization and dosage information.

The appropriate dosage form and amount may vary depending on individual needs and health status. Consult a healthcare professional for personalized guidance.

When should Saffron Extract  Manufactured by MEDIOCON INC be taken?

The optimal timing for taking Saffron Extract depends on the individual's needs and health goals. Here are some general guidelines:

Timing Considerations

1. Morning: Taking saffron extract in the morning may help boost mood and energy levels throughout the day.

2. Before bed: Some people find that taking saffron extract before bed helps promote relaxation and improves sleep quality.

Dosage and Individual Needs

1. Consult a healthcare professional: To determine the best dosage and timing for your specific needs.

2. Start with a low dose: Gradually increase the dose as needed and under medical supervision.

Precautions

1. Pregnancy and breastfeeding: Consult a healthcare professional before using saffron extract.

2. Interactions with medications: Saffron extract may interact with certain medications, such as blood thinners.

 

It's essential to follow the recommended dosage and consult with a healthcare professional to ensure safe and effective use.

 What are the effects And Side effects of Saffron Extract  Manufactured by MEDIOCON INC?

Saffron extract has various effects and potential side effects:

Potential Benefits

1. Mood enhancement: Saffron extract may help alleviate symptoms of depression and anxiety.

2. Cognitive function: Some studies suggest saffron may improve memory and cognitive function.

3. Antioxidant properties: Saffron's antioxidant properties may help protect against cell damage.

Potential Side Effects

1. Allergic reactions: Some individuals may experience allergic reactions, such as skin irritation or respiratory issues.

2. Digestive issues: Saffron extract may cause nausea, vomiting, or stomach discomfort in some individuals.

3. Interactions with medications: Saffron extract may interact with certain medications, such as blood thinners.

Precautions

1. Pregnancy and breastfeeding: Consult a healthcare professional before using saffron extract.

2. High doses: High doses of saffron extract may cause adverse effects, such as dizziness or headache.

It's essential to consult with a healthcare professional before using saffron extract, especially if you have underlying medical conditions or take medications.

  How is Saffron Extract  Manufactured by MEDIOCON  INC  Tested Qualitatively?

Saffron extract is tested qualitatively using various methods to ensure its quality, purity, and potency. Some common tests include:

Chemical Tests

1. High-Performance Liquid Chromatography (HPLC): Analyzes bioactive compounds like crocin and safranal.

2. Spectroscopy: Measures the extract's chemical composition.

Physical Tests

1. Moisture content: Determines the extract's moisture level.

2. Colorimetric analysis: Evaluates the extract's color intensity.

Microbiological Tests

1. Microbial contamination: Detects presence of microorganisms like bacteria, yeast, or mold.

Other Tests

1. Heavy metal analysis: Detects presence of heavy metals like lead, mercury, or arsenic.

2. Pesticide residue analysis: Detects presence of pesticide residues.

These tests help ensure the saffron extract meets quality standards and is safe for consumption.

   Which tests are performed on Saffron Extract  Manufactured by  MEDIOCON INC ?

Saffron extract undergoes various tests to ensure quality, purity, and potency. Some common tests include:

Chemical Tests

1. Crocin content: Measures the level of crocin, a key bioactive compound.

2. Safranal content: Determines the level of safranal, responsible for saffron's aroma.

3. Picrocrocin content: Measures the level of picrocrocin, another bioactive compound.

Physical Tests

1. Color intensity: Evaluates the extract's color strength.

2. Moisture content: Determines the extract's moisture level.

Contaminant Tests

1. Heavy metal analysis: Detects presence of heavy metals like lead, mercury, or arsenic.

2. Pesticide residue analysis: Detects presence of pesticide residues.

3. Microbial contamination: Detects presence of microorganisms like bacteria, yeast, or mold.

Other Tests

1. Standardization: Verifies the extract's consistency and potency.

2. Authentication: Confirms the extract's authenticity and absence of adulterants.

 

These tests help ensure the saffron extract meets quality standards and is safe for consumption.

What are the challenges in Manufacturing of Saffron Extract  Manufactured by MEDIOCON   INC API?

Manufacturing Saffron Extract API poses several challenges, including¹:

- High Raw Material Costs: Saffron is one of the most expensive spices globally, making raw material costs a significant challenge.

- Complex Extraction Process: The extraction process requires specialized equipment and expertise, particularly for methods like supercritical fluid extraction.

- Regulatory Compliance: API manufacturers must comply with stringent regulations, such as Good Manufacturing Practices (GMP), to ensure product quality and safety.² ³

- Quality Control: Ensuring consistency in quality and potency of the extract is crucial, requiring robust quality control measures.

- Documentation and Record-Keeping: Maintaining detailed records of manufacturing processes, testing, and quality control is essential for regulatory compliance and product traceability.

- Environmental, Health, and Safety Compliance: API manufacturing involves handling hazardous chemicals, necessitating proper safety protocols and emergency response plans.

- Process Validation: Validating manufacturing processes to ensure consistent product quality is vital.

- Infrastructure and Equipment Upgrades: Meeting environmental and safety requirements may require significant investments in infrastructure and equipment.

- Employee Training: Providing regular training on GMP practices, safety protocols, and equipment handling is essential for maintaining high standards of production and compliance.⁴

These challenges highlight the need for careful planning, investment in infrastructure and training, and adherence to regulatory requirements to ensure the quality and safety of Saffron Extract API.

What are the challenges in manufacturing of Saffron Extract  Manufactured by MEDIOCON  INC ’s Dosage forms?

Manufacturing Saffron Extract dosage forms poses several challenges, including:

Formulation Challenges

1. Standardization and Quality Control: Ensuring consistency in the quality and potency of herbal formulations is challenging due to natural variations in plant constituents.

2. Bioavailability and Stability: Optimizing formulations for bioavailability and stability can be difficult, especially when combining multiple herbal ingredients.

Manufacturing Challenges

1. Raw Material Sourcing: Ensuring a sustainable and reliable supply of high-quality saffron is crucial.

2. Process Monitoring and Control: Implementing a comprehensive process monitoring system is essential to track critical parameters and ensure product quality.

Regulatory Challenges

1. Regulatory Compliance: Navigating complex and evolving regulatory frameworks for herbal products can be challenging, especially across different countries.

2. Documentation and Labeling: Meeting documentation requirements, safety standards, and labeling regulations is essential.

Other Challenges

1. Scientific Validation: Conducting rigorous scientific validation of efficacy and safety can be difficult, especially for traditional herbal formulations.

2. Technological Integration: Adopting advanced technologies like nanotechnology for drug delivery or innovative extraction methods may face resistance or slow adoption.

Addressing these challenges is crucial to ensure the quality, safety, and efficacy of Saffron Extract dosage forms.

What is the Packing for Saffron Extract  Manufactured by MEDIOCON INC?

Saffron extract packing varies depending on the product and intended use. Here are some common packaging options:

- Face Creams: 50gm packs, often combined with other ingredients like sandalwood or turmeric, for natural glowing skin.

- Face Packs: 35gms/1.24 oz packs, sometimes combined with retinol (Vitamin A) for skin whitening and anti-aging benefits.

- Gummies: 2-pack servings, each containing 88.5mg of saffron extract, standardized to 0.3% Safranal for consistent quality.

- Moisturizers: 30ml travel packs, providing luminous hydration with saffron extract.

- Soaps: 100gm handmade soaps, often enriched with sandalwood and saffron for natural glow and radiance.

- Liquid Extracts: Available in various packaging sizes, sometimes combined with other ingredients like green tea, cardamom, or rose petals.

- Tan Removal Packs: Enriched with saffron extract, tea tree oil, turmeric, and Multani Mitti for diminishing layered tanning and pigmentation.

- Milk Mud Masks: 50ml packs, often containing oat milk, saffron extract, and kaolin clay for brightening and tan removal.

What is shelf life Of Saffron Extract  Manufactured by MEDIOCON INC? 

Saffron extract's shelf life varies depending on storage conditions. Generally, it can last¹:

- 1-2 years at room temperature

- 2-3 years when refrigerated

- 3-4 years when frozen

 

To maximize shelf life, store saffron extract in² ³ ⁴:

- Airtight containers to prevent moisture and air exposure

- Cool, dark places away from direct sunlight and heat sources

- Low humidity environments to prevent degradation

Proper storage helps preserve saffron extract's potency, flavor, and aroma. Signs of expired saffron extract include:

- Faded color

- Weak aroma

- Lackluster flavor

Using expired saffron extract may not pose health risks, but it can result in reduced flavor and aroma. Consider replacing it to ensure optimal quality and flavor in your dishes.

What should the label claim for Saffron Extract  Manufactured by MEDIOCON INC Include?

The label claim for Saffron Extract should include:

Essential Information

1. Product name: Saffron Extract or Crocus sativus extract.

2. Active ingredients: Specify the bioactive compounds, such as crocin and safranal.

3. Concentration: Indicate the extract concentration (e.g., 1% crocins).

4. Dosage instructions: Provide recommended dosage and usage guidelines.

Regulatory Information

1. Regulatory compliance: Comply with relevant regulatory requirements (e.g., FDA, EU, or other regional regulations).

2. Label claims: Ensure label claims are substantiated by scientific evidence.

Additional Information

1. Storage instructions: Provide storage guidelines to maintain product potency and shelf life.

2. Expiration date: Include the expiration date or shelf life.

3. Manufacturer information: Include the manufacturer's name, address, and contact information.

Optional Claims

1. Standardization: Indicate standardization to specific bioactive compounds.

2. Traditional use: Mention traditional uses, such as mood enhancement or cognitive support.

Ensure label claims are accurate, compliant with regulations, and substantiated by scientific evidence.

Where can Saffron Extract  Manufactured by MEDIOCON INC are procured?

Saffron Extract  Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

FOR API

MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com           

GST No: 27DHUPM2366D1ZZ

For Dosage Forms :

- Online Marketplaces: You can find Saffron Extract Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in your area for Saffron Extract Manufactured by MEDIOCON INC products.

Remember to ensure the quality and authenticity of the Saffron Extract Manufactured by MEDIOCON INC product, regardless of the procurement source.